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ARID5B ARID5B SIDT2 SIDT2 THRA THRA HNF1B HNF1B GSX1 GSX1 ASCL1 ASCL1 NOG NOG TSPO TSPO GDF11 GDF11 HNF4A HNF4A NF1 NF1 GIPR GIPR GATA3 GATA3 GCM2 GCM2 NEUROD1 NEUROD1 CDK6 CDK6 DUOX2 DUOX2 NEUROG3 NEUROG3 EIF2AK3 EIF2AK3 WT1 WT1 FOXA2 FOXA2 PBX1 PBX1 F7B371_MACMU F7B371_MACMU PDPK1 PDPK1 PAX8 PAX8 CDH1 CDH1 BMP5 BMP5 SMO SMO MAPK1 MAPK1 NR0B1 NR0B1 CYP1B1 CYP1B1 NR5A1 NR5A1 DRD2 DRD2 SOX4 SOX4 CDH2 CDH2 PAX4 PAX4 FGF8 FGF8 APOA1 APOA1 RFX6 RFX6 SALL1 SALL1 SMAD4 SMAD4 ALDH1A2 ALDH1A2 DLL1 DLL1 NKX6-1 NKX6-1 CRH CRH BMP6 BMP6 GLI1 GLI1 DKK3 DKK3 IL6R IL6R ONECUT2 ONECUT2 SRF SRF EDNRA EDNRA MEN1 MEN1 CREB1 CREB1 GHRH GHRH GATA2 GATA2 RFX3 RFX3 FOXE1 FOXE1 LHX3 LHX3 SMAD3 SMAD3 STRA6 STRA6 CITED4 CITED4 GHRHR GHRHR PCSK1 PCSK1 BRAF BRAF TG TG OTP OTP ENSMMUP00000049472 ENSMMUP00000049472 CITED2 CITED2 TGFBR1 TGFBR1 TBX1 TBX1 MAPK3 MAPK3 FGF10 FGF10 ARMC5 ARMC5 HESX1 HESX1 CRHR1 CRHR1 GLI2 GLI2 MDK MDK MNX1 MNX1 EDN1 EDN1 WNT11 WNT11 ISL1 ISL1 LOC114675515 LOC114675515 SLC6A3 SLC6A3 SHH SHH BMP2 BMP2 PAX1 PAX1 NKX6-2 NKX6-2 NKX2-2 NKX2-2 NKX2-1 NKX2-1 PITX2 PITX2 BAK1 BAK1 WNT4 WNT4 PROP1 PROP1 HOXA5 HOXA5 NKX2-5 NKX2-5 HOXA3 HOXA3 PITX1 PITX1 HOXD3 HOXD3 GATA6 GATA6 WNT5A WNT5A TBX19 TBX19 GIP GIP SIX3 SIX3 SIX1 SIX1 BMP4 BMP4 PDX1 PDX1 PAX6 PAX6 INHBB INHBB BMPR1A BMPR1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARID5BAT-rich interaction domain 5B. (1205 aa)
SIDT2SID1 transmembrane family member 2. (857 aa)
THRAThyroid hormone receptor alpha. (486 aa)
HNF1BHepatocyte nuclear factor 1-beta. (557 aa)
GSX1GS homeobox 1. (264 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (238 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TSPOTranslocator protein isoform PBR. (169 aa)
GDF11Growth differentiation factor 11. (408 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
NF1Neurofibromin 1. (2867 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
GATA3GATA binding protein 3. (444 aa)
GCM2Glial cells missing transcription factor 2. (506 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (335 aa)
DUOX2Dual oxidase 2. (1546 aa)
NEUROG3Neurogenin 3. (215 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
WT1WT1 transcription factor. (517 aa)
FOXA2Forkhead box A2. (457 aa)
PBX1Pre-B-cell leukemia transcription factor 1 isoform 1. (430 aa)
F7B371_MACMUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (313 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (557 aa)
PAX8Paired box 8. (456 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. (470 aa)
CYP1B1Uncharacterized protein; Belongs to the cytochrome P450 family. (542 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (500 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
SOX4Transcription factor SOX. (467 aa)
CDH2Cadherin-2 preproprotein; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
PAX4Paired box 4. (343 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (267 aa)
RFX6Regulatory factor X6. (928 aa)
SALL1Spalt like transcription factor 1. (1324 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ALDH1A2Retinal dehydrogenase 2 isoform 1; Belongs to the aldehyde dehydrogenase family. (518 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
NKX6-1NK6 homeobox 1. (366 aa)
CRHCorticotropin releasing hormone. (196 aa)
BMP6Bone morphogenetic protein 6. (511 aa)
GLI1Zinc finger protein GLI1 isoform 1. (1106 aa)
DKK3Dickkopf-related protein 3. (350 aa)
IL6RInterleukin 6 receptor. (536 aa)
ONECUT2One cut domain family member. (505 aa)
SRFSerum response factor. (508 aa)
EDNRAUncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (427 aa)
MEN1Menin isoform 2. (610 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
GHRHGrowth hormone releasing hormone. (108 aa)
GATA2GATA binding protein 2. (480 aa)
RFX3Regulatory factor X3. (760 aa)
FOXE1Forkhead box E1. (372 aa)
LHX3LIM homeobox 3. (402 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
STRA6Stimulated by retinoic acid 6. (707 aa)
CITED4Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (232 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (565 aa)
PCSK1Neuroendocrine convertase 1 isoform 1 preproprotein; Belongs to the peptidase S8 family. (749 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
TGThyroglobulin. (2643 aa)
OTPOrthopedia homeobox. (325 aa)
ENSMMUP00000049472Uncharacterized protein. (370 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
TBX1T-box transcription factor 1. (496 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ARMC5Armadillo repeat containing 5. (1030 aa)
HESX1HESX homeobox 1. (185 aa)
CRHR1Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...] (444 aa)
GLI2GLI family zinc finger 2. (1569 aa)
MDKMidkine. (143 aa)
MNX1Motor neuron and pancreas homeobox 1. (404 aa)
EDN1Preproendothelin-1. (211 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
ISL1ISL LIM homeobox 1. (413 aa)
LOC114675515Uncharacterized protein. (152 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (631 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
PAX1Paired box 1. (535 aa)
NKX6-2Homeobox protein Nkx-6.2. (277 aa)
NKX2-2Homeobox domain-containing protein. (451 aa)
NKX2-1NK2 homeobox 1. (448 aa)
PITX2Homeobox protein. (354 aa)
BAK1Uncharacterized protein. (261 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
PROP1PROP paired-like homeobox 1. (234 aa)
HOXA5Homeobox A5. (381 aa)
NKX2-5NK2 homeobox 5. (324 aa)
HOXA3Homeobox A3. (443 aa)
PITX1Homeobox protein. (348 aa)
HOXD3Homeobox D3. (432 aa)
GATA6Transcription factor GATA-6. (595 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (462 aa)
TBX19T-box transcription factor 19. (448 aa)
GIPGastric inhibitory polypeptide. (153 aa)
SIX3SIX homeobox 3. (384 aa)
SIX1SIX homeobox 1. (284 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
PDX1Pancreatic and duodenal homeobox 1. (281 aa)
PAX6Uncharacterized protein. (598 aa)
INHBBInhibin subunit beta B. (407 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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