STRINGSTRING
ITGA4 ITGA4 RC3H1 RC3H1 RABL3 RABL3 FZD8 FZD8 IL9 IL9 CCR7 CCR7 TRAF3IP2 TRAF3IP2 FOXP1 FOXP1 IL4 IL4 PIK3R2 PIK3R2 LEPR LEPR STAT5B STAT5B CD8A CD8A BATF BATF BAX BAX ATM ATM LEP LEP PLCG2 PLCG2 CCR6 CCR6 PTPRJ PTPRJ PSMB11 PSMB11 HDAC4 HDAC4 FBXO7 FBXO7 CD19 CD19 GATA3 GATA3 ITFG2 ITFG2 DNAJA3 DNAJA3 SOX13 SOX13 FOXP3 FOXP3 TP53 TP53 BLNK BLNK CDK6 CDK6 CD74 CD74 IL18R1 IL18R1 PKNOX1 PKNOX1 TSC1 TSC1 YY1AP1 YY1AP1 MERTK MERTK TOX TOX JAK3 JAK3 ITK ITK SLAMF8 SLAMF8 PBX1 PBX1 PIK3R1 PIK3R1 CHD7 CHD7 HHEX HHEX RORC RORC GPR183 GPR183 NTRK1 NTRK1 NCAPH2 NCAPH2 LMBR1L LMBR1L ATP7A ATP7A ADAM17 ADAM17 LOC712274 LOC712274 CR2 CR2 CLEC4D CLEC4D CLEC4E CLEC4E TYRO3 TYRO3 RELB RELB MALT1 MALT1 NRARP NRARP SOX4 SOX4 THEMIS THEMIS IL15RA IL15RA PRKDC PRKDC ADGRG3 ADGRG3 WNT1 WNT1 PPP3CB PPP3CB SLAMF1 SLAMF1 RSAD2 RSAD2 LFNG LFNG SPN SPN PTGER4 PTGER4 F7HDN1_MACMU F7HDN1_MACMU CD3D CD3D IL2RG IL2RG LRRC8A LRRC8A RAG2 RAG2 NKX2-3 NKX2-3 SYVN1 SYVN1 IL15 IL15 AICDA AICDA PTK2B PTK2B GPR89A GPR89A ATG5 ATG5 TSHR TSHR DLL1 DLL1 ZAP70 ZAP70 SP3 SP3 C17orf99 C17orf99 FOXN1 FOXN1 STK11 STK11 VCAM1 VCAM1 IL6R IL6R TCIRG1 TCIRG1 CCR9 CCR9 LOC694631 LOC694631 TGFB1 TGFB1 ENTPD7 ENTPD7 RIPK2 RIPK2 SRF SRF TCF7 TCF7 IKZF3 IKZF3 TNFSF13B TNFSF13B FLT3 FLT3 MSH2 MSH2 PATZ1 PATZ1 ADA ADA LY9 LY9 SLAMF6 SLAMF6 SEMA4A SEMA4A ZBTB7B ZBTB7B CTSL CTSL CD40LG CD40LG DOCK11 DOCK11 BTK BTK PLA2G2D PLA2G2D FZD7 FZD7 AXL AXL POU2AF1 POU2AF1 LOC710751 LOC710751 PAX5 PAX5 STAT3 STAT3 LEF1 LEF1 LYL1 LYL1 LCK LCK BRAF BRAF ENSMMUP00000044881 ENSMMUP00000044881 RHOA RHOA IL7R IL7R IRF1 IRF1 NOTCH2 NOTCH2 FZD9 FZD9 RORA RORA ZFP36L1 ZFP36L1 ATF2 ATF2 IL6 IL6 FUT7 FUT7 KAT7 KAT7 GPS2 GPS2 CMTM7 CMTM7 CD79B CD79B DCAF1 DCAF1 MFNG MFNG IL7 IL7 PTPN22 PTPN22 ABL1 ABL1 PTPRC PTPRC PGBD4 PGBD4 ENSMMUP00000054262 ENSMMUP00000054262 ARMC5 ARMC5 CDH17 CDH17 GIMAP1 GIMAP1 CD79A CD79A LOC100428304 LOC100428304 ZBTB1 ZBTB1 TESPA1 TESPA1 JMJD6 JMJD6 WNT10B WNT10B KLF6 KLF6 RC3H2 RC3H2 VAV1 VAV1 PIK3R3 PIK3R3 EZH2 EZH2 TNFSF8 TNFSF8 KIT KIT IFNK IFNK CARD11 CARD11 FADD FADD LOC710568 LOC710568 IFNA14 IFNA14 STAT6 STAT6 IRF4 IRF4 ITM2A ITM2A LOC114669853 LOC114669853 CD3E CD3E TBX21 TBX21 ZBTB7A ZBTB7A CTNNB1 CTNNB1 IFNW1 IFNW1 TCF3 TCF3 IKZF1 IKZF1 GPR18 GPR18 SYK SYK IL21 IL21 ANXA1 ANXA1 ERBB2 ERBB2 DOCK10 DOCK10 LOC114675515 LOC114675515 CEBPG CEBPG CD28 CD28 SHH SHH IRF2BP2 IRF2BP2 HECTD1 HECTD1 LY6D LY6D DLL4 DLL4 PAX1 PAX1 PTPN2 PTPN2 MS4A1 MS4A1 PRR7 PRR7 IRF8 IRF8 GLI3 GLI3 IFNA6 IFNA6 BAK1 BAK1 WNT4 WNT4 PLCL2 PLCL2 TPD52 TPD52 ZFP36L2 ZFP36L2 PIK3CD PIK3CD XRCC4 XRCC4 LIG4 LIG4 CD4 CD4 BCL2 BCL2 CLEC4G CLEC4G RUNX2 RUNX2 DNAJB9 DNAJB9 CBFB CBFB ITPKB ITPKB CRACR2A CRACR2A EOMES EOMES IFNA10 IFNA10 AIRE AIRE CD83 CD83 IFNA8 IFNA8 TUSC2 TUSC2 ZFPM1 ZFPM1 MTOR MTOR RAG1 RAG1 LOC705334 LOC705334 TMEM98 TMEM98 JAG2 JAG2 HDAC9 HDAC9 ST3GAL1 ST3GAL1 DOCK2 DOCK2 B2M B2M NFAM1 NFAM1 EP300 EP300 ENSMMUP00000077416 ENSMMUP00000077416 IFNA13 IFNA13 EGR1 EGR1 BCL3 BCL3 HLX HLX FZD5 FZD5 PREX1 PREX1 RHOH RHOH BCL11B BCL11B BCL6 BCL6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
RC3H1Ring finger and CCCH-type domains 1. (1133 aa)
RABL3Uncharacterized protein. (268 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (693 aa)
IL9Interleukin 9. (144 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
TRAF3IP2SEFIR domain-containing protein. (572 aa)
FOXP1Fork-head domain-containing protein. (695 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (153 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
LEPRLeptin receptor; Receptor for hormone LEP/leptin (By similarity). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductiv [...] (1163 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
