STRINGSTRING
FHL2 FHL2 SCN8A SCN8A PDLIM1 PDLIM1 FLNB FLNB BAG3 BAG3 RYR2 RYR2 NRAP NRAP CAPN3 CAPN3 FRG1 FRG1 RYR1 RYR1 PDLIM7 PDLIM7 MYO18B MYO18B ANK3 ANK3 CHORDC1 CHORDC1 FLNC FLNC ANKRD1 ANKRD1 C3H7orf57 C3H7orf57 PDE4B PDE4B ANKRD23 ANKRD23 SMTNL2 SMTNL2 PGM5 PGM5 SYNPO2 SYNPO2 MYOZ2 MYOZ2 TTN TTN PDLIM4 PDLIM4 TRIM63 TRIM63 CAB39 CAB39 KY KY NEBL NEBL FBXL22 FBXL22 F7DJI7_MACMU F7DJI7_MACMU DMD DMD CACNA1C CACNA1C JUP JUP XIRP2 XIRP2 IGFN1 IGFN1 FLNA FLNA MYL3 MYL3 BMP10 BMP10 SLC8A1 SLC8A1 PPP3CB PPP3CB SCN5A SCN5A JPH2 JPH2 HOMER1 HOMER1 SLC4A1 SLC4A1 CACNA1S CACNA1S CSRP2 CSRP2 GLRX3 GLRX3 KRT19 KRT19 PAK1 PAK1 PPP1R12A PPP1R12A PPP1R12B PPP1R12B ANKRD2 ANKRD2 ITGB1BP2 ITGB1BP2 NDST1 NDST1 MYOZ3 MYOZ3 KLHL40 KLHL40 C10orf71 C10orf71 TRIM54 TRIM54 STK11 STK11 PDLIM5 PDLIM5 SRI SRI KCNA5 KCNA5 AKAP4 AKAP4 FBXO32 FBXO32 PLEC PLEC ALDOA ALDOA MYZAP MYZAP PALLD PALLD ANK2 ANK2 UNC45B UNC45B MYOZ1 MYOZ1 ACTN3 ACTN3 NEXN NEXN FERMT2 FERMT2 SMTNL1 SMTNL1 STUB1 STUB1 MYPN MYPN ACTN1 ACTN1 ACTN2 ACTN2 NOS1AP NOS1AP MYH7 MYH7 FHL3 FHL3 FRG1-2 FRG1-2 LOC100424620 LOC100424620 CACNA1D CACNA1D SCN1A SCN1A BIN1 BIN1 SLC2A1 SLC2A1 ADRA1A ADRA1A PARVA PARVA RYR3 RYR3 C10orf113 C10orf113 KCNN2 KCNN2 LDB3 LDB3 PDLIM3 PDLIM3 OBSL1 OBSL1 PPP3CA PPP3CA SMN1 SMN1 KAT2B KAT2B CTNNB1 CTNNB1 SORBS2 SORBS2 CASQ1 CASQ1 IGSF22 IGSF22 DST DST RTN2 RTN2 FBP2 FBP2 GGPS1 GGPS1 CSRP3 CSRP3 SYNC SYNC SYNE2 SYNE2 SH2B1 SH2B1 LOC708538 LOC708538 ENSMMUP00000068957 ENSMMUP00000068957 FHOD3 FHOD3 PPP2R5A PPP2R5A PARVB PARVB DNAJB7 DNAJB7 FKBP1B FKBP1B CFL2 CFL2 HSPB1 HSPB1 ASB2 ASB2 ENSMMUP00000076909 ENSMMUP00000076909 JPH1 JPH1 SPEGNB SPEGNB ATP2B4 ATP2B4 DNAJB6 DNAJB6 HRC HRC MYL12A MYL12A SYNPO2L SYNPO2L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FHL2Four and a half LIM domains 2. (396 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
PDLIM1PDZ and LIM domain 1. (330 aa)
FLNBFilamin B. (2633 aa)
BAG3Uncharacterized protein. (575 aa)
RYR2Ryanodine receptor 2. (4967 aa)
NRAPNebulin related anchoring protein. (1731 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (821 aa)
FRG1FSHD region gene 1. (258 aa)
RYR1Ryanodine receptor 1. (4928 aa)
PDLIM7PDZ and LIM domain 7. (508 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2565 aa)
ANK3Ankyrin 3. (4375 aa)
CHORDC1Uncharacterized protein. (334 aa)
FLNCFilamin C. (2725 aa)
ANKRD1Ankyrin repeat domain 1. (318 aa)
C3H7orf57Chromosome 3 C7orf57 homolog. (323 aa)
PDE4BPhosphodiesterase. (736 aa)
ANKRD23Ankyrin repeat domain 23. (306 aa)
SMTNL2Smoothelin like 2. (461 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (530 aa)
SYNPO2Synaptopodin 2. (1261 aa)
MYOZ2Myozenin 2. (277 aa)
TTNTitin. (32000 aa)
PDLIM4PDZ and LIM domain protein 4 isoform 1. (330 aa)
TRIM63E3 ubiquitin-protein ligase TRIM63. (353 aa)
CAB39Calcium-binding protein 39. (341 aa)
KYKyphoscoliosis peptidase. (720 aa)
NEBLNebulette. (1028 aa)
FBXL22F-box and leucine rich repeat protein 22. (226 aa)
F7DJI7_MACMUUncharacterized protein. (445 aa)
DMDUncharacterized protein. (3685 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
JUPUncharacterized protein. (744 aa)
XIRP2Xin actin binding repeat containing 2. (3550 aa)
IGFN1Uncharacterized protein. (1282 aa)
FLNAFilamin-A isoform 2. (2647 aa)
MYL3Myosin light chain 3. (254 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
SLC8A1J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
HOMER1Homer scaffold protein 1. (374 aa)
SLC4A1Anion exchange protein. (914 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
CSRP2Cysteine and glycine-rich protein 2. (193 aa)
GLRX3Glutaredoxin 3. (335 aa)
KRT19Keratin, type I cytoskeletal 19; Belongs to the intermediate filament family. (400 aa)
