43 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTN	Uncharacterized protein. (172 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
	NLGN1	Neuroligin-1. (823 aa)
	ITGB7	Integrin beta; Belongs to the integrin beta chain family. (807 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1730 aa)
	MUSK	Muscle associated receptor tyrosine kinase. (869 aa)
	DNAJA3	DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
	SLITRK3	SLIT and NTRK like family member 3. (979 aa)
	FLNA	Filamin-A isoform 2. (2647 aa)
	GRIK5	Glutamate ionotropic receptor kainate type subunit 5. (1388 aa)
	CDK5	Cyclin dependent kinase 5. (364 aa)
	LRRC7	Leucine rich repeat containing 7. (1537 aa)
	NRXN2	Neurexin 2. (1713 aa)
	ITGAL	Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1169 aa)
	GPHN	Gephyrin. (801 aa)
	GLRB	Glycine receptor subunit beta isoform A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
	WDR19	WD_REPEATS_REGION domain-containing protein. (1348 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (565 aa)
	DLG2	Discs large MAGUK scaffold protein 2. (975 aa)
	LRP4	Low-density lipoprotein receptor-related protein 4. (1905 aa)
	DLG1	Disks large homolog 1 isoform 2; Belongs to the MAGUK family. (926 aa)
	CHRDL1	Chordin-like protein 1 isoform 1. (458 aa)
	DLG3	Uncharacterized protein; Belongs to the MAGUK family. (867 aa)
	SYNGAP1	Synaptic Ras GTPase activating protein 1. (1303 aa)
	DVL1	Dishevelled segment polarity protein 1. (695 aa)
	NRXN1	Uncharacterized protein. (1547 aa)
	MADCAM1	Ig-like domain-containing protein. (519 aa)
	SCRIB	Scribble planar cell polarity protein. (1451 aa)
	APOE	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
	AGRN	Agrin. (2067 aa)
	SSNA1	Sjoegren syndrome nuclear autoantigen 1. (119 aa)
	MAGI2	Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1452 aa)
	LRRC1	Leucine-rich repeat-containing protein 1. (524 aa)
	SAV1	Salvador family WW domain containing protein 1. (384 aa)
	COX16	PDZ domain-containing protein. (182 aa)
	RELN	Reelin. (3460 aa)
	DLG4	Uncharacterized protein; Belongs to the MAGUK family. (972 aa)
	LHFPL4	Uncharacterized protein. (247 aa)
	ITGB2	Integrin beta. (911 aa)
	NLGN2	COesterase domain-containing protein. (836 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (279 aa)
	SHISA7	Shisa family member 7. (659 aa)
	PIGR	Polymeric immunoglobulin receptor. (764 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRN	APOE	ENSMMUP00000048963	ENSMMUP00000048554	Agrin.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.574
AGRN	LRP4	ENSMMUP00000048963	ENSMMUP00000037130	Agrin.	Low-density lipoprotein receptor-related protein 4.	0.974
AGRN	MUSK	ENSMMUP00000048963	ENSMMUP00000009260	Agrin.	Muscle associated receptor tyrosine kinase.	0.930
AGRN	NRXN1	ENSMMUP00000048963	ENSMMUP00000046829	Agrin.	Uncharacterized protein.	0.423
AGRN	NRXN2	ENSMMUP00000048963	ENSMMUP00000029746	Agrin.	Neurexin 2.	0.502
APOE	AGRN	ENSMMUP00000048554	ENSMMUP00000048963	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Agrin.	0.574
CDK5	DLG4	ENSMMUP00000026930	ENSMMUP00000068361	Cyclin dependent kinase 5.	Uncharacterized protein; Belongs to the MAGUK family.	0.937
DLG1	DLG2	ENSMMUP00000038226	ENSMMUP00000036808	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 2.	0.928
DLG1	DLG3	ENSMMUP00000038226	ENSMMUP00000040999	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	Uncharacterized protein; Belongs to the MAGUK family.	0.703
DLG1	DLG4	ENSMMUP00000038226	ENSMMUP00000068361	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	Uncharacterized protein; Belongs to the MAGUK family.	0.772
DLG1	LRRC7	ENSMMUP00000038226	ENSMMUP00000028859	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	Leucine rich repeat containing 7.	0.468
DLG1	NLGN1	ENSMMUP00000038226	ENSMMUP00000006211	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	Neuroligin-1.	0.436
DLG1	NLGN2	ENSMMUP00000038226	ENSMMUP00000074682	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	COesterase domain-containing protein.	0.409
DLG1	NRXN1	ENSMMUP00000038226	ENSMMUP00000046829	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	Uncharacterized protein.	0.440
DLG1	NRXN2	ENSMMUP00000038226	ENSMMUP00000029746	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	Neurexin 2.	0.436
DLG1	SCRIB	ENSMMUP00000038226	ENSMMUP00000047144	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	Scribble planar cell polarity protein.	0.461
DLG1	SHANK3	ENSMMUP00000038226	ENSMMUP00000007390	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 3.	0.613
DLG2	DLG1	ENSMMUP00000036808	ENSMMUP00000038226	Discs large MAGUK scaffold protein 2.	Disks large homolog 1 isoform 2; Belongs to the MAGUK family.	0.928
DLG2	DLG3	ENSMMUP00000036808	ENSMMUP00000040999	Discs large MAGUK scaffold protein 2.	Uncharacterized protein; Belongs to the MAGUK family.	0.769
DLG2	DLG4	ENSMMUP00000036808	ENSMMUP00000068361	Discs large MAGUK scaffold protein 2.	Uncharacterized protein; Belongs to the MAGUK family.	0.828