CD8ACD8a molecule. (269 aa)
BATFBasic leucine zipper ATF-like transcription factor. (137 aa)
BAXUncharacterized protein. (279 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (379 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1336 aa)
PSMB11Proteasome subunit beta. (243 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1084 aa)
FBXO7F-box only protein 7 isoform 1. (522 aa)
CD19CD19 molecule. (557 aa)
GATA3GATA binding protein 3. (444 aa)
ITFG2Integrin alpha FG-GAP repeat containing 2. (472 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
SOX13SRY-box 13. (621 aa)
FOXP3Forkhead box P3. (539 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (433 aa)
BLNKB cell linker. (559 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (335 aa)
CD74HLA class II histocompatibility antigen gamma chain isoform a. (294 aa)
IL18R1Interleukin 18 receptor 1. (540 aa)
PKNOX1PBX/knotted 1 homeobox 1. (503 aa)
TSC1TSC complex subunit 1. (1164 aa)
YY1AP1Myb-like domain-containing protein. (2243 aa)
MERTKMER proto-oncogene, tyrosine kinase. (1232 aa)
TOXThymocyte selection associated high mobility group box. (526 aa)
JAK3Janus kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (602 aa)
ITKTyrosine-protein kinase. (620 aa)
SLAMF8SLAM family member 8. (285 aa)
PBX1Pre-B-cell leukemia transcription factor 1 isoform 1. (430 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2998 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
RORCRAR related orphan receptor C. (518 aa)
GPR183G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)
NTRK1Tyrosine-protein kinase receptor. (816 aa)
NCAPH2Condensin-2 complex subunit H2 isoform 2. (611 aa)
LMBR1LUncharacterized protein; Belongs to the LIMR family. (489 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
ADAM17Disintegrin and metalloproteinase domain-containing protein 17 preproprotein. (824 aa)
LOC71227440S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (218 aa)
CR2Complement C3d receptor 2. (1091 aa)
CLEC4DC-type lectin domain family 4 member D. (215 aa)
CLEC4EC-type lectin domain family 4 member E. (274 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3. (890 aa)
RELBRELB proto-oncogene, NF-kB subunit. (574 aa)
MALT1MALT1 paracaspase. (824 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
SOX4Transcription factor SOX. (467 aa)
THEMISThymocyte selection associated. (680 aa)
IL15RAInterleukin 15 receptor subunit alpha. (272 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa)
ADGRG3Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (577 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (356 aa)
RSAD2Radical S-adenosyl methionine domain-containing protein 2. (360 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (379 aa)
SPNSialophorin. (547 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (490 aa)
F7HDN1_MACMUIG domain-containing protein. (248 aa)
CD3DIg_4 domain-containing protein. (171 aa)
IL2RGCytokine receptor common subunit gamma. (369 aa)
LRRC8ALeucine-rich repeat-containing protein 8A. (810 aa)
RAG2Recombination activating 2. (532 aa)
NKX2-3NK2 homeobox 3. (364 aa)
SYVN1E3 ubiquitin-protein ligase synoviolin isoform b. (617 aa)
IL15Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity); Belongs to the IL-15/IL-21 family. (162 aa)
AICDAActivation induced cytidine deaminase. (198 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
GPR89AGolgi pH regulator B. (455 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (317 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
SP3Sp3 transcription factor. (796 aa)
C17orf99Chromosome 17 open reading frame 99. (265 aa)
FOXN1Forkhead box N1. (648 aa)
