STRINGSTRING
OOEP OOEP INO80D INO80D SLF1 SLF1 BRD8 BRD8 ARID1B ARID1B INO80B INO80B FAM168A FAM168A BCL7C BCL7C DPF1 DPF1 SMARCE1 SMARCE1 RNF168 RNF168 DHX9 DHX9 FH FH EYA4 EYA4 SMARCD1 SMARCD1 ACTL6B ACTL6B WRAP53 WRAP53 SMARCB1 SMARCB1 SMARCC1 SMARCC1 LOC705671 LOC705671 ACTL6A ACTL6A NPAS2 NPAS2 KHDC3L KHDC3L MCRS1 MCRS1 MGMT MGMT SMARCA4 SMARCA4 UBE2V2 UBE2V2 BCL7A BCL7A ARID1A ARID1A EYA3 EYA3 SHLD2 SHLD2 HDAC10 HDAC10 RAD51AP1 RAD51AP1 SMARCA2 SMARCA2 PHF10 PHF10 HELQ HELQ PRKDC PRKDC ARID2 ARID2 PBRM1 PBRM1 EP400 EP400 SETMAR SETMAR FANCB FANCB ERCC6 ERCC6 TMEM161A TMEM161A ACTR8 ACTR8 FOXM1 FOXM1 FUS FUS KAT5 KAT5 SIRT6 SIRT6 TRIM28 TRIM28 INO80E INO80E POGZ POGZ ERCC8 ERCC8 PARP1 PARP1 TIMELESS TIMELESS PARP3 PARP3 TFPT TFPT EPC2 EPC2 PRKCG PRKCG PNKP PNKP SPIRE2 SPIRE2 UIMC1 UIMC1 F6VHV6_MACMU F6VHV6_MACMU BRCA1 BRCA1 ZCWPW1 ZCWPW1 SIRT1 SIRT1 RPS3 RPS3 EYA2 EYA2 RUVBL1 RUVBL1 DDX11 DDX11 DMAP1 DMAP1 MAD2L2 MAD2L2 SLF2 SLF2 ACTG1 ACTG1 WDR48 WDR48 MRGBP MRGBP BRCC3 BRCC3 EGFR EGFR MMS19 MMS19 ABRAXAS1 ABRAXAS1 RBBP8 RBBP8 SMARCD2 SMARCD2 UCHL5 UCHL5 YEATS4 YEATS4 UBE2N UBE2N EYA1 EYA1 MBTD1 MBTD1 TRRAP TRRAP ACTB ACTB FGF10 FGF10 DPF3 DPF3 WAS WAS NFRKB NFRKB FAM178B FAM178B PARP9 PARP9 ENSMMUP00000058534 ENSMMUP00000058534 SMARCC2 SMARCC2 MRNIP MRNIP SPIDR SPIDR SMCHD1 SMCHD1 ENSMMUP00000061983 ENSMMUP00000061983 ENSMMUP00000062445 ENSMMUP00000062445 PCNA PCNA VPS72 VPS72 KMT5C KMT5C RIF1 RIF1 ENSMMUP00000063480 ENSMMUP00000063480 PIAS4 PIAS4 ENSMMUP00000063857 ENSMMUP00000063857 DTX3L DTX3L ENSMMUP00000064422 ENSMMUP00000064422 CEBPG CEBPG ENSMMUP00000064847 ENSMMUP00000064847 BABAM1 BABAM1 MFSD11 MFSD11 SHLD3 SHLD3 ENSMMUP00000066721 ENSMMUP00000066721 CCDC117 CCDC117 ENSMMUP00000067093 ENSMMUP00000067093 HDGFL2 HDGFL2 FMN2 FMN2 ENSMMUP00000068036 ENSMMUP00000068036 ENSMMUP00000068718 ENSMMUP00000068718 RUVBL2 RUVBL2 ACTR2 ACTR2 MEAF6 MEAF6 CCND2 CCND2 ENSMMUP00000070668 ENSMMUP00000070668 INO80 INO80 SMARCD3 SMARCD3 BABAM2 BABAM2 ENSMMUP00000071941 ENSMMUP00000071941 ENSMMUP00000072510 ENSMMUP00000072510 SPIRE1 SPIRE1 ING3 ING3 ENSMMUP00000073070 ENSMMUP00000073070 MORF4L2 MORF4L2 ENSMMUP00000073151 ENSMMUP00000073151 ENSMMUP00000074181 ENSMMUP00000074181 ENSMMUP00000074362 ENSMMUP00000074362 ENSMMUP00000074969 ENSMMUP00000074969 ENSMMUP00000075287 ENSMMUP00000075287 ENSMMUP00000077180 ENSMMUP00000077180 KMT5B KMT5B SHLD1 SHLD1 ENSMMUP00000078409 ENSMMUP00000078409 LOC114669758 LOC114669758 ENSMMUP00000078516 ENSMMUP00000078516 EPC1 EPC1 BCL7B BCL7B ENSMMUP00000079633 ENSMMUP00000079633 ENSMMUP00000079943 ENSMMUP00000079943
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OOEPOocyte expressed protein. (149 aa)
INO80DINO80 complex subunit D. (1027 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1059 aa)
BRD8Bromodomain containing 8. (1235 aa)
ARID1BAT-rich interaction domain 1B. (2428 aa)
INO80BINO80 complex subunit B. (356 aa)
FAM168AUncharacterized protein. (244 aa)
BCL7CUncharacterized protein. (242 aa)
DPF1Zinc finger protein neuro-d4 isoform a. (414 aa)
SMARCE1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1. (411 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (661 aa)
DHX9ATP-dependent RNA helicase A. (1275 aa)
FHFumarate hydratase, mitochondrial. (510 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (648 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (603 aa)
ACTL6BActin like 6B; Belongs to the actin family. (449 aa)
WRAP53Telomerase Cajal body protein 1. (548 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1132 aa)
