STRINGSTRING
GRID1 GRID1 AVPR1A AVPR1A PTCHD1 PTCHD1 DRD4 DRD4 SLC6A4 SLC6A4 TH TH SHANK3 SHANK3 RPTOR RPTOR GRP GRP KCNQ1 KCNQ1 PTEN PTEN EXT1 EXT1 SHANK1 SHANK1 OXT OXT BBS4 BBS4 NRXN3 NRXN3 GAD1 GAD1 CNTNAP2 CNTNAP2 NPAS4 NPAS4 KALRN KALRN NRXN2 NRXN2 GRPR GRPR CHD8 CHD8 TREM2 TREM2 FAM155A FAM155A MKKS MKKS NLGN3 NLGN3 DVL1 DVL1 NRXN1 NRXN1 TBX1 TBX1 CIC CIC MECP2 MECP2 UCN UCN CLN8 CLN8 SEPTIN5 SEPTIN5 SHANK2 SHANK2 ATXN1 ATXN1 CX3CR1 CX3CR1 DLG4 DLG4 EIF4EBP2 EIF4EBP2 NR2E1 NR2E1 EN1 EN1 PTCHD4 PTCHD4 VPS13A VPS13A AVP AVP ATXN1L ATXN1L NLGN2 NLGN2 PCM1 PCM1 BRINP1 BRINP1 MAPK8IP2 MAPK8IP2 CHRNB2 CHRNB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRID1Glutamate receptor delta-1 subunit. (1009 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa)
PTCHD1Patched domain containing 1. (888 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (418 aa)
SLC6A4Sodium-dependent serotonin transporter; Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily. (630 aa)
THTyrosine hydroxylase. (501 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1730 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
GRPGastrin releasing peptide. (161 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
PTENUncharacterized protein. (589 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2163 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
BBS4Bardet-Biedl syndrome 4 protein. (519 aa)
NRXN3Neurexin 3. (1571 aa)
GAD1Glutamate decarboxylase 1 isoform GAD67. (594 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
NPAS4Neuronal PAS domain protein 4. (802 aa)
KALRNUncharacterized protein. (2987 aa)
NRXN2Neurexin 2. (1713 aa)
GRPRG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (384 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2581 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (291 aa)
FAM155AFamily with sequence similarity 155 member A. (457 aa)
MKKSMcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (570 aa)
NLGN3Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity). (848 aa)
DVL1Dishevelled segment polarity protein 1. (695 aa)
NRXN1Uncharacterized protein. (1547 aa)
TBX1T-box transcription factor 1. (496 aa)
CICCapicua transcriptional repressor. (2517 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
UCNUrocortin. (124 aa)
CLN8Protein CLN8. (286 aa)
SEPTIN5Septin 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (442 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1846 aa)
ATXN1Ataxin 1. (817 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
DLG4Uncharacterized protein; Belongs to the MAGUK family. (972 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E-binding protein 2. (120 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (390 aa)
EN1Homeobox protein engrailed-like. (398 aa)
PTCHD4Patched domain containing 4. (904 aa)
VPS13AVacuolar protein sorting 13 homolog A. (3421 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
ATXN1LAXH domain-containing protein. (691 aa)
NLGN2COesterase domain-containing protein. (836 aa)
PCM1Pericentriolar material 1. (2190 aa)
BRINP1Deleted in bladder cancer protein 1. (761 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (936 aa)
CHRNB2Neuronal acetylcholine receptor subunit beta-2. (502 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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