STRINGSTRING
PLXNA3 PLXNA3 EGR2 EGR2 CHRNB2 CHRNB2 SEMA3A SEMA3A TMEM126A TMEM126A SLC25A46 SLC25A46 AFG3L2 AFG3L2 HOXD3 HOXD3 PHOX2A PHOX2A HOXA3 HOXA3 DICER1 DICER1 SULF2 SULF2 HOXB2 HOXB2 DRGX DRGX TIFAB TIFAB ACKR3 ACKR3 GLI3 GLI3 PHOX2B PHOX2B NKX2-2 NKX2-2 NRTN NRTN ISL1 ISL1 FBXO45 FBXO45 CTNNB1 CTNNB1 EDN1 EDN1 PLXNA1 PLXNA1 BDNF BDNF TFAP2A TFAP2A TBX1 TBX1 ADARB1 ADARB1 RPL24 RPL24 ATP8B1 ATP8B1 ERBB3 ERBB3 CITED2 CITED2 EPHB2 EPHB2 ENSMMUP00000049472 ENSMMUP00000049472 EPHB1 EPHB1 NGF NGF ENSMMUP00000043582 ENSMMUP00000043582 CITED4 CITED4 NTF3 NTF3 LRIG1 LRIG1 SEMA3F SEMA3F POU4F1 POU4F1 NRP1 NRP1 EDNRA EDNRA PRKCG PRKCG GABRA5 GABRA5 SULF1 SULF1 TCIRG1 TCIRG1 VCAM1 VCAM1 HOXB1 HOXB1 NRP2 NRP2 LRIG2 LRIG2 CNGB1 CNGB1 GABRB2 GABRB2 COL25A1 COL25A1 RNF165 RNF165 SALL1 SALL1 NAV2 NAV2 SLITRK6 SLITRK6 NTF4 NTF4 RET RET ATOH7 ATOH7 SLC24A4 SLC24A4 HOXA1 HOXA1 DMD DMD NTRK1 NTRK1 CHD7 CHD7 ECE1 ECE1 PAX2 PAX2 EXT1 EXT1 LPAR1 LPAR1 SLC1A3 SLC1A3 SERPINE2 SERPINE2 PLXNA4 PLXNA4 NEUROG1 NEUROG1 DAG1 DAG1 MAFB MAFB SIX4 SIX4 NPTX1 NPTX1 H9H2Q7_MACMU H9H2Q7_MACMU LOC715685 LOC715685 ITGA4 ITGA4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLXNA3Plexin A3. (1892 aa)
EGR2Uncharacterized protein. (489 aa)
CHRNB2Neuronal acetylcholine receptor subunit beta-2. (502 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
TMEM126ATransmembrane protein 126A. (195 aa)
SLC25A46Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (800 aa)
HOXD3Homeobox D3. (432 aa)
PHOX2APaired like homeobox 2A. (284 aa)
HOXA3Homeobox A3. (443 aa)
DICER1Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (2011 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. (948 aa)
HOXB2Homeobox B2. (356 aa)
DRGXUncharacterized protein. (263 aa)
TIFABTIFA inhibitor. (204 aa)
ACKR3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (385 aa)
GLI3GLI family zinc finger 3. (1580 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
NKX2-2Homeobox domain-containing protein. (451 aa)
NRTNNeurturin preproprotein. (197 aa)
ISL1ISL LIM homeobox 1. (413 aa)
FBXO45Uncharacterized protein. (286 aa)
CTNNB1Catenin beta-1. (781 aa)
EDN1Preproendothelin-1. (211 aa)
PLXNA1Plexin A1. (2015 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
TFAP2ATranscription factor AP-2 alpha. (445 aa)
TBX1T-box transcription factor 1. (496 aa)
ADARB1Adenosine deaminase RNA specific B1. (783 aa)
RPL24TRASH domain-containing protein. (163 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3 isoform 1. (1342 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
EPHB2EPH receptor B2. (1082 aa)
ENSMMUP00000049472Uncharacterized protein. (370 aa)
EPHB1EPH receptor B1. (984 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (294 aa)
ENSMMUP00000043582TRASH domain-containing protein. (157 aa)
CITED4Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (232 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1088 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
POU4F1POU domain protein. (423 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
EDNRAUncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
SULF1Sulfatase 1. (1120 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (853 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
HOXB1Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily. (304 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (925 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1083 aa)
CNGB1Cyclic nucleotide-binding domain-containing protein. (1247 aa)
GABRB2Gamma-aminobutyric acid receptor subunit beta-2; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present [...] (512 aa)
COL25A1Collagen type XXV alpha 1 chain. (654 aa)
RNF165Ring finger protein 165. (346 aa)
SALL1Spalt like transcription factor 1. (1324 aa)
NAV2Neuron navigator 2. (2452 aa)
SLITRK6SLIT and NTRK like family member 6. (841 aa)
NTF4NGF domain-containing protein; Belongs to the NGF-beta family. (210 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
ATOH7Atonal bHLH transcription factor 7. (152 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
HOXA1Homeobox protein Hox-1F. (335 aa)
DMDUncharacterized protein. (3685 aa)
NTRK1Tyrosine-protein kinase receptor. (816 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2998 aa)
ECE1Endothelin converting enzyme 1. (780 aa)
PAX2Paired box 2. (418 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
SLC1A3Amino acid transporter. (549 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
PLXNA4Plexin A4. (1894 aa)
NEUROG1Neurogenin 1. (237 aa)
DAG1Dystroglycan preproprotein. (894 aa)
MAFBMAF bZIP transcription factor B. (329 aa)
SIX4SIX homeobox 4. (772 aa)
NPTX1Neuronal pentraxin-1. (432 aa)
H9H2Q7_MACMUG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (364 aa)
LOC715685Uncharacterized protein. (542 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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