STRINGSTRING
MYL3 MYL3 SYNPO2L SYNPO2L MYL12A MYL12A MTMR12 MTMR12 HRC HRC DNAJB6 DNAJB6 ENSMMUP00000078931 ENSMMUP00000078931 ATP2B4 ATP2B4 LRRC39 LRRC39 TRIM32 TRIM32 SPEGNB SPEGNB JPH1 JPH1 ENSMMUP00000076909 ENSMMUP00000076909 TPM4 TPM4 ASB2 ASB2 TNNC1 TNNC1 DUSP27 DUSP27 HSPB1 HSPB1 CFL2 CFL2 ANKRD40CL ANKRD40CL LMAN1 LMAN1 LOC721299 LOC721299 FKBP1B FKBP1B ANKRD40 ANKRD40 ABRA ABRA DNAJB7 DNAJB7 LOC699631 LOC699631 PARVB PARVB PPP2R5A PPP2R5A FHOD3 FHOD3 SMPX SMPX TNNI3 TNNI3 ENSMMUP00000068957 ENSMMUP00000068957 TMOD3 TMOD3 LOC708538 LOC708538 LRRC10 LRRC10 SH2B1 SH2B1 SYNE2 SYNE2 SYNC SYNC CSRP3 CSRP3 GGPS1 GGPS1 FBP2 FBP2 RTN2 RTN2 DST DST IGSF22 IGSF22 ANK1 ANK1 CASQ1 CASQ1 SORBS2 SORBS2 CTNNB1 CTNNB1 HABP4 HABP4 SCN8A SCN8A PDLIM1 PDLIM1 FLNB FLNB BAG3 BAG3 RYR2 RYR2 TIMP4 TIMP4 ARHGEF25 ARHGEF25 NRAP NRAP CAPN3 CAPN3 FRG1 FRG1 LMOD1 LMOD1 MYL7 MYL7 RYR1 RYR1 PDLIM7 PDLIM7 MYO18B MYO18B ANK3 ANK3 TNNI2 TNNI2 CHORDC1 CHORDC1 FLNC FLNC ANKRD1 ANKRD1 CAPZB CAPZB C3H7orf57 C3H7orf57 PDE4B PDE4B ANKRD23 ANKRD23 ILK ILK SMTNL2 SMTNL2 TMOD4 TMOD4 PGM5 PGM5 LMOD3 LMOD3 SYNPO2 SYNPO2 MYOZ2 MYOZ2 MYBPHL MYBPHL TTN TTN MYLK2 MYLK2 CORO1C CORO1C KAT2B KAT2B SMN1 SMN1 PPP3CA PPP3CA OBSL1 OBSL1 PDLIM3 PDLIM3 LDB3 LDB3 DCTN4 DCTN4 KCNN2 KCNN2 MYL2 MYL2 TMOD1 TMOD1 C10orf113 C10orf113 RYR3 RYR3 LRRC10B LRRC10B MYL1 MYL1 PARVA PARVA ADRA1A ADRA1A SLC2A1 SLC2A1 DCUN1D2 DCUN1D2 BIN1 BIN1 SCN1A SCN1A MMP2 MMP2 CACNA1D CACNA1D LOC100424620 LOC100424620 FRG1-2 FRG1-2 FHL3 FHL3 PSMA6 PSMA6 PVALEF PVALEF SIMC1 SIMC1 MYH7 MYH7 NOS1AP NOS1AP ACTN2 ACTN2 ACTN1 ACTN1 MYPN MYPN TNNI1 TNNI1 TMOD2 TMOD2 MYOM2 MYOM2 SPTBN1 SPTBN1 NBR1 NBR1 TNNC2 TNNC2 STUB1 STUB1 SMTNL1 SMTNL1 FERMT2 FERMT2 CMYA5 CMYA5 NEXN NEXN KCTD6 KCTD6 ACTN3 ACTN3 MYOZ1 MYOZ1 UNC45B UNC45B ANK2 ANK2 PALLD PALLD SQSTM1 SQSTM1 MYZAP MYZAP ALDOA ALDOA PLEC PLEC FBXO32 FBXO32 AKAP4 AKAP4 MYOM3 MYOM3 KCNA5 KCNA5 SRI SRI MTM1 MTM1 PDLIM5 PDLIM5 STK11 STK11 ACTA1 ACTA1 TRIM54 TRIM54 C10orf71 C10orf71 KLHL40 KLHL40 ABCC9 ABCC9 MYOZ3 MYOZ3 NDST1 NDST1 BBS5 BBS5 ITGB1BP2 ITGB1BP2 MYH1 MYH1 ANKRD2 ANKRD2 ANKRD60 ANKRD60 MYOM1 MYOM1 PPP1R12B PPP1R12B PPP1R12A PPP1R12A SYNE1 SYNE1 PAK1 PAK1 KRT19 KRT19 MYL4 MYL4 GLRX3 GLRX3 CSRP2 CSRP2 CALML5 CALML5 CACNA1S CACNA1S SLC4A1 SLC4A1 HOMER1 HOMER1 FHL2 FHL2 TNNT3 TNNT3 JPH2 JPH2 SCN5A SCN5A PPP3CB PPP3CB MYBPC3 MYBPC3 SLC8A1 SLC8A1 BMP10 BMP10 PDLIM4 PDLIM4 TRIM63 TRIM63 MYH4 MYH4 CAB39 CAB39 KY KY NEBL NEBL TPM3 TPM3 PYROXD1 PYROXD1 LMOD2 LMOD2 FBXL22 FBXL22 F7DJI7_MACMU F7DJI7_MACMU DMD DMD CACNA1C CACNA1C JUP JUP XIRP2 XIRP2 IGFN1 IGFN1 TNNT2 TNNT2 FLNA FLNA H9H3N9_MACMU H9H3N9_MACMU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYL3Myosin light chain 3. (254 aa)
SYNPO2LUncharacterized protein. (979 aa)
MYL12AUncharacterized protein. (232 aa)
MTMR12Myotubularin phosphatase domain-containing protein. (776 aa)
HRCHistidine rich calcium binding protein. (799 aa)
DNAJB6DnaJ heat shock protein family (Hsp40) member B6. (326 aa)
