STRINGSTRING
KAT5 KAT5 TBX3 TBX3 XKR8 XKR8 TNFSF14 TNFSF14 IL18 IL18 BTG1 BTG1 BMP4 BMP4 TRIP4 TRIP4 GDF3 GDF3 SOX9 SOX9 MYOG MYOG RANBP3L RANBP3L SMARCD3 SMARCD3 DDIT3 DDIT3 CCL17 CCL17 SOX8 SOX8 CSRP3 CSRP3 EID2B EID2B SMARCC2 SMARCC2 AKIRIN1 AKIRIN1 TNF TNF DPF3 DPF3 MAP3K5 MAP3K5 TMEM182 TMEM182 ID3 ID3 SMARCD2 SMARCD2 ZFP36L1 ZFP36L1 CXCL9 CXCL9 MEF2C MEF2C PRICKLE1 PRICKLE1 LOC716527 LOC716527 F7FN09_MACMU F7FN09_MACMU TGFB1 TGFB1 DLL1 DLL1 ZFHX3 ZFHX3 CXCL10 CXCL10 BBS5 BBS5 ANKRD2 ANKRD2 LRRC8A LRRC8A PBRM1 PBRM1 NOTCH1 NOTCH1 SOSTDC1 SOSTDC1 ARID2 ARID2 PPARD PPARD PHF10 PHF10 SMARCA2 SMARCA2 NMRK2 NMRK2 CMTM5 CMTM5 SOX4 SOX4 MSTN MSTN IGFBP3 IGFBP3 BOC BOC MYOCD MYOCD ARID1A ARID1A FLOT2 FLOT2 SMARCA4 SMARCA4 MYF5 MYF5 MYF6 MYF6 RBM24 RBM24 SMARCC1 SMARCC1 SMARCB1 SMARCB1 MAPK14 MAPK14 SMYD1 SMYD1 CDON CDON ACTL6B ACTL6B HIF1AN HIF1AN SMARCD1 SMARCD1 MYOD1 MYOD1 CXCL14 CXCL14 PLCB1 PLCB1 SMARCE1 SMARCE1 MBNL3 MBNL3 ARID1B ARID1B CAPN3 CAPN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa)
TBX3T-box transcription factor 3. (743 aa)
XKR8XK-related protein. (401 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
BTG1Protein BTG1. (171 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TRIP4Thyroid hormone receptor interactor 4. (581 aa)
GDF3Growth differentiation factor 3. (364 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
MYOGMyogenin. (249 aa)
RANBP3LRanBD1 domain-containing protein. (490 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (533 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa)
CCL17C-C motif chemokine 17; Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (91 aa)
SOX8SRY-box transcription factor 8. (617 aa)
CSRP3Cysteine and glycine rich protein 3. (253 aa)
EID2BEP300-interacting inhibitor of differentiation 2B. (161 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1244 aa)
AKIRIN1Akirin-1 isoform 1. (193 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
DPF3Double PHD fingers 3. (410 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1483 aa)
TMEM182Uncharacterized protein. (229 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (470 aa)
ZFP36L1ZFP36 ring finger protein like 1. (344 aa)
CXCL9C-X-C motif chemokine ligand 9. (201 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform 1. (473 aa)
PRICKLE1Prickle planar cell polarity protein 1. (848 aa)
LOC716527Flotillin-2. (428 aa)
F7FN09_MACMUAnti_prolifrtn domain-containing protein. (161 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ZFHX3Zinc finger homeobox 3. (3716 aa)
CXCL10C-X-C motif chemokine 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (98 aa)
BBS5Kelch like family member 41. (606 aa)
ANKRD2Ankyrin repeat domain 2. (532 aa)
LRRC8ALeucine-rich repeat-containing protein 8A. (810 aa)
PBRM1Polybromo 1. (1655 aa)
NOTCH1Notch receptor 1. (2556 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform 1. (441 aa)
PHF10PHD finger protein 10. (563 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1586 aa)
NMRK2Nicotinamide riboside kinase 2. (235 aa)
CMTM5CKLF like MARVEL transmembrane domain containing 5. (231 aa)
SOX4Transcription factor SOX. (467 aa)
MSTNGrowth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa)
IGFBP3Insulin-like growth factor-binding protein 3 isoform b. (291 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1115 aa)
MYOCDMyocardin. (986 aa)
ARID1AAT-rich interaction domain 1A. (2287 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MYF6Myogenic factor 6. (242 aa)
RBM24RNA binding motif protein 24. (178 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1132 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SMYD1SET and MYND domain containing 1. (490 aa)
CDONCell adhesion associated, oncogene regulated. (1339 aa)
ACTL6BActin like 6B; Belongs to the actin family. (449 aa)
HIF1ANHypoxia inducible factor 1 subunit alpha inhibitor. (397 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (603 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
CXCL14C-X-C motif chemokine ligand 14. (119 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
SMARCE1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1. (411 aa)
MBNL3Muscleblind like splicing regulator 3. (369 aa)
ARID1BAT-rich interaction domain 1B. (2428 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (821 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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