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| | THNSL1 | Threonine synthase-like 1. (743 aa) |
| | UPB1 | Beta-ureidopropionase 1. (386 aa) |
| | FADS3 | Fatty acid desaturase 3. (445 aa) |
| | QKI | KH domain-containing protein. (333 aa) |
| | ASS1 | Argininosuccinate synthase. (412 aa) |
| | SUGCT | Succinyl-CoA:glutarate-CoA transferase. (470 aa) |
| | OSBP | Oxysterol-binding protein; Belongs to the OSBP family. (805 aa) |
| | OSBPL6 | Oxysterol-binding protein; Belongs to the OSBP family. (967 aa) |
| | CRABP2 | Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa) |
| | ABHD1 | Abhydrolase domain containing 1. (405 aa) |
| | DEGS1 | Sphingolipid delta(4)-desaturase DES1. (323 aa) |
| | GAMT | RMT2 domain-containing protein. (268 aa) |
| | ALDH18A1 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa) |
| | HSD3B7 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7. (440 aa) |
| | HSD17B8 | Estradiol 17-beta-dehydrogenase 8. (261 aa) |
| | TBXAS1 | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa) |
| | ACSM1 | Acyl-CoA synthetase medium chain family member 1. (577 aa) |
| | OSBPL1A | Oxysterol-binding protein; Belongs to the OSBP family. (949 aa) |
| | ABHD3 | Abhydrolase domain-containing protein 3. (409 aa) |
| | CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa) |
| | LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (498 aa) |
| | MCAT | Malonyl-CoA-acyl carrier protein transacylase, mitochondrial isoform a. (390 aa) |
| | SCP2 | Non-specific lipid-transfer protein isoform 1 proprotein; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa) |
| | ALOX5AP | Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family. (218 aa) |
| | GOT2 | Aspartate aminotransferase. (430 aa) |
| | SLC1A3 | Amino acid transporter. (549 aa) |
| | APIP | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | ALDH1A3 | Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | ASAH2 | Neutral ceramidase. (780 aa) |
| | XBP1 | X-box binding protein 1. (376 aa) |
| | LOC713683 | Lipoxygenase domain-containing protein. (412 aa) |
| | ILVBL | IlvB acetolactate synthase like; Belongs to the TPP enzyme family. (660 aa) |
| | THNSL2 | Threonine synthase like 2. (492 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | PCBD1 | Pterin-4-alpha-carbinolamine dehydratase. (104 aa) |
| | ACSM5 | Acyl-CoA synthetase medium chain family member 5. (580 aa) |
| | LOC696244 | Uncharacterized protein. (581 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform a. (294 aa) |
| | HAO1 | Hydroxyacid oxidase 1. (370 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2332 aa) |
| | LOC100426497 | Uncharacterized protein; Belongs to the peptidase C14A family. (174 aa) |
| | BHMT | Betaine--homocysteine S-methyltransferase 2. (470 aa) |
| | DAGLB | Diacylglycerol lipase beta. (747 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1529 aa) |
| | GSTM2 | Uncharacterized protein. (248 aa) |
| | PNPLA8 | Calcium-independent phospholipase A2-gamma isoform 1. (782 aa) |
| | PSAT1 | Phosphoserine aminotransferase. (378 aa) |
| | PAH | Phenylalanine hydroxylase. (473 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (280 aa) |
| | GAD2 | Glutamate decarboxylase 2. (608 aa) |
| | LTC4S | Leukotriene C4 synthase. (150 aa) |
| | PRXL2B | Peroxiredoxin like 2B. (206 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (745 aa) |
| | FASN | Fatty acid synthase. (2576 aa) |
| | PTGS1 | Prostaglandin-endoperoxide synthase 1. (599 aa) |
| | SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa) |
| | FADS1 | Fatty acid desaturase 1. (444 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1323 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa) |
| | OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa) |
| | GAD1 | Glutamate decarboxylase 1 isoform GAD67. (594 aa) |
| | LOC702239 | Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa) |
| | MTHFD2L | Uncharacterized protein. (347 aa) |
| | MECR | Trans-2-enoyl-CoA reductase, mitochondrial isoform a. (373 aa) |
| | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 isoform 1. (331 aa) |
| | CBR4 | Carbonyl reductase family member 4. (237 aa) |
| | EDN2 | Endothelin 2. (206 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) |
| | F7GAY0_MACMU | Thioesterase domain-containing protein. (185 aa) |
| | OLAH | Thioesterase domain-containing protein. (265 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | OSBPL3 | Oxysterol-binding protein; Belongs to the OSBP family. (887 aa) |
| | SRR | Serine racemase. (365 aa) |
| | PRG3 | Proteoglycan 3, pro eosinophil major basic protein 2. (225 aa) |
| | SLC27A5 | Solute carrier family 27 member 5. (690 aa) |
| | PTGES2 | Prostaglandin E synthase 2; Belongs to the GST superfamily. (377 aa) |
| | F7HPC6_MACMU | Aminotran_5 domain-containing protein. (120 aa) |
| | DHFR | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (187 aa) |
| | MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (725 aa) |
| | LOC721404 | Uncharacterized protein; Belongs to the cytochrome P450 family. (525 aa) |
