(30 nodes) Structural constituent of skin epidermis network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOR	Uncharacterized protein. (337 aa)
	KRT73	Keratin 73; Belongs to the intermediate filament family. (540 aa)
	KRT2	Keratin 2; Belongs to the intermediate filament family. (647 aa)
	KRT5	Keratin 5; Belongs to the intermediate filament family. (624 aa)
	KRT8	IF rod domain-containing protein; Belongs to the intermediate filament family. (467 aa)
	KRT78	Keratin 78; Belongs to the intermediate filament family. (514 aa)
	KRT86	Type II hair keratin Hb6; Belongs to the intermediate filament family. (486 aa)
	PKP1	Plakophilin 1. (747 aa)
	KRT7	Keratin, type II cytoskeletal 7; Belongs to the intermediate filament family. (469 aa)
	KRT71	Keratin 71; Belongs to the intermediate filament family. (525 aa)
	KRT76	Keratin 76; Belongs to the intermediate filament family. (637 aa)
	KRT3	Keratin 3; Belongs to the intermediate filament family. (617 aa)
	KRT4	Keratin 4; Belongs to the intermediate filament family. (520 aa)
	KRT79	Keratin 79; Belongs to the intermediate filament family. (528 aa)
	LOC100424162	IF rod domain-containing protein; Belongs to the intermediate filament family. (564 aa)
	KRT1	Cytokeratin-1; Belongs to the intermediate filament family. (636 aa)
	KRT81	Keratin 81; Belongs to the intermediate filament family. (505 aa)
	KRT84	Keratin 84; Belongs to the intermediate filament family. (600 aa)
	KRT82	Keratin 82; Belongs to the intermediate filament family. (513 aa)
	KRT75	Keratin 75; Belongs to the intermediate filament family. (551 aa)
	KRT36	Keratin 36; Belongs to the intermediate filament family. (491 aa)
	LOC703076	Uncharacterized protein. (187 aa)
	KRTAP1-4	Keratin associated protein 1-4. (121 aa)
	LOC106994039	Uncharacterized protein. (177 aa)
	KRT85	Keratin 85; Belongs to the intermediate filament family. (507 aa)
	ENSMMUP00000079277	IF rod domain-containing protein; Belongs to the intermediate filament family. (467 aa)
	PI3	Peptidase inhibitor 3. (117 aa)
	KRT80	Keratin 80; Belongs to the intermediate filament family. (497 aa)
	KRT77	Keratin 77; Belongs to the intermediate filament family. (579 aa)
	KRT74	Keratin 74; Belongs to the intermediate filament family. (529 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMMUP00000079277	KRT7	ENSMMUP00000079277	ENSMMUP00000018913	IF rod domain-containing protein; Belongs to the intermediate filament family.	Keratin, type II cytoskeletal 7; Belongs to the intermediate filament family.	0.500
KRT1	KRT2	ENSMMUP00000022305	ENSMMUP00000003083	Cytokeratin-1; Belongs to the intermediate filament family.	Keratin 2; Belongs to the intermediate filament family.	0.672
KRT1	KRT3	ENSMMUP00000022305	ENSMMUP00000019638	Cytokeratin-1; Belongs to the intermediate filament family.	Keratin 3; Belongs to the intermediate filament family.	0.512
KRT1	KRT5	ENSMMUP00000022305	ENSMMUP00000003320	Cytokeratin-1; Belongs to the intermediate filament family.	Keratin 5; Belongs to the intermediate filament family.	0.608
KRT1	KRT77	ENSMMUP00000022305	ENSMMUP00000056485	Cytokeratin-1; Belongs to the intermediate filament family.	Keratin 77; Belongs to the intermediate filament family.	0.517
KRT1	LOR	ENSMMUP00000022305	ENSMMUP00000046492	Cytokeratin-1; Belongs to the intermediate filament family.	Uncharacterized protein.	0.589
KRT2	KRT1	ENSMMUP00000003083	ENSMMUP00000022305	Keratin 2; Belongs to the intermediate filament family.	Cytokeratin-1; Belongs to the intermediate filament family.	0.672
KRT2	KRT5	ENSMMUP00000003083	ENSMMUP00000003320	Keratin 2; Belongs to the intermediate filament family.	Keratin 5; Belongs to the intermediate filament family.	0.561
KRT2	KRT77	ENSMMUP00000003083	ENSMMUP00000056485	Keratin 2; Belongs to the intermediate filament family.	Keratin 77; Belongs to the intermediate filament family.	0.493
KRT2	KRT79	ENSMMUP00000003083	ENSMMUP00000019644	Keratin 2; Belongs to the intermediate filament family.	Keratin 79; Belongs to the intermediate filament family.	0.539
KRT2	LOR	ENSMMUP00000003083	ENSMMUP00000046492	Keratin 2; Belongs to the intermediate filament family.	Uncharacterized protein.	0.451
KRT3	KRT1	ENSMMUP00000019638	ENSMMUP00000022305	Keratin 3; Belongs to the intermediate filament family.	Cytokeratin-1; Belongs to the intermediate filament family.	0.512
KRT3	KRT8	ENSMMUP00000019638	ENSMMUP00000005910	Keratin 3; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.469
KRT36	KRT80	ENSMMUP00000024527	ENSMMUP00000077157	Keratin 36; Belongs to the intermediate filament family.	Keratin 80; Belongs to the intermediate filament family.	0.428
KRT5	KRT1	ENSMMUP00000003320	ENSMMUP00000022305	Keratin 5; Belongs to the intermediate filament family.	Cytokeratin-1; Belongs to the intermediate filament family.	0.608
KRT5	KRT2	ENSMMUP00000003320	ENSMMUP00000003083	Keratin 5; Belongs to the intermediate filament family.	Keratin 2; Belongs to the intermediate filament family.	0.561
KRT5	KRT79	ENSMMUP00000003320	ENSMMUP00000019644	Keratin 5; Belongs to the intermediate filament family.	Keratin 79; Belongs to the intermediate filament family.	0.413
KRT5	LOR	ENSMMUP00000003320	ENSMMUP00000046492	Keratin 5; Belongs to the intermediate filament family.	Uncharacterized protein.	0.461
KRT5	PKP1	ENSMMUP00000003320	ENSMMUP00000017756	Keratin 5; Belongs to the intermediate filament family.	Plakophilin 1.	0.613
KRT7	ENSMMUP00000079277	ENSMMUP00000018913	ENSMMUP00000079277	Keratin, type II cytoskeletal 7; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.500