LOC705671Uncharacterized protein. (398 aa)
ACTL6AActin-like protein 6A isoform 1; Belongs to the actin family. (429 aa)
NPAS2Neuronal PAS domain-containing protein 2. (824 aa)
KHDC3LKH domain containing 3 like, subcortical maternal complex member. (206 aa)
MCRS1Microspherule protein 1. (475 aa)
MGMTMethylated-DNA--protein-cysteine methyltransferase. (238 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
BCL7AB-cell CLL/lymphoma 7 protein family member A isoform a. (231 aa)
ARID1AAT-rich interaction domain 1A. (2287 aa)
EYA3Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (579 aa)
SHLD2FAM35_C domain-containing protein. (881 aa)
HDAC10Histone deacetylase 10. (939 aa)
RAD51AP1RAD51 associated protein 1. (352 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1586 aa)
PHF10PHD finger protein 10. (563 aa)
HELQHelicase, POLQ like. (1101 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
PBRM1Polybromo 1. (1655 aa)
EP400E1A binding protein p400. (3045 aa)
SETMARSET domain and mariner transposase fusion gene. (684 aa)
FANCBFA complementation group B. (858 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (2061 aa)
TMEM161ATransmembrane protein 161A. (479 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
FOXM1Forkhead box protein M1 isoform 2. (770 aa)
FUSTripartite motif containing 72. (534 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa)
SIRT6NAD-dependent deacetylase sirtuin-6. (355 aa)
TRIM28Tripartite motif containing 28. (834 aa)
INO80EUncharacterized protein. (243 aa)
POGZPogo transposable element derived with ZNF domain. (1492 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (375 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
TIMELESSTimeless circadian regulator. (1204 aa)
PARP3Poly [ADP-ribose] polymerase. (532 aa)
TFPTTCF3 fusion partner. (253 aa)
EPC2Enhancer of polycomb homolog. (783 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
PNKPPolynucleotide kinase 3'-phosphatase. (532 aa)
SPIRE2Spire type actin nucleation factor 2. (714 aa)
UIMC1Ubiquitin interaction motif containing 1. (719 aa)
F6VHV6_MACMUReverse transcriptase domain-containing protein. (863 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1884 aa)
ZCWPW1Zinc finger CW-type and PWWP domain containing 1. (649 aa)
SIRT1Sirtuin 1. (743 aa)
RPS340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (538 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
DDX11DEAD/H-box helicase 11. (970 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (612 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (212 aa)
SLF2Uncharacterized protein. (1187 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
WDR48WD repeat domain 48. (745 aa)
MRGBPMRG domain binding protein. (204 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (291 aa)
EGFREpidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
ABRAXAS1BRCA1-A complex subunit Abraxas. (409 aa)
RBBP8Uncharacterized protein. (898 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (470 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (472 aa)
YEATS4YEATS domain-containing protein 4. (227 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
MBTD1Mbt domain containing 1. (754 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3873 aa)
ACTBUncharacterized protein. (421 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
DPF3Double PHD fingers 3. (410 aa)
WASWASP actin nucleation promoting factor. (503 aa)
NFRKBNuclear factor related to kappaB binding protein. (1433 aa)
FAM178BFamily with sequence similarity 178 member B. (679 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (818 aa)
