STRINGSTRING
SERPINB1 SERPINB1 PDXK PDXK CLEC3B CLEC3B SCG3 SCG3 LCN2 LCN2 LOC106995978 LOC106995978 ERP44 ERP44 KNG1 KNG1 PSMA5 PSMA5 TRAPPC1 TRAPPC1 FRK FRK CDA CDA CYFIP1 CYFIP1 PTX3 PTX3 XRCC6 XRCC6 S100A12 S100A12 PRKCD PRKCD GIP GIP DOCK2 DOCK2 ACTR10 ACTR10 ARG1 ARG1 GGH GGH S100A11-2 S100A11-2 GALNS GALNS PF4 PF4 CANT1 CANT1 MMP8 MMP8 RAB27A RAB27A PSMD11 PSMD11 PYCARD PYCARD PSMB7 PSMB7 ARSB ARSB DNASE1L1 DNASE1L1 CRACR2A CRACR2A GCG GCG RETN RETN VPS13A VPS13A ARSA ARSA BIN2 BIN2 QPCT QPCT COTL1 COTL1 CLU CLU DYNC1H1 DYNC1H1 SERPINE1 SERPINE1 FAM49B FAM49B SLPI SLPI C1H1orf35 C1H1orf35 DSN1 DSN1 PDGFB PDGFB FGR FGR PSMD7 PSMD7 LOC714514 LOC714514 DPP7 DPP7 FN1 FN1 TGFB2 TGFB2 HEXB HEXB SPARC SPARC EEF1E1 EEF1E1 SERPINI1 SERPINI1 CREG1 CREG1 GHRL GHRL PRTN3 PRTN3 IMPDH1 IMPDH1 ECM1 ECM1 ALAD ALAD SDCBP SDCBP GYG1 GYG1 PYGL PYGL COMMD9 COMMD9 VWF VWF FAM3C FAM3C PSMA2 PSMA2 PSMD14 PSMD14 STK11IP STK11IP ACLY ACLY PPBP PPBP FAF2 FAF2 GNS GNS OSCAR OSCAR DERA DERA S100A8 S100A8 SPTAN1 SPTAN1 GLA GLA F5 F5 SRGN SRGN DBNL DBNL ACTN2 ACTN2 NHLRC2 NHLRC2 PCSK1 PCSK1 GMFG GMFG DNAJC3 DNAJC3 ACTR1B ACTR1B PSMD6 PSMD6 CTSA CTSA NFKB1 NFKB1 AZU1 AZU1 GSDMD GSDMD GRN GRN TGFB1 TGFB1 LRG1 LRG1 APAF1 APAF1 ARHGAP9 ARHGAP9 LRRC7 LRRC7 S100P S100P ATG7 ATG7 NEU1 NEU1 PCYOX1L PCYOX1L AGL AGL PRDX4 PRDX4 FGG FGG FGA FGA FGB FGB VCL VCL AOC1 AOC1 PSMD3 PSMD3 VCP VCP BPI BPI PSMB1 PSMB1 CRISP3 CRISP3 KPNB1 KPNB1 DYNLT1 DYNLT1 PNP PNP HRG HRG PRG3 PRG3 DBH DBH EGK_20852 EGK_20852 VAT1 VAT1 VTI1B VTI1B CEP290 CEP290 AMPD3 AMPD3 VEGFD VEGFD PSMC3 PSMC3 CTSZ CTSZ ITIH4 ITIH4 LTF LTF SPACA7 SPACA7 TCN1 TCN1 HPSE HPSE JUP JUP GSN GSN VEGFB VEGFB FERMT3 FERMT3 SERPING1 SERPING1 MAPK1 MAPK1 A1BG A1BG GMFB GMFB SPP2 SPP2 TGFB3 TGFB3 EPX EPX PSMD13 PSMD13 CRISPLD2 CRISPLD2 FOLR2 FOLR2 OSTF1 OSTF1 F8 F8 PTPN6 PTPN6 CTSH CTSH EGF EGF CAB39 CAB39 CFD CFD ELANE ELANE GTPBP2 GTPBP2 PGLYRP1 PGLYRP1 CHIT1 CHIT1 C3 C3 CTSW CTSW ORM1 ORM1 GRP GRP S100A9 S100A9 PENK PENK HUWE1 HUWE1 THBS1 THBS1 IMPDH2 IMPDH2 TIMP2 TIMP2 PDGFA PDGFA TOR4A TOR4A S100A11 S100A11 CTSG CTSG VEGFC VEGFC TOLLIP TOLLIP UNC13D UNC13D OLFM4 OLFM4 HK3 HK3 SERPINF2 SERPINF2 MPO MPO XRCC5 XRCC5 NAPRT NAPRT PADI2 PADI2 F13A1 F13A1 ACAA1 ACAA1 LOC698764 LOC698764 F6YRS3_MACMU F6YRS3_MACMU HEBP2 HEBP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SERPINB1SERPIN domain-containing protein; Belongs to the serpin family. (391 aa)
PDXKPyridoxal kinase. (312 aa)
CLEC3BTetranectin. (202 aa)
SCG3Uncharacterized protein. (602 aa)
LCN2Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (237 aa)
LOC106995978Epidermal-type fatty acid-binding protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
ERP44Endoplasmic reticulum resident protein 44. (406 aa)
KNG1Kininogen 1. (644 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
TRAPPC1Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (145 aa)
FRKTyrosine-protein kinase. (529 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (182 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
PTX3Pentraxin 3. (381 aa)
XRCC6X-ray repair cross-complementing protein 6. (609 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (90 aa)
PRKCDProtein kinase C. (729 aa)
GIPGastric inhibitory polypeptide. (153 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1867 aa)
ACTR10Actin-related protein 10; Belongs to the actin family. (417 aa)
ARG1Arginase. (322 aa)
GGHFolate gamma-glutamyl hydrolase. (318 aa)
S100A11-2S100 calcium binding protein A11. (105 aa)
GALNSGalactosamine (N-acetyl)-6-sulfatase. (599 aa)
PF4C-X-C motif chemokine. (101 aa)
CANT1Calcium activated nucleotidase 1. (450 aa)
MMP8Matrix metallopeptidase 8. (467 aa)
RAB27AUncharacterized protein. (321 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (454 aa)
PYCARDApoptosis-associated speck-like protein containing a CARD isoform a. (195 aa)
PSMB7Proteasome subunit beta. (277 aa)