STK11Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (433 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
IL6RInterleukin 6 receptor. (536 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (853 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
LOC694631Uncharacterized protein. (190 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
SRFSerum response factor. (508 aa)
TCF7Transcription factor 7. (571 aa)
IKZF3Zinc finger protein Aiolos isoform 1. (509 aa)
TNFSF13BTNF-and APOL-related leukocyte expressed ligand 1; Belongs to the tumor necrosis factor family. (285 aa)
FLT3Fms related tyrosine kinase 3. (904 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (933 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
ADAAdenosine deaminase. (390 aa)
LY9Uncharacterized protein. (208 aa)
SLAMF6SLAM family member 6. (339 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (636 aa)
CTSLCathepsin L; Belongs to the peptidase C1 family. (333 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2086 aa)
BTKTyrosine-protein kinase. (659 aa)
PLA2G2DPhospholipase A(2). (161 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (597 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
POU2AF1POU class 2 homeobox associating factor 1. (275 aa)
LOC710751Uncharacterized protein. (189 aa)
PAX5Paired box 5. (407 aa)
STAT3Signal transducer and activator of transcription. (871 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
LYL1LYL1 basic helix-loop-helix family member. (293 aa)
LCKTyrosine-protein kinase. (567 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
ENSMMUP00000044881A_deaminase domain-containing protein. (74 aa)
RHOARas homolog family member A. (209 aa)
IL7RInterleukin 7 receptor. (459 aa)
IRF1Interferon regulatory factor. (325 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform 1 preproprotein. (2471 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
RORARAR related orphan receptor A. (555 aa)
ZFP36L1ZFP36 ring finger protein like 1. (344 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (266 aa)
FUT7Fucosyltransferase 7. (342 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
GPS2G protein pathway suppressor 2. (327 aa)
CMTM7MARVEL domain-containing protein. (185 aa)
CD79BB-cell antigen receptor complex-associated protein beta chain isoform 3. (231 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1576 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
IL7Uncharacterized protein. (184 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (813 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
PGBD4PiggyBac transposable element derived 4. (583 aa)
ENSMMUP00000054262Uncharacterized protein; Belongs to the peptidase C1 family. (333 aa)
ARMC5Armadillo repeat containing 5. (1030 aa)
CDH17Cadherin 17. (832 aa)
GIMAP1AIG1-type G domain-containing protein. (306 aa)
CD79ACD79a molecule. (225 aa)
LOC100428304AIG1-type G domain-containing protein. (274 aa)
ZBTB1Zinc finger and BTB domain containing 1. (771 aa)
TESPA1KRAP_IP3R_bind domain-containing protein. (521 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (436 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
KLF6Krueppel-like factor 6 isoform A. (283 aa)
RC3H2RING finger and CCCH-type zinc finger domain-containing protein 2 isoform 1. (1191 aa)
VAV1Vav guanine nucleotide exchange factor 1. (928 aa)
PIK3R3Uncharacterized protein. (507 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (832 aa)
TNFSF8Tumor necrosis factor ligand superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
IFNKInterferon kappa. (207 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
LOC710568Interferon alpha 16. (189 aa)