ENSMMUP00000078931Uncharacterized protein; Belongs to the tropomyosin family. (247 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
LRRC39Leucine rich repeat containing 39. (394 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
SPEGNBSPEG neighbor. (238 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
ENSMMUP00000076909Uncharacterized protein. (102 aa)
TPM4Tropomyosin alpha-4 chain isoform 1; Belongs to the tropomyosin family. (284 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (790 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (213 aa)
DUSP27Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (1164 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
ANKRD40CLANKRD40 C-terminal like. (114 aa)
LMAN1ER-Golgi intermediate compartment 53 kDa protein. (510 aa)
LOC721299Uncharacterized protein; Belongs to the actin family. (372 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
ANKRD40Ankyrin repeat domain 40. (365 aa)
ABRAActin binding Rho activating protein. (381 aa)
DNAJB7DnaJ heat shock protein family (Hsp40) member B7. (309 aa)
LOC699631Proteasome subunit alpha type. (206 aa)
PARVBParvin beta. (406 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
FHOD3Uncharacterized protein. (1655 aa)
SMPXStretch-responsive skeletal muscle protein. (88 aa)
TNNI3Troponin T1, slow skeletal type. (443 aa)
ENSMMUP00000068957Uncharacterized protein. (164 aa)
TMOD3Uncharacterized protein. (400 aa)
LOC708538Tudor domain-containing protein. (275 aa)
LRRC10Leucine-rich repeat-containing protein 10. (279 aa)
SH2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1087 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6909 aa)
SYNCSyncoilin, intermediate filament protein; Belongs to the intermediate filament family. (539 aa)
CSRP3Cysteine and glycine rich protein 3. (253 aa)
GGPS1Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (300 aa)
FBP2FBPase domain-containing protein; Belongs to the FBPase class 1 family. (345 aa)
RTN2Reticulon. (581 aa)
DSTDystonin. (7760 aa)
IGSF22Immunoglobulin superfamily member 22. (1326 aa)
ANK1Ankyrin 1. (2026 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (398 aa)
SORBS2Sorbin and SH3 domain containing 2. (1246 aa)
CTNNB1Catenin beta-1. (781 aa)
HABP4Hyaluronan binding protein 4. (414 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
PDLIM1PDZ and LIM domain 1. (330 aa)
FLNBFilamin B. (2633 aa)
BAG3Uncharacterized protein. (575 aa)
RYR2Ryanodine receptor 2. (4967 aa)
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)
ARHGEF25Rho guanine nucleotide exchange factor 25. (619 aa)
NRAPNebulin related anchoring protein. (1731 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (821 aa)
FRG1FSHD region gene 1. (258 aa)
LMOD1Leiomodin 1. (674 aa)
MYL7Myosin light chain 7. (251 aa)
RYR1Ryanodine receptor 1. (4928 aa)
PDLIM7PDZ and LIM domain 7. (508 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2565 aa)
