STRINGSTRING
UNC13B UNC13B HCN3 HCN3 SLC1A1 SLC1A1 KCNA6 KCNA6 FLRT3 FLRT3 CYFIP1 CYFIP1 OPHN1 OPHN1 CABP4 CABP4 TANC1 TANC1 NTRK2 NTRK2 BTBD8 BTBD8 VTI1A VTI1A UCN3 UCN3 DLG4 DLG4 SLC8A3 SLC8A3 SYP SYP TPBG TPBG SLC6A3 SLC6A3 PRNP PRNP KCNA1 KCNA1 CALCA CALCA AVPR1B AVPR1B TPRG1L TPRG1L P2RX3 P2RX3 PRKCB PRKCB SNCA SNCA PTPRN PTPRN CASR CASR UCN UCN FMR1 FMR1 GIT1 GIT1 P2RX4 P2RX4 BAIAP2 BAIAP2 BIN1 BIN1 ITGA2 ITGA2 SLC8A2 SLC8A2 UNC13A UNC13A SRSF10 SRSF10 CPLX4 CPLX4 SLC18A2 SLC18A2 ATP1A3 ATP1A3 SLC4A10 SLC4A10 DIXDC1 DIXDC1 CAD CAD GPER1 GPER1 EPHA4 EPHA4 SLC18A3 SLC18A3 TSPOAP1 TSPOAP1 NMU NMU PCSK1 PCSK1 PTPN9 PTPN9 AAK1 AAK1 UNC13C UNC13C LOC114672301 LOC114672301 SEPTIN6 SEPTIN6 GRIN1 GRIN1 KCNC2 KCNC2 GHRH GHRH SLC1A2 SLC1A2 SYNJ1 SYNJ1 KCNC3 KCNC3 PRKCG PRKCG MICAL1 MICAL1 NTS NTS CRHBP CRHBP SLC18A1 SLC18A1 ELK1 ELK1 KCNA2 KCNA2 CDH8 CDH8 MACO1 MACO1 SLC17A8 SLC17A8 GRIK5 GRIK5 KCNK2 KCNK2 NTSR1 NTSR1 LRRK2 LRRK2 AP3D1 AP3D1 SLC8A1 SLC8A1 PRSS12 PRSS12 GAD1 GAD1 BSN BSN CPLX3 CPLX3 DMD DMD CRHR2 CRHR2 SLC9A6 SLC9A6 OXT OXT PDYN PDYN PRRT2 PRRT2 CALB2 CALB2 PACSIN1 PACSIN1 PNOC PNOC PENK PENK MME MME SLC4A8 SLC4A8 KCNC1 KCNC1 TULP1 TULP1 ROR1 ROR1 GCH1 GCH1 TH TH SLC32A1 SLC32A1 SCGN SCGN SCRG1 SCRG1 TNN TNN FLRT1 FLRT1 SNCB SNCB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UNC13BUnc-13 homolog B. (1971 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (777 aa)
SLC1A1Excitatory amino acid transporter 3. (524 aa)
KCNA6BTB domain-containing protein; Belongs to the potassium channel family. (530 aa)
FLRT3Fibronectin-like domain-containing leucine-rich transmembrane protein 3. (649 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
OPHN1Oligophrenin-1. (802 aa)
CABP4Calcium binding protein 4. (303 aa)
TANC1Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (2023 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
BTBD8BTB domain containing 8. (1964 aa)
VTI1At-SNARE coiled-coil homology domain-containing protein. (228 aa)
UCN3Urocortin 3. (210 aa)
DLG4Uncharacterized protein; Belongs to the MAGUK family. (972 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
SYPSynaptophysin. (401 aa)
TPBGUncharacterized protein. (420 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (631 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (253 aa)
KCNA1Voltage-gated potassium channel subunit Kv1.1; Belongs to the potassium channel family. (495 aa)
CALCACalcitonin related polypeptide alpha. (140 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa)
TPRG1LTumor protein p63-regulated gene 1-like protein. (272 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (468 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (146 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (979 aa)
CASRCalcium sensing receptor. (1078 aa)
UCNUrocortin. (124 aa)
FMR1Fragile X mental retardation 1 protein isoform ISO1. (632 aa)
GIT1GIT ArfGAP 1. (794 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (467 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform 4. (534 aa)
BIN1Bridging integrator 1. (668 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
UNC13AUnc-13 homolog A. (1677 aa)
SRSF10RRM domain-containing protein. (261 aa)
CPLX4Complexin IV. (160 aa)
SLC18A2Solute carrier family 18 member A2. (517 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1031 aa)
SLC4A10Anion exchange protein. (1193 aa)
DIXDC1DIX domain containing 1. (683 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2306 aa)
GPER1G-protein coupled estrogen receptor 1; G-protein coupled estrogen receptor that binds to 17-beta- estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine [...] (375 aa)
EPHA4EPH receptor A4. (1008 aa)
SLC18A3Solute carrier family 18 member A3. (532 aa)
TSPOAP1TSPO associated protein 1. (1936 aa)
NMUNeuromedin U. (173 aa)
PCSK1Neuroendocrine convertase 1 isoform 1 preproprotein; Belongs to the peptidase S8 family. (749 aa)
PTPN9Protein tyrosine phosphatase non-receptor type 9. (593 aa)
AAK1AP2 associated kinase 1. (1198 aa)
UNC13CUnc-13 homolog C. (2216 aa)
LOC114672301ETS domain-containing protein. (488 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (445 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2 isoform KV3.2b; Belongs to the potassium channel family. (638 aa)
GHRHGrowth hormone releasing hormone. (108 aa)
SLC1A2Amino acid transporter. (611 aa)
SYNJ1Synaptojanin 1. (1614 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (757 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1069 aa)
NTSNeurotensin/neuromedin N. (170 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
ELK1ETS domain-containing protein Elk-1. (428 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2 isoform a; Belongs to the potassium channel family. (499 aa)
CDH8Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (743 aa)
MACO1Macoilin; Plays a role in the regulation of neuronal activity. (664 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (1388 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
NTSR1Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1215 aa)
SLC8A1J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
PRSS12Neurotrypsin; Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations; Belongs to the peptidase S1 family. (875 aa)
GAD1Glutamate decarboxylase 1 isoform GAD67. (594 aa)
BSNBassoon presynaptic cytomatrix protein. (3722 aa)
CPLX3Complexin III. (158 aa)
DMDUncharacterized protein. (3685 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (701 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
PDYNProenkephalin-B preproprotein. (253 aa)
PRRT2Proline-rich transmembrane protein 2 isoform 1. (340 aa)
CALB2Uncharacterized protein. (272 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons protein 1. (444 aa)
PNOCPrepronociceptin. (201 aa)
PENKProenkephalin. (300 aa)
MMEMembrane metalloendopeptidase. (750 aa)
SLC4A8Anion exchange protein. (1093 aa)
KCNC1BTB domain-containing protein; Belongs to the potassium channel family. (585 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (542 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
GCH1GTP cyclohydrolase 1. (250 aa)
THTyrosine hydroxylase. (501 aa)
SLC32A1Vesicular inhibitory amino acid transporter. (525 aa)
SCGNSecretagogin, EF-hand calcium binding protein. (276 aa)
SCRG1Stimulator of chondrogenesis 1. (98 aa)
TNNTenascin N. (1299 aa)
FLRT1Fibronectin leucine rich transmembrane protein 1. (674 aa)
SNCBBeta-synuclein; Belongs to the synuclein family. (139 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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