(13 nodes) Positive regulation of glycogen biosynthetic process network (Macaca mulatta)

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Your Input:
	PTH	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
	IGF1	Insulin like growth factor 1. (208 aa)
	SORBS1	Sorbin and SH3 domain containing 1. (1551 aa)
	PPP1R3E	Protein phosphatase 1 regulatory subunit 3E. (279 aa)
	IRS2	Insulin receptor substrate 2. (1394 aa)
	IRS1	Insulin receptor substrate 1. (1253 aa)
	INSR	Insulin receptor subunit alpha; Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src-homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosine residues, including the p85 regulatory subunit of PI3K and SHP2. Phosphorylation of IRSs proteins lea [...] (1279 aa)
	EPM2AIP1	EPM2A interacting protein 1. (602 aa)
	GCK	Phosphotransferase. (466 aa)
	AKT2	AKT serine/threonine kinase 2. (594 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	DYRK2	Dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform 2. (601 aa)
	IGF2	Insulin like growth factor 2. (244 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSMMUP00000061388	ENSMMUP00000059674	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	AKT serine/threonine kinase 2.	0.968
AKT1	IGF1	ENSMMUP00000061388	ENSMMUP00000002988	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin like growth factor 1.	0.691
AKT1	IGF2	ENSMMUP00000061388	ENSMMUP00000075297	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin like growth factor 2.	0.444
AKT1	IRS1	ENSMMUP00000061388	ENSMMUP00000045227	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin receptor substrate 1.	0.705
AKT1	IRS2	ENSMMUP00000061388	ENSMMUP00000028694	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin receptor substrate 2.	0.623
AKT2	AKT1	ENSMMUP00000059674	ENSMMUP00000061388	AKT serine/threonine kinase 2.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.968
AKT2	IGF1	ENSMMUP00000059674	ENSMMUP00000002988	AKT serine/threonine kinase 2.	Insulin like growth factor 1.	0.534
AKT2	IRS1	ENSMMUP00000059674	ENSMMUP00000045227	AKT serine/threonine kinase 2.	Insulin receptor substrate 1.	0.722
AKT2	IRS2	ENSMMUP00000059674	ENSMMUP00000028694	AKT serine/threonine kinase 2.	Insulin receptor substrate 2.	0.636
GCK	IGF1	ENSMMUP00000051138	ENSMMUP00000002988	Phosphotransferase.	Insulin like growth factor 1.	0.419
GCK	IRS1	ENSMMUP00000051138	ENSMMUP00000045227	Phosphotransferase.	Insulin receptor substrate 1.	0.469
GCK	IRS2	ENSMMUP00000051138	ENSMMUP00000028694	Phosphotransferase.	Insulin receptor substrate 2.	0.547
IGF1	AKT1	ENSMMUP00000002988	ENSMMUP00000061388	Insulin like growth factor 1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.691
IGF1	AKT2	ENSMMUP00000002988	ENSMMUP00000059674	Insulin like growth factor 1.	AKT serine/threonine kinase 2.	0.534
IGF1	GCK	ENSMMUP00000002988	ENSMMUP00000051138	Insulin like growth factor 1.	Phosphotransferase.	0.419
IGF1	IGF2	ENSMMUP00000002988	ENSMMUP00000075297	Insulin like growth factor 1.	Insulin like growth factor 2.	0.975
IGF1	INSR	ENSMMUP00000002988	ENSMMUP00000045695	Insulin like growth factor 1.	Insulin receptor subunit alpha; Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src-homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosine residues, including the p85 regulatory subunit of PI3K and SHP2. Phosphorylation of IRSs proteins lea [...]	0.970
IGF1	IRS1	ENSMMUP00000002988	ENSMMUP00000045227	Insulin like growth factor 1.	Insulin receptor substrate 1.	0.930
IGF1	IRS2	ENSMMUP00000002988	ENSMMUP00000028694	Insulin like growth factor 1.	Insulin receptor substrate 2.	0.867
IGF1	PTH	ENSMMUP00000002988	ENSMMUP00000064726	Insulin like growth factor 1.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.699