| | PER2 | Period circadian regulator 2. (1254 aa) |
| | ACSBG2 | Acyl-CoA synthetase bubblegum family member 2. (637 aa) |
| | OSBPL7 | Oxysterol-binding protein; Belongs to the OSBP family. (842 aa) |
| | LIPG | Lipase G, endothelial type. (500 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) |
| | LOC702037 | Uncharacterized protein. (412 aa) |
| | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa) |
| | ALDH1A2 | Retinal dehydrogenase 2 isoform 1; Belongs to the aldehyde dehydrogenase family. (518 aa) |
| | RGN | Regucalcin. (299 aa) |
| | MTHFD1L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (976 aa) |
| | LOC709461 | Uncharacterized protein; Belongs to the cytochrome P450 family. (519 aa) |
| | AKR1A1 | Alcohol dehydrogenase [NADP+]. (325 aa) |
| | ALOX12B | Arachidonate 12-lipoxygenase, 12R type. (701 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (688 aa) |
| | SDSL | Serine dehydratase like. (329 aa) |
| | DPYD | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1034 aa) |
| | HACD1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa) |
| | NANP | N-acetylneuraminic acid phosphatase. (248 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1024 aa) |
| | ACSM4 | Acyl-CoA synthetase medium chain family member 4. (580 aa) |
| | F6ZGT2_MACMU | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (330 aa) |
| | HPGDS | Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | GLUL | Glutamine synthetase. (373 aa) |
| | GGT6 | Gamma-glutamyltransferase 6. (499 aa) |
| | TTC33 | Non-specific serine/threonine protein kinase. (581 aa) |
| | LIPH | Lipase domain-containing protein. (675 aa) |
| | BCAT2 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (388 aa) |
| | F6SNN4_MACMU | DHFR domain-containing protein. (187 aa) |
| | IDO1 | Indoleamine 2,3-dioxygenase 1. (403 aa) |
| | HACD3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (362 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | ARMC7 | Armadillo repeat-containing protein 7. (198 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1884 aa) |
| | SCD5 | Stearoyl-CoA desaturase 5 isoform a; Belongs to the fatty acid desaturase type 1 family. (330 aa) |
| | ALOX15 | Arachidonate 15-lipoxygenase. (662 aa) |
| | WDR37 | WD repeat domain 37. (486 aa) |
| | LDHC | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (343 aa) |
| | LOC705393 | FA_desaturase domain-containing protein. (370 aa) |
| | MTR | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1265 aa) |
| | KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (458 aa) |
| | MGST3 | Uncharacterized protein. (284 aa) |
| | GGT7 | Gamma-glutamyltransferase 7. (662 aa) |
| | DHRS9 | Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (378 aa) |
| | PYCR1 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (346 aa) |
| | PLA2G1B | Phospholipase A(2). (148 aa) |
| | PHGDH | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (548 aa) |
| | HSD17B10 | 3-hydroxyacyl-CoA dehydrogenase type-2 isoform 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa) |
| | ENSMMUP00000041619 | Uncharacterized protein. (319 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of very long chain saturated (VLC-SFA) and polyunsaturated (PUFA) fatty acids that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical r [...] (381 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | CYP8B1 | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (501 aa) |
| | GPX4 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (196 aa) |
| | LOC715687 | Uncharacterized protein. (218 aa) |
| | PCCB | Propionyl-CoA carboxylase subunit beta. (597 aa) |
| | SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (520 aa) |
| | ADRM1 | Oxysterol-binding protein; Belongs to the OSBP family. (854 aa) |
| | UGDH | UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa) |
| | PTGES3 | CS domain-containing protein. (181 aa) |
| | MTHFD1 | Uncharacterized protein. (1140 aa) |
| | AGXT2 | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (518 aa) |
| | ALOXE3 | Arachidonate lipoxygenase 3. (843 aa) |
| | AKR1C1 | Aldo_ket_red domain-containing protein. (323 aa) |
| | ACOT7 | Acyl-CoA thioesterase 7. (395 aa) |
| | MGLL | Monoglyceride lipase. (352 aa) |
| | PLP1 | Uncharacterized protein. (281 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | KYNU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (465 aa) |
| | CTH | Uncharacterized protein. (434 aa) |
| | CAD | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2306 aa) |
| | ABCD3 | ATP binding cassette subfamily D member 3. (672 aa) |
| | MTAP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (283 aa) |
| | HSDL1 | Inactive hydroxysteroid dehydrogenase-like protein 1 isoform a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | TECR | Uncharacterized protein. (374 aa) |
| | LTA4H | Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (611 aa) |
| | ENSMMUP00000050580 | CS domain-containing protein. (149 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | ENSMMUP00000051606 | Uncharacterized protein. (173 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (297 aa) |