ANK3Ankyrin 3. (4375 aa)
TNNI2Troponin I2, fast skeletal type. (182 aa)
CHORDC1Uncharacterized protein. (334 aa)
FLNCFilamin C. (2725 aa)
ANKRD1Ankyrin repeat domain 1. (318 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa)
C3H7orf57Chromosome 3 C7orf57 homolog. (323 aa)
PDE4BPhosphodiesterase. (736 aa)
ANKRD23Ankyrin repeat domain 23. (306 aa)
ILKIntegrin-linked protein kinase. (452 aa)
SMTNL2Smoothelin like 2. (461 aa)
TMOD4Tropomodulin 4. (345 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (530 aa)
LMOD3Leiomodin 3. (558 aa)
SYNPO2Synaptopodin 2. (1261 aa)
MYOZ2Myozenin 2. (277 aa)
MYBPHLMyosin binding protein H like. (354 aa)
TTNTitin. (32000 aa)
MYLK2Myosin light chain kinase 2. (603 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (527 aa)
KAT2BLysine acetyltransferase 2B. (866 aa)
SMN1Tudor domain-containing protein. (297 aa)
PPP3CASerine/threonine-protein phosphatase. (547 aa)
OBSL1Obscurin like 1. (1896 aa)
PDLIM3PDZ and LIM domain 3. (404 aa)
LDB3LIM domain binding 3. (732 aa)
DCTN4Uncharacterized protein. (467 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (858 aa)
MYL2Myosin light chain 2. (166 aa)
TMOD1Uncharacterized protein. (386 aa)
C10orf113Chromosome 10 open reading frame 113. (155 aa)
RYR3Ryanodine receptor 3. (4870 aa)
LRRC10BLeucine rich repeat containing 10B. (292 aa)
MYL1Myosin light chain 1. (237 aa)
PARVAParvin alpha. (372 aa)
ADRA1AAdrenoceptor alpha 1A. (445 aa)
SLC2A1MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (669 aa)
DCUN1D2Defective in cullin neddylation 1 domain containing 2. (1866 aa)
BIN1Bridging integrator 1. (668 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2008 aa)
MMP272 kDa type IV collagenase isoform a preproprotein. (660 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
LOC100424620SMN domain-containing protein. (87 aa)
FRG1-2Uncharacterized protein. (223 aa)
FHL3Four and a half LIM domains protein 3. (280 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
SIMC1SUMO interacting motifs containing 1. (933 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
NOS1APPID domain-containing protein. (695 aa)
ACTN2Actinin alpha 2. (894 aa)
ACTN1Actinin alpha 1. (914 aa)
MYPNMyopalladin. (1346 aa)
TNNI1Uncharacterized protein. (187 aa)
TMOD2Uncharacterized protein. (359 aa)
MYOM2Myomesin 2. (1490 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
NBR1NBR1 autophagy cargo receptor. (980 aa)
TNNC2Troponin C2, fast skeletal type. (345 aa)
STUB1STIP1 homology and U-box containing protein 1. (539 aa)
SMTNL1Smoothelin like 1. (512 aa)
FERMT2PH domain-containing protein. (698 aa)
CMYA5Cardiomyopathy associated 5. (3969 aa)
NEXNNexilin F-actin binding protein. (675 aa)
KCTD6Potassium channel tetramerization domain containing 6. (263 aa)
ACTN3Uncharacterized protein. (942 aa)
MYOZ1Myozenin 1. (299 aa)
UNC45BUnc-45 myosin chaperone B. (929 aa)
ANK2Ankyrin 2. (4045 aa)
PALLDPalladin, cytoskeletal associated protein. (1400 aa)