PAK1Non-specific serine/threonine protein kinase. (575 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1090 aa)
ANKRD2Ankyrin repeat domain 2. (532 aa)
ITGB1BP2Integrin subunit beta 1 binding protein 2. (348 aa)
NDST1Uncharacterized protein. (1141 aa)
MYOZ3Uncharacterized protein. (251 aa)
KLHL40Kelch like family member 40. (621 aa)
C10orf71Chromosome 10 open reading frame 71. (1435 aa)
TRIM54Tripartite motif containing 54. (402 aa)
STK11Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (433 aa)
PDLIM5PDZ and LIM domain 5. (686 aa)
SRISorcin isoform a. (198 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
AKAP4A-kinase anchoring protein 4. (845 aa)
FBXO32F-box only protein 32 isoform 1. (355 aa)
PLECPlectin. (4862 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (418 aa)
MYZAPGRINL1A complex locus 1. (850 aa)
PALLDPalladin, cytoskeletal associated protein. (1400 aa)
ANK2Ankyrin 2. (4045 aa)
UNC45BUnc-45 myosin chaperone B. (929 aa)
MYOZ1Myozenin 1. (299 aa)
ACTN3Uncharacterized protein. (942 aa)
NEXNNexilin F-actin binding protein. (675 aa)
FERMT2PH domain-containing protein. (698 aa)
SMTNL1Smoothelin like 1. (512 aa)
STUB1STIP1 homology and U-box containing protein 1. (539 aa)
MYPNMyopalladin. (1346 aa)
ACTN1Actinin alpha 1. (914 aa)
ACTN2Actinin alpha 2. (894 aa)
NOS1APPID domain-containing protein. (695 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
FHL3Four and a half LIM domains protein 3. (280 aa)
FRG1-2Uncharacterized protein. (223 aa)
LOC100424620SMN domain-containing protein. (87 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2008 aa)
BIN1Bridging integrator 1. (668 aa)
SLC2A1MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (669 aa)
ADRA1AAdrenoceptor alpha 1A. (445 aa)
PARVAParvin alpha. (372 aa)
RYR3Ryanodine receptor 3. (4870 aa)
C10orf113Chromosome 10 open reading frame 113. (155 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (858 aa)
LDB3LIM domain binding 3. (732 aa)
PDLIM3PDZ and LIM domain 3. (404 aa)
OBSL1Obscurin like 1. (1896 aa)
PPP3CASerine/threonine-protein phosphatase. (547 aa)
SMN1Tudor domain-containing protein. (297 aa)
KAT2BLysine acetyltransferase 2B. (866 aa)
CTNNB1Catenin beta-1. (781 aa)
SORBS2Sorbin and SH3 domain containing 2. (1246 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (398 aa)
IGSF22Immunoglobulin superfamily member 22. (1326 aa)
DSTDystonin. (7760 aa)
RTN2Reticulon. (581 aa)
FBP2FBPase domain-containing protein; Belongs to the FBPase class 1 family. (345 aa)
GGPS1Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (300 aa)
CSRP3Cysteine and glycine rich protein 3. (253 aa)
SYNCSyncoilin, intermediate filament protein; Belongs to the intermediate filament family. (539 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6909 aa)
SH2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1087 aa)
LOC708538Tudor domain-containing protein. (275 aa)
ENSMMUP00000068957Uncharacterized protein. (164 aa)
FHOD3Uncharacterized protein. (1655 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
PARVBParvin beta. (406 aa)
DNAJB7DnaJ heat shock protein family (Hsp40) member B7. (309 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (790 aa)
ENSMMUP00000076909Uncharacterized protein. (102 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
SPEGNBSPEG neighbor. (238 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
DNAJB6DnaJ heat shock protein family (Hsp40) member B6. (326 aa)
HRCHistidine rich calcium binding protein. (799 aa)
MYL12AUncharacterized protein. (232 aa)
SYNPO2LUncharacterized protein. (979 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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