ENSMMUP00000058534UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1244 aa)
MRNIPMRN complex interacting protein. (346 aa)
SPIDRScaffold protein involved in DNA repair. (946 aa)
SMCHD1Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (2005 aa)
ENSMMUP00000061983Uncharacterized protein. (134 aa)
ENSMMUP00000062445Reverse transcriptase domain-containing protein. (1070 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
VPS72Vacuolar protein sorting-associated protein 72 homolog. (364 aa)
KMT5CLysine methyltransferase 5C. (461 aa)
RIF1Replication timing regulatory factor 1. (2466 aa)
ENSMMUP00000063480Reverse transcriptase domain-containing protein. (765 aa)
PIAS4Protein inhibitor of activated STAT 4. (561 aa)
ENSMMUP00000063857DUF1725 domain-containing protein. (120 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (740 aa)
ENSMMUP00000064422Reverse transcriptase domain-containing protein. (860 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (150 aa)
ENSMMUP00000064847Reverse transcriptase domain-containing protein. (860 aa)
BABAM1BRISC and BRCA1-A complex member 1. (329 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
SHLD3Shieldin complex subunit 3. (250 aa)
ENSMMUP00000066721Reverse transcriptase domain-containing protein. (1160 aa)
CCDC117Coiled-coil domain containing 117. (279 aa)
ENSMMUP00000067093Reverse transcriptase domain-containing protein. (873 aa)
HDGFL2LEDGF domain-containing protein. (680 aa)
FMN2Formin 2. (1833 aa)
ENSMMUP00000068036Uncharacterized protein. (134 aa)
ENSMMUP00000068718Reverse transcriptase domain-containing protein. (1075 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (497 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
MEAF6MYST/Esa1 associated factor 6. (203 aa)
CCND2Uncharacterized protein. (353 aa)
ENSMMUP00000070668Reverse transcriptase domain-containing protein. (878 aa)
INO80Putative DNA helicase INO80 complex-like protein 1. (1556 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (533 aa)
BABAM2BRISC and BRCA1 A complex member 2. (423 aa)
ENSMMUP00000071941Reverse transcriptase domain-containing protein. (1177 aa)
ENSMMUP00000072510Reverse transcriptase domain-containing protein. (1125 aa)
SPIRE1Spire type actin nucleation factor 1. (815 aa)
ING3Inhibitor of growth protein. (418 aa)
ENSMMUP00000073070Reverse transcriptase domain-containing protein. (1117 aa)
MORF4L2Mortality factor 4 like 2. (288 aa)
ENSMMUP00000073151zf-H2C2 domain-containing protein. (185 aa)
ENSMMUP00000074181Reverse transcriptase domain-containing protein. (730 aa)
ENSMMUP00000074362Reverse transcriptase domain-containing protein. (809 aa)
ENSMMUP00000074969Endo/exonuclease/phosphatase domain-containing protein. (162 aa)
ENSMMUP00000075287Reverse transcriptase domain-containing protein. (917 aa)
ENSMMUP00000077180Reverse transcriptase domain-containing protein. (882 aa)
KMT5BHistone-lysine N-methyltransferase SUV420H1 isoform 1. (885 aa)
SHLD1Shieldin complex subunit 1. (228 aa)
ENSMMUP00000078409Reverse transcriptase domain-containing protein. (850 aa)
LOC114669758Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (440 aa)
ENSMMUP00000078516Endo/exonuclease/phosphatase domain-containing protein. (185 aa)
EPC1Enhancer of polycomb homolog. (836 aa)
BCL7BUncharacterized protein. (251 aa)
ENSMMUP00000079633FAM35_C domain-containing protein. (120 aa)
ENSMMUP00000079943Reverse transcriptase domain-containing protein. (887 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (22%) [HD]