| | ACLY | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1155 aa) |
| | LIPI | Lipase I. (460 aa) |
| | TECRL | Trans-2,3-enoyl-CoA reductase like. (363 aa) |
| | GLS2 | Glutaminase 2. (626 aa) |
| | HNF1A | HNF1 homeobox A. (657 aa) |
| | LIPC | Lipase C, hepatic type. (523 aa) |
| | ELOVL7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (283 aa) |
| | LGSN | Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (569 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa) |
| | FADS2 | Fatty acid desaturase 2. (499 aa) |
| | ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (370 aa) |
| | PARK7 | Protein DJ-1. (189 aa) |
| | GSTP1 | Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity); Belongs to the GST superfamily. Pi family. (274 aa) |
| | BCAT1 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (403 aa) |
| | SDS | PALP domain-containing protein. (344 aa) |
| | GLS | Glutaminase kidney isoform, mitochondrial isoform 1. (669 aa) |
| | GOT1L1 | Glutamic-oxaloacetic transaminase 1 like 1. (415 aa) |
| | MRI1 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (592 aa) |
| | AASS | Aminoadipate-semialdehyde synthase. (925 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (326 aa) |
| | CARNS1 | Carnosine synthase 1. (1208 aa) |
| | LOC699388 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | SCD | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (442 aa) |
| | LOC700936 | Uncharacterized protein. (564 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (723 aa) |
| | MREG | Peroxisomal trans-2-enoyl-CoA reductase. (414 aa) |
| | ACOT8 | Acyl-coenzyme A thioesterase 8. (319 aa) |
| | EDN1 | Preproendothelin-1. (211 aa) |
| | RPP14 | Hydroxyacyl-thioester dehydratase type 2. (168 aa) |
| | TMEM196 | Uncharacterized protein. (188 aa) |
| | TMED8 | Transmembrane p24 trafficking protein family member 8. (326 aa) |
| | SLC27A2 | Solute carrier family 27 member 2. (626 aa) |
| | NAIP | NLR family apoptosis inhibitory protein. (1403 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | ASL | RPOL4c domain-containing protein. (640 aa) |
| | PLA2G5 | Phospholipase A(2). (152 aa) |
| | GLUD1 | Glutamate dehydrogenase 1, mitochondrial; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (558 aa) |
| | GGT1 | Uncharacterized protein. (569 aa) |
| | CYP39A1 | Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (453 aa) |
| | ALDH1A1 | Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (527 aa) |
| | GATM | Glycine amidinotransferase, mitochondrial. (423 aa) |
| | CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (892 aa) |
| | CYP46A1 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (583 aa) |
| | PLA2G10 | Phospholipase A(2). (165 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (462 aa) |
| | HAAO | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (314 aa) |
| | CYP27A1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (584 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (334 aa) |
| | NOXRED1 | NADP dependent oxidoreductase domain containing 1. (359 aa) |
| | GGT5 | Gamma-glutamyltransferase 5. (586 aa) |
| | OAT | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (477 aa) |
| | PLA2G2F | Phospholipase A(2). (269 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2486 aa) |
| | HACD4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa) |
| | PSPH | Phosphoserine phosphatase. (225 aa) |
| | DHFR2 | DHFR domain-containing protein. (103 aa) |
| | ABAT | 4-aminobutyrate aminotransferase. (568 aa) |
| | BAAT | Bile acid-CoA:amino acid N-acyltransferase. (418 aa) |
| | HACD2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (254 aa) |
| | PTGDS | Prostaglandin-H2 D-isomerase; Belongs to the calycin superfamily. Lipocalin family. (190 aa) |
| | ACSF3 | Acyl-CoA synthetase family member 3. (582 aa) |
| | LOC698302 | OTCace_N domain-containing protein. (164 aa) |
| | ENSMMUP00000073051 | Elongation of very long chain fatty acids protein. (162 aa) |
| | PYCARD | Apoptosis-associated speck-like protein containing a CARD isoform a. (195 aa) |
| | MGST2 | Microsomal glutathione S-transferase 2 isoform 1. (147 aa) |
| | NAGS | N-acetylglutamate synthase. (566 aa) |
| | ASNSD1 | Glutamine amidotransferase type-2 domain-containing protein. (643 aa) |
| | GATD1 | Parkinson disease 7 domain-containing protein 1. (220 aa) |
| | PTGES | Prostaglandin E synthase. (214 aa) |
| | OTC | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (455 aa) |
| | ASNS | Asparagine synthetase [glutamine-hydrolyzing]. (561 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | ENOPH1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa) |
| | ACSM3 | Acyl-CoA synthetase medium chain family member 3. (596 aa) |
| | PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (780 aa) |
| | UROS | Uroporphyrinogen III synthase. (309 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (579 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | PCBD2 | Pterin-4 alpha-carbinolamine dehydratase 2. (122 aa) |
