(59 nodes) GDP binding network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RRAS2	Ras-related protein R-Ras2 isoform a. (204 aa)
	RAB9B	Uncharacterized protein. (217 aa)
	RALA	Ras-related protein Ral-A. (206 aa)
	RAB7A	RAB7A, member RAS oncogene family. (220 aa)
	RHEB	Uncharacterized protein. (249 aa)
	ARL3	Uncharacterized protein. (350 aa)
	ENSMMUP00000064834	Uncharacterized protein. (201 aa)
	RAB31	Ras-related protein Rab-31. (194 aa)
	RAB27B	RAB27B, member RAS oncogene family. (218 aa)
	RAB5A	Uncharacterized protein. (227 aa)
	RAB35	Uncharacterized protein. (266 aa)
	GEM	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
	RAB5B	Ras-related protein Rab-5B isoform 1. (215 aa)
	RAB22A	RAB22A, member RAS oncogene family. (198 aa)
	DYNC1LI1	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
	RAP1B	Ras-related protein Rap-1b isoform 1. (184 aa)
	RRAGD	Ras-related GTP-binding protein D. (400 aa)
	RAB10	RAB10, member RAS oncogene family. (200 aa)
	RAP2C	Ras-related protein Rap-2c. (183 aa)
	RAB4A	Uncharacterized protein. (237 aa)
	RAB18	Uncharacterized protein. (274 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	RAB2A	Uncharacterized protein. (240 aa)
	RRAS	Ras-related protein R-Ras. (218 aa)
	RRAGC	Ras related GTP binding C. (399 aa)
	GNAI1	G protein subunit alpha i1. (422 aa)
	RAB9A	Ras-related protein Rab-9A. (201 aa)
	HRAS	Transforming protein p21. (189 aa)
	GNAT1	G protein subunit alpha i2. (350 aa)
	RIT1	Uncharacterized protein. (236 aa)
	SEPTIN12	Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
	RAB8B	RAB8B, member RAS oncogene family. (286 aa)
	ERAS	GTPase ERas. (233 aa)
	RAP2B	Uncharacterized protein. (183 aa)
	RHEBL1	Ras-like protein enriched in brain-like protein 1. (183 aa)
	UCP1	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
	RAB3B	RAB3B, member RAS oncogene family. (219 aa)
	ARL2	ADP-ribosylation factor-like protein 2 isoform 1; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	RAB17	RAB17, member RAS oncogene family. (238 aa)
	RERG	Ras-related and estrogen-regulated growth inhibitor isoform 1. (199 aa)
	MRAS	Uncharacterized protein. (214 aa)
	RAB42	RAB42, member RAS oncogene family. (218 aa)
	RASEF	RAS and EF-hand domain containing. (740 aa)
	ARF6	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (190 aa)
	GNAI3	Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
	TRIM23	E3 ubiquitin-protein ligase TRIM23 isoform alpha. (574 aa)
	MIEF1	Mitochondrial elongation factor 1. (478 aa)
	KRAS	KRAS proto-oncogene, GTPase. (412 aa)
	TMEM19	Transmembrane protein 19. (336 aa)
	RAB12	RAB12, member RAS oncogene family. (404 aa)
	RAB28	Uncharacterized protein. (366 aa)
	RAB21	RAB21, member RAS oncogene family. (263 aa)
	RAB14	Ras-related protein Rab-14. (215 aa)
	RAB27A	Uncharacterized protein. (321 aa)
	RAB8A	Ras-related protein Rab-8A. (207 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	RIT2	Ras-like protein expressed in neurons. (217 aa)
	RAP2A	Ras-related protein Rap-2a. (183 aa)
	RASL12	Ras-like protein family member 12. (266 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF6	RAB14	ENSMMUP00000077911	ENSMMUP00000073722	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Ras-related protein Rab-14.	0.447
ARF6	RAB18	ENSMMUP00000077911	ENSMMUP00000049239	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.595
ARF6	RAB21	ENSMMUP00000077911	ENSMMUP00000074375	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	RAB21, member RAS oncogene family.	0.519
ARF6	RAB22A	ENSMMUP00000077911	ENSMMUP00000057391	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	RAB22A, member RAS oncogene family.	0.516
ARF6	RAB27A	ENSMMUP00000077911	ENSMMUP00000073569	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.439
ARF6	RAB35	ENSMMUP00000077911	ENSMMUP00000061477	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.670
ARF6	RAB4A	ENSMMUP00000077911	ENSMMUP00000049795	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.446
ARL2	HRAS	ENSMMUP00000016165	ENSMMUP00000028522	ADP-ribosylation factor-like protein 2 isoform 1; Belongs to the small GTPase superfamily. Arf family.	Transforming protein p21.	0.440
ARL2	RALA	ENSMMUP00000016165	ENSMMUP00000068399	ADP-ribosylation factor-like protein 2 isoform 1; Belongs to the small GTPase superfamily. Arf family.	Ras-related protein Ral-A.	0.413
ARL3	RAB28	ENSMMUP00000065212	ENSMMUP00000074389	Uncharacterized protein.	Uncharacterized protein.	0.517
ARL3	RAB35	ENSMMUP00000065212	ENSMMUP00000061477	Uncharacterized protein.	Uncharacterized protein.	0.490
DYNC1LI1	RAB7A	ENSMMUP00000055901	ENSMMUP00000065506	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	RAB7A, member RAS oncogene family.	0.901
ENSMMUP00000064834	RAB14	ENSMMUP00000064834	ENSMMUP00000073722	Uncharacterized protein.	Ras-related protein Rab-14.	0.526
ENSMMUP00000064834	RAB18	ENSMMUP00000064834	ENSMMUP00000049239	Uncharacterized protein.	Uncharacterized protein.	0.439
ENSMMUP00000064834	RAB4A	ENSMMUP00000064834	ENSMMUP00000049795	Uncharacterized protein.	Uncharacterized protein.	0.468
ENSMMUP00000064834	RAB7A	ENSMMUP00000064834	ENSMMUP00000065506	Uncharacterized protein.	RAB7A, member RAS oncogene family.	0.597
ENSMMUP00000064834	RAB8A	ENSMMUP00000064834	ENSMMUP00000070643	Uncharacterized protein.	Ras-related protein Rab-8A.	0.427
ENSMMUP00000064834	RAB9A	ENSMMUP00000064834	ENSMMUP00000029777	Uncharacterized protein.	Ras-related protein Rab-9A.	0.517
ENSMMUP00000064834	RAB9B	ENSMMUP00000064834	ENSMMUP00000068711	Uncharacterized protein.	Uncharacterized protein.	0.447
ERAS	HRAS	ENSMMUP00000021640	ENSMMUP00000028522	GTPase ERas.	Transforming protein p21.	0.513