30 items (Macaca mulatta) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	SRD5A2	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
	HSD3B7	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7. (440 aa)
	HSD17B8	Estradiol 17-beta-dehydrogenase 8. (261 aa)
	LOC713738	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
	RDH8	Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
	HSD3B1	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; Belongs to the 3-beta-HSD family. (373 aa)
	HSD17B11	Estradiol 17-beta-dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
	DHRS9	Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (378 aa)
	HSD17B3	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa)
	HSD17B10	3-hydroxyacyl-CoA dehydrogenase type-2 isoform 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
	HSD17B12	Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
	HSD11B2	Hydroxysteroid 11-beta dehydrogenase 2. (405 aa)
	DHRS1	Dehydrogenase/reductase SDR family member 1. (313 aa)
	SDR42E2	Short chain dehydrogenase/reductase family 42E, member 2. (422 aa)
	HSD11B1	Uncharacterized protein. (292 aa)
	HSD3B2	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; A bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo- Delta(4)-steroids, an essential step in steroid hormone biosynthesis. Specifically catalyzes the conversion of pregnenolone to progesterone, 17alpha-hydroxypregnenolone to 17alpha-hydroxyprogesterone, dehydroepiandrosterone (DHEA) to 4-androstenedione and androstenediol to testosterone. Additionally, catalyzes the interconversion between 3beta-hydroxy and 3-oxo-5alpha-androstane steroids controllin [...] (422 aa)
	RDH16	Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
	SDR42E1	Short-chain dehydrogenase/reductase family 42E member 1; Belongs to the 3-beta-HSD family. (393 aa)
	AKR1C2	Aldo_ket_red domain-containing protein. (323 aa)
	LOC722496	Aldo_ket_red domain-containing protein. (322 aa)
	HSD17B6	17-beta-hydroxysteroid dehydrogenase type 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
	NSDHL	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (373 aa)
	RDH5	Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
	HSD17B7	Hydroxysteroid 17-beta dehydrogenase 7. (341 aa)
	FAM170A	Hydroxysteroid 17-beta dehydrogenase 4. (910 aa)
	AKR1C1	Aldo_ket_red domain-containing protein. (323 aa)
	HSD17B2	Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa)
	HSD17B14	Hydroxysteroid 17-beta dehydrogenase 14. (299 aa)
	AKR1C8P	Aldo-keto reductase family 1 member C8, pseudogene. (332 aa)
	CBR1	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (448 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKR1C1	AKR1C2	ENSMMUP00000047543	ENSMMUP00000071481	Aldo_ket_red domain-containing protein.	Aldo_ket_red domain-containing protein.	0.642
AKR1C1	CBR1	ENSMMUP00000047543	ENSMMUP00000062514	Aldo_ket_red domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.600
AKR1C1	DHRS1	ENSMMUP00000047543	ENSMMUP00000013140	Aldo_ket_red domain-containing protein.	Dehydrogenase/reductase SDR family member 1.	0.603
AKR1C1	DHRS9	ENSMMUP00000047543	ENSMMUP00000038206	Aldo_ket_red domain-containing protein.	Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.734
AKR1C1	HSD11B1	ENSMMUP00000047543	ENSMMUP00000080914	Aldo_ket_red domain-containing protein.	Uncharacterized protein.	0.919
AKR1C1	HSD17B12	ENSMMUP00000047543	ENSMMUP00000041952	Aldo_ket_red domain-containing protein.	Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.672
AKR1C1	HSD17B2	ENSMMUP00000047543	ENSMMUP00000049942	Aldo_ket_red domain-containing protein.	Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.454
AKR1C1	HSD17B3	ENSMMUP00000047543	ENSMMUP00000038724	Aldo_ket_red domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.616
AKR1C1	HSD17B6	ENSMMUP00000047543	ENSMMUP00000069408	Aldo_ket_red domain-containing protein.	17-beta-hydroxysteroid dehydrogenase type 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.401
AKR1C1	HSD3B1	ENSMMUP00000047543	ENSMMUP00000015345	Aldo_ket_red domain-containing protein.	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; Belongs to the 3-beta-HSD family.	0.533
AKR1C1	HSD3B2	ENSMMUP00000047543	ENSMMUP00000077828	Aldo_ket_red domain-containing protein.	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; A bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo- Delta(4)-steroids, an essential step in steroid hormone biosynthesis. Specifically catalyzes the conversion of pregnenolone to progesterone, 17alpha-hydroxypregnenolone to 17alpha-hydroxyprogesterone, dehydroepiandrosterone (DHEA) to 4-androstenedione and androstenediol to testosterone. Additionally, catalyzes the interconversion between 3beta-hydroxy and 3-oxo-5alpha-androstane steroids controllin [...]	0.569
AKR1C1	NSDHL	ENSMMUP00000047543	ENSMMUP00000068619	Aldo_ket_red domain-containing protein.	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family.	0.401
AKR1C1	RDH16	ENSMMUP00000047543	ENSMMUP00000076800	Aldo_ket_red domain-containing protein.	Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.507
AKR1C1	SRD5A2	ENSMMUP00000047543	ENSMMUP00000065479	Aldo_ket_red domain-containing protein.	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.	0.928
AKR1C2	AKR1C1	ENSMMUP00000071481	ENSMMUP00000047543	Aldo_ket_red domain-containing protein.	Aldo_ket_red domain-containing protein.	0.642
AKR1C2	CBR1	ENSMMUP00000071481	ENSMMUP00000062514	Aldo_ket_red domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.543
AKR1C2	DHRS1	ENSMMUP00000071481	ENSMMUP00000013140	Aldo_ket_red domain-containing protein.	Dehydrogenase/reductase SDR family member 1.	0.544
AKR1C2	DHRS9	ENSMMUP00000071481	ENSMMUP00000038206	Aldo_ket_red domain-containing protein.	Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.615
AKR1C2	HSD11B1	ENSMMUP00000071481	ENSMMUP00000080914	Aldo_ket_red domain-containing protein.	Uncharacterized protein.	0.493
AKR1C2	HSD17B3	ENSMMUP00000071481	ENSMMUP00000038724	Aldo_ket_red domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.560