STRINGSTRING
NHLRC1 NHLRC1 AXIN1 AXIN1 BMI1 BMI1 CDC20B CDC20B MAPK9 MAPK9 RASSF5 RASSF5 HSPBP1 HSPBP1 ARRDC3 ARRDC3 FBXO4 FBXO4 AMER1 AMER1 F7DC82_MACMU F7DC82_MACMU HSPA5 HSPA5 SPRTN SPRTN TBC1D7 TBC1D7 BCL10 BCL10 CDC14B CDC14B HUWE1 HUWE1 FBXO33 FBXO33 DNAJA3 DNAJA3 PTEN PTEN RCHY1 RCHY1 LOC106996191 LOC106996191 GABARAP GABARAP SEPTIN4 SEPTIN4 FANCI FANCI UBE2V2 UBE2V2 TRIB3 TRIB3 WFS1 WFS1 CAV1 CAV1 MALT1 MALT1 NPM1 NPM1 LRRK2 LRRK2 UBE2S UBE2S FANCM FANCM PLK1 PLK1 MTA1 MTA1 ANGPT1 ANGPT1 NMI NMI CISD1 CISD1 FZR1 FZR1 PRKN PRKN KLHL40 KLHL40 PEF1 PEF1 RIPK2 RIPK2 RNF111 RNF111 HDAC3 HDAC3 BRCA1 BRCA1 RNF180 RNF180 PHF23 PHF23 COMMD1 COMMD1 CUL3 CUL3 NDUFB6 NDUFB6 LOC713290 LOC713290 PRICKLE1 PRICKLE1 CDC20 CDC20 PSMD10 PSMD10 F7CL83_MACMU F7CL83_MACMU PAXIP1 PAXIP1 DDX3X DDX3X STUB1 STUB1 DCUN1D4 DCUN1D4 SPHK1 SPHK1 FBXW7 FBXW7 NOD2 NOD2 ENSMMUP00000048641 ENSMMUP00000048641 DERL1 DERL1 MYCBP2 MYCBP2 PTTG1IP PTTG1IP UBE2L3 UBE2L3 BTRC BTRC SEPTIN4-2 SEPTIN4-2 UBE2N UBE2N PINK1 PINK1 PTPN22 PTPN22 KDM1A KDM1A SKP1-2 SKP1-2 RPS2 RPS2 RBX1 RBX1 DCUN1D1 DCUN1D1 AIMP2 AIMP2 ENSMMUP00000058534 ENSMMUP00000058534 UBE3A UBE3A SKP2 SKP2 LOC702827 LOC702827 DDX3Y DDX3Y RASSF1 RASSF1 ENSMMUP00000061414 ENSMMUP00000061414 SFXN2 SFXN2 XIAP XIAP BIRC7 BIRC7 SPSB4 SPSB4 SMAD7 SMAD7 ENSMMUP00000064139 ENSMMUP00000064139 EGK_08539 EGK_08539 MASTL MASTL ENSMMUP00000067414 ENSMMUP00000067414 ENSMMUP00000067677 ENSMMUP00000067677 CDK5RAP3 CDK5RAP3 BIRC3 BIRC3 NDFIP2 NDFIP2 MARCHF7 MARCHF7 CBLB CBLB PELI1 PELI1 TSPYL5 TSPYL5 ENSMMUP00000072883 ENSMMUP00000072883 CRY1 CRY1 FBXW9 FBXW9 BIRC2 BIRC2 PIN1 PIN1 DNAJB2 DNAJB2 NDFIP1 NDFIP1 ARRDC4 ARRDC4 INAVA INAVA ENSMMUP00000081054 ENSMMUP00000081054
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (395 aa)
AXIN1Axin 1. (867 aa)
BMI1RING-type domain-containing protein. (469 aa)
CDC20BCell division cycle 20B. (518 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
RASSF5Ras association domain family member 5. (418 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (377 aa)
ARRDC3TBP-2-like inducible membrane protein. (414 aa)
FBXO4F-box protein 4. (490 aa)
AMER1APC membrane recruitment protein 1. (1136 aa)
F7DC82_MACMUUncharacterized protein. (293 aa)
HSPA578 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family. (654 aa)
SPRTNSprT-like N-terminal domain. (492 aa)
TBC1D7TBC1 domain family member 7. (293 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
CDC14BCell division cycle 14B. (498 aa)
HUWE1E3 ubiquitin-protein ligase HUWE1. (4374 aa)
FBXO33F-box protein 33. (552 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
PTENUncharacterized protein. (589 aa)
RCHY1RING finger and CHY zinc finger domain-containing protein 1 isoform 1. (261 aa)
LOC10699619140S ribosomal protein S4; Belongs to the universal ribosomal protein uS5 family. (293 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
SEPTIN4Septin 4. (569 aa)
FANCIFA complementation group I. (1328 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
CAV1Caveolin 1. (303 aa)
MALT1MALT1 paracaspase. (824 aa)
NPM1Nucleophosmin isoform 1. (294 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
UBE2SUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
FANCMFA complementation group M. (2050 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
MTA1Metastasis associated 1. (726 aa)
ANGPT1Angiopoietin-1 isoform 1. (498 aa)
NMIN-myc and STAT interactor. (307 aa)
CISD1UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
KLHL40Kelch like family member 40. (621 aa)
PEF1Uncharacterized protein. (283 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
RNF111Ring finger protein 111. (1041 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1884 aa)
