STRINGSTRING
RNF180 RNF180 AUP1 AUP1 TOLLIP TOLLIP RNF217 RNF217 MARCHF6 MARCHF6 SIAH1 SIAH1 UBE2V2 UBE2V2 SIAH2 SIAH2 PPARA PPARA TRAF6 TRAF6 PRKN PRKN ARIH1 ARIH1 RNF19B RNF19B FOXL2 FOXL2 ANKIB1 ANKIB1 ZMYM2 ZMYM2 MARCHF7 MARCHF7 RNF14 RNF14 RNF144B RNF144B ARIH2 ARIH2 RNF19A RNF19A ENSMMUP00000062234 ENSMMUP00000062234 ENSMMUP00000058534 ENSMMUP00000058534 DCUN1D1 DCUN1D1 SIAH3 SIAH3 ATPAF1 ATPAF1 DCUN1D4 DCUN1D4 RNF144A RNF144A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RNF180Ring finger protein 180. (592 aa)
AUP1AUP1 lipid droplet regulating VLDL assembly factor. (410 aa)
TOLLIPToll interacting protein. (276 aa)
RNF217RBR-type E3 ubiquitin transferase. (544 aa)
MARCHF6Membrane associated ring-CH-type finger 6. (952 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
TRAF6TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
ARIH1RBR-type E3 ubiquitin transferase. (557 aa)
RNF19BRBR-type E3 ubiquitin transferase. (732 aa)
FOXL2Forkhead box L2. (376 aa)
ANKIB1RBR-type E3 ubiquitin transferase. (1089 aa)
ZMYM2Uncharacterized protein. (1377 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (704 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
RNF144BRBR-type E3 ubiquitin transferase. (303 aa)
ARIH2RBR-type E3 ubiquitin transferase. (470 aa)
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)
ENSMMUP00000062234RBR-type E3 ubiquitin transferase. (228 aa)
ENSMMUP00000058534UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
DCUN1D1DCN1-like protein. (273 aa)
SIAH3E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (269 aa)
ATPAF1ATP synthase mitochondrial F1 complex assembly factor 1. (350 aa)
DCUN1D4DCN1-like protein. (398 aa)
RNF144ARBR-type E3 ubiquitin transferase. (292 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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