IFNA14Interferon alpha 14. (189 aa)
STAT6Signal transducer and activator of transcription. (902 aa)
IRF4Interferon regulatory factor 4 isoform 1. (451 aa)
ITM2AIntegral membrane protein 2A. (342 aa)
LOC114669853Tyrosine-protein kinase. (1125 aa)
CD3ECD3e molecule. (217 aa)
TBX21T-box transcription factor 21. (539 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (692 aa)
CTNNB1Catenin beta-1. (781 aa)
IFNW1Interferon alpha-II-1. (195 aa)
TCF3Transcription factor 3. (654 aa)
IKZF1IKAROS family zinc finger 1. (543 aa)
GPR18G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (300 aa)
SYKTyrosine-protein kinase. (635 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
ANXA1Annexin. (367 aa)
ERBB2Receptor protein-tyrosine kinase. (1437 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2370 aa)
LOC114675515Uncharacterized protein. (152 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (150 aa)
CD28T-cell-specific surface glycoprotein CD28. (220 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
IRF2BP2Interferon regulatory factor 2-binding protein 2 isoform A. (587 aa)
HECTD1E3 ubiquitin-protein ligase HECTD1. (2610 aa)
LY6DLymphocyte antigen 6 family member D. (157 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
PAX1Paired box 1. (535 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (415 aa)
MS4A1Membrane spanning 4-domains A1. (297 aa)
PRR7Proline rich 7, synaptic. (276 aa)
IRF8IRF tryptophan pentad repeat domain-containing protein. (436 aa)
GLI3GLI family zinc finger 3. (1580 aa)
IFNA6Interferon alpha-6. (189 aa)
BAK1Uncharacterized protein. (261 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
PLCL2Phosphoinositide phospholipase C. (1127 aa)
TPD52Tumor protein D52. (360 aa)
ZFP36L2Zinc finger protein 36, C3H1 type-like 2. (492 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
XRCC4X-ray repair cross complementing 4. (334 aa)
LIG4DNA ligase. (911 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
BCL2BCL2 apoptosis regulator. (241 aa)
CLEC4GC-type lectin domain family 4 member G. (293 aa)
RUNX2RUNX family transcription factor 2. (647 aa)
DNAJB9DnaJ homolog subfamily B member 9. (222 aa)
CBFBCore-binding factor subunit beta isoform 1. (187 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa)
CRACR2ACalcium release activated channel regulator 2A. (731 aa)
EOMESEomesodermin. (703 aa)
IFNA10Uncharacterized protein. (189 aa)
AIREAutoimmune regulator. (614 aa)
CD83CD83 antigen isoform a. (205 aa)
IFNA8Interferon alpha-8. (189 aa)
TUSC2Tumor suppressor candidate 2. (110 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1024 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1081 aa)
LOC705334Uncharacterized protein. (205 aa)
TMEM98Transmembrane protein 98. (226 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1290 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1086 aa)
ST3GAL1CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (340 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1867 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (119 aa)
NFAM1NFAT activating protein with ITAM motif 1. (271 aa)
EP300Histone acetyltransferase p300. (2414 aa)
ENSMMUP00000077416Uncharacterized protein. (113 aa)
IFNA13Uncharacterized protein. (190 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (545 aa)
BCL3BCL3 transcription coactivator. (454 aa)
HLXH2.0 like homeobox. (495 aa)
FZD5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1661 aa)
RHOHRho-related GTP-binding protein RhoH. (191 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
BCL6Uncharacterized protein. (735 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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