RNF180Ring finger protein 180. (592 aa)
PHF23PDH-containing protein JUNE-1. (403 aa)
COMMD1Copper metabolism domain containing 1. (190 aa)
CUL3Cullin-3; Belongs to the cullin family. (768 aa)
NDUFB6RING-type domain-containing protein. (1085 aa)
LOC713290Uncharacterized protein. (702 aa)
PRICKLE1Prickle planar cell polarity protein 1. (848 aa)
CDC20Cell division cycle protein 20 homolog. (499 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (253 aa)
F7CL83_MACMUS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (254 aa)
PAXIP1PAX interacting protein 1. (1154 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa)
STUB1STIP1 homology and U-box containing protein 1. (539 aa)
DCUN1D4DCN1-like protein. (398 aa)
SPHK1Sphingosine kinase 1. (470 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform 1. (707 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1044 aa)
ENSMMUP00000048641Uncharacterized protein. (258 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (280 aa)
MYCBP2MYC binding protein 2. (4682 aa)
PTTG1IPPituitary tumor-transforming gene 1 protein-interacting protein. (180 aa)
UBE2L3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (211 aa)
BTRCUncharacterized protein. (629 aa)
SEPTIN4-2Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (515 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (581 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (813 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (872 aa)
SKP1-2Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
RPS2Ribosomal protein S2. (293 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
DCUN1D1DCN1-like protein. (273 aa)
AIMP2Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (533 aa)
ENSMMUP00000058534UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
SKP2S-phase kinase-associated protein 2 isoform 1. (424 aa)
LOC702827Uncharacterized protein. (117 aa)
DDX3YATP-dependent RNA helicase DDX3Y; Belongs to the DEAD box helicase family. (659 aa)
RASSF1Ras association domain family member 1. (345 aa)
ENSMMUP00000061414S5 DRBM domain-containing protein. (137 aa)
SFXN2Uncharacterized protein. (383 aa)
XIAPX-linked inhibitor of apoptosis. (535 aa)
BIRC7Baculoviral IAP repeat containing 7. (410 aa)
SPSB4SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
SMAD7Mothers against decapentaplegic homolog. (462 aa)
ENSMMUP00000064139S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (150 aa)
EGK_08539Uncharacterized protein. (283 aa)
MASTLMicrotubule associated serine/threonine kinase like. (885 aa)
ENSMMUP00000067414S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (184 aa)
ENSMMUP00000067677Nucleoplasmin domain-containing protein. (183 aa)
CDK5RAP3CDK5 regulatory subunit-associated protein 3. (506 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
NDFIP2Nedd4 family interacting protein 2. (359 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (704 aa)
CBLBCbl proto-oncogene B. (982 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
TSPYL5Testis-specific Y-encoded-like protein 5; Belongs to the nucleosome assembly protein (NAP) family. (417 aa)
ENSMMUP00000072883Nucleoplasmin domain-containing protein. (250 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
FBXW9F-box and WD repeat domain containing 9. (502 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (618 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
DNAJB2J domain-containing protein. (332 aa)
NDFIP1Uncharacterized protein. (228 aa)
ARRDC4Arrestin domain containing 4. (470 aa)
INAVAInnate immunity activator. (703 aa)
ENSMMUP00000081054Uncharacterized protein. (321 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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