SQSTM1Sequestosome 1. (440 aa)
MYZAPGRINL1A complex locus 1. (850 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (418 aa)
PLECPlectin. (4862 aa)
FBXO32F-box only protein 32 isoform 1. (355 aa)
AKAP4A-kinase anchoring protein 4. (845 aa)
MYOM3Myomesin 3. (1437 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
SRISorcin isoform a. (198 aa)
MTM1Myotubularin. (603 aa)
PDLIM5PDZ and LIM domain 5. (686 aa)
STK11Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (433 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
TRIM54Tripartite motif containing 54. (402 aa)
C10orf71Chromosome 10 open reading frame 71. (1435 aa)
KLHL40Kelch like family member 40. (621 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
MYOZ3Uncharacterized protein. (251 aa)
NDST1Uncharacterized protein. (1141 aa)
BBS5Kelch like family member 41. (606 aa)
ITGB1BP2Integrin subunit beta 1 binding protein 2. (348 aa)
MYH1Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
ANKRD2Ankyrin repeat domain 2. (532 aa)
ANKRD60Ankyrin repeat domain 60. (344 aa)
MYOM1Myomesin 1. (1673 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1090 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
SYNE1Spectrin repeat containing nuclear envelope protein 1. (8797 aa)
PAK1Non-specific serine/threonine protein kinase. (575 aa)
KRT19Keratin, type I cytoskeletal 19; Belongs to the intermediate filament family. (400 aa)
MYL4Myosin light chain 4. (195 aa)
GLRX3Glutaredoxin 3. (335 aa)
CSRP2Cysteine and glycine-rich protein 2. (193 aa)
CALML5Calmodulin-like protein 5. (146 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
SLC4A1Anion exchange protein. (914 aa)
HOMER1Homer scaffold protein 1. (374 aa)
FHL2Four and a half LIM domains 2. (396 aa)
TNNT3Troponin T3, fast skeletal type. (289 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
MYBPC3Myosin binding protein C, cardiac. (1274 aa)
SLC8A1J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
PDLIM4PDZ and LIM domain protein 4 isoform 1. (330 aa)
TRIM63E3 ubiquitin-protein ligase TRIM63. (353 aa)
MYH4Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
CAB39Calcium-binding protein 39. (341 aa)
KYKyphoscoliosis peptidase. (720 aa)
NEBLNebulette. (1028 aa)
TPM3Tropomyosin 3; Belongs to the tropomyosin family. (285 aa)
PYROXD1Pyridine nucleotide-disulphide oxidoreductase domain 1. (500 aa)
LMOD2Leiomodin 2. (547 aa)
FBXL22F-box and leucine rich repeat protein 22. (226 aa)
F7DJI7_MACMUUncharacterized protein. (445 aa)
DMDUncharacterized protein. (3685 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
JUPUncharacterized protein. (744 aa)
XIRP2Xin actin binding repeat containing 2. (3550 aa)
IGFN1Uncharacterized protein. (1282 aa)
TNNT2Troponin T2, cardiac type. (302 aa)
FLNAFilamin-A isoform 2. (2647 aa)
H9H3N9_MACMUUncharacterized protein; Belongs to the tropomyosin family. (312 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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