ARSBArylsulfatase B. (534 aa)
DNASE1L1Deoxyribonuclease; Belongs to the DNase I family. (302 aa)
CRACR2ACalcium release activated channel regulator 2A. (731 aa)
GCGGlucagon. (263 aa)
RETNUncharacterized protein. (248 aa)
VPS13AVacuolar protein sorting 13 homolog A. (3421 aa)
ARSAArylsulfatase A. (507 aa)
BIN2Bridging integrator 2. (592 aa)
QPCTGlutaminyl-peptide cyclotransferase. (349 aa)
COTL1Coactosin-like protein. (142 aa)
CLUClusterin; Belongs to the clusterin family. (489 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4685 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (407 aa)
FAM49BFamily with sequence similarity 49 member B. (324 aa)
SLPIUncharacterized protein. (132 aa)
C1H1orf35Uncharacterized protein. (323 aa)
DSN1Kinetochore-associated protein DSN1 homolog isoform 1. (354 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (265 aa)
FGRTyrosine-protein kinase. (529 aa)
PSMD7MPN domain-containing protein. (323 aa)
LOC714514Uncharacterized protein. (1786 aa)
DPP7Dipeptidyl peptidase 7. (569 aa)
FN1Fibronectin isoform 1 preproprotein. (2477 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
HEXBBeta-hexosaminidase. (557 aa)
SPARCKazal-like domain-containing protein. (343 aa)
EEF1E1Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (431 aa)
SERPINI1Serpin family I member 1; Belongs to the serpin family. (410 aa)
CREG1Uncharacterized protein; Belongs to the CREG family. (220 aa)
GHRLGhrelin and obestatin prepropeptide. (222 aa)
PRTN3Proteinase 3; Belongs to the peptidase S1 family. (265 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (599 aa)
ECM1Extracellular matrix protein 1 isoform 1. (540 aa)
ALADDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (387 aa)
SDCBPSyndecan binding protein. (324 aa)
GYG1Glycogenin-1 isoform 1. (350 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa)
COMMD9Uncharacterized protein. (237 aa)
VWFUncharacterized protein. (2888 aa)
FAM3CFamily with sequence similarity 3, member C. (227 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
STK11IPSerine/threonine kinase 11 interacting protein. (1115 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1155 aa)
PPBPC-X-C motif chemokine. (128 aa)
FAF2Fas associated factor family member 2. (445 aa)
GNSN-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (552 aa)
OSCAROsteoclast associated Ig-like receptor. (252 aa)
DERAPutative deoxyribose-phosphate aldolase. (318 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
SPTAN1Spectrin alpha chain, brain isoform 2. (2472 aa)
GLAAlpha-galactosidase. (429 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2181 aa)
SRGNSerglycin. (153 aa)
DBNLUncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (536 aa)
ACTN2Actinin alpha 2. (894 aa)
NHLRC2NHL repeat containing 2. (731 aa)
PCSK1Neuroendocrine convertase 1 isoform 1 preproprotein; Belongs to the peptidase S8 family. (749 aa)
GMFGGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (150 aa)
DNAJC3Interferon-induced, double-stranded RNA-activated protein kinase inhibitor. (504 aa)
ACTR1BActin related protein 1B; Belongs to the actin family. (343 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (494 aa)
NFKB1Uncharacterized protein. (977 aa)
AZU1Azurocidin 1. (250 aa)
GSDMDGasdermin D. (529 aa)
GRNGranulin precursor. (593 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (383 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1206 aa)
ARHGAP9Rho GTPase activating protein 9. (824 aa)
LRRC7Leucine rich repeat containing 7. (1537 aa)
S100PS100 calcium binding protein P. (95 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (770 aa)
NEU1Neuraminidase 1. (416 aa)
PCYOX1LPrenylcysteine oxidase 1 like. (494 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1532 aa)
PRDX4Peroxiredoxin 4. (281 aa)
FGGFibrinogen gamma chain. (437 aa)
FGAFibrinogen alpha chain. (928 aa)
FGBFibrinogen beta chain. (491 aa)
VCLVinculin. (1134 aa)
AOC1Amine oxidase. (755 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
VCPUncharacterized protein; Belongs to the AAA ATPase family. (823 aa)
BPIBactericidal permeability increasing protein. (582 aa)
PSMB1Proteasome subunit beta. (241 aa)
CRISP3Cysteine rich secretory protein 3; Belongs to the CRISP family. (295 aa)
KPNB1Karyopherin subunit beta 1. (856 aa)
DYNLT1Dynein light chain Tctex-type 1. (113 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
HRGHistidine rich glycoprotein. (525 aa)
PRG3Proteoglycan 3, pro eosinophil major basic protein 2. (225 aa)
DBHDopamine beta-hydroxylase. (620 aa)
EGK_20852Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
VAT1Vesicle amine transport protein 1. (401 aa)
VTI1Bt-SNARE coiled-coil homology domain-containing protein. (392 aa)
CEP290Centrosomal protein 290. (2480 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (776 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (439 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain 4. (977 aa)
LTFLactotransferrin; Belongs to the transferrin family. (747 aa)
SPACA7Sperm acrosome associated 7. (195 aa)
TCN1Transcobalamin-1. (434 aa)
HPSEHeparanase. (545 aa)
JUPUncharacterized protein. (744 aa)
GSNGelsolin. (809 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
FERMT3Fermitin family member 3. (744 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (627 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
A1BGAlpha-1-B glycoprotein. (549 aa)
GMFBGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (154 aa)
SPP2Secreted phosphoprotein 2. (242 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
EPXEosinophil peroxidase. (715 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (378 aa)
CRISPLD2Cysteine rich secretory protein LCCL domain containing 2. (497 aa)
FOLR2Folate_rec domain-containing protein. (272 aa)
OSTF1Osteoclast-stimulating factor 1. (214 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2351 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (626 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1213 aa)
CAB39Calcium-binding protein 39. (341 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (260 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa)
GTPBP2GTP binding protein 2. (561 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa)
CHIT1Chitinase 1; Belongs to the glycosyl hydrolase 18 family. (481 aa)
C3Uncharacterized protein. (1663 aa)
CTSWCathepsin W; Belongs to the peptidase C1 family. (375 aa)
ORM1Alpha-1-acid glycoprotein; Functions as transport protein in the blood stream. Belongs to the calycin superfamily. Lipocalin family. (205 aa)
GRPGastrin releasing peptide. (161 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
PENKProenkephalin. (300 aa)
HUWE1E3 ubiquitin-protein ligase HUWE1. (4374 aa)
THBS1Thrombospondin 1. (1170 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (538 aa)
TIMP2NTR domain-containing protein. (499 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (249 aa)
TOR4AAAA domain-containing protein. (423 aa)
S100A11Protein S100; Belongs to the S-100 family. (105 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa)
TOLLIPToll interacting protein. (276 aa)
UNC13DUnc-13 homolog D. (1090 aa)
OLFM4Olfactomedin 4. (512 aa)
HK3Hexokinase 3. (923 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (594 aa)
MPOMyeloperoxidase. (745 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
NAPRTNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (538 aa)
PADI2Peptidyl arginine deiminase 2. (687 aa)
F13A1Coagulation factor XIII A chain. (749 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (454 aa)
LOC698764Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (513 aa)
F6YRS3_MACMUKu domain-containing protein. (326 aa)
HEBP2Uncharacterized protein. (205 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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