STRINGSTRING
NOS3 NOS3 TIMP4 TIMP4 HCRTR2 HCRTR2 ASS1 ASS1 MAPK9 MAPK9 CLOCK CLOCK TNFRSF11A TNFRSF11A ENOX1 ENOX1 NCOR1 NCOR1 PML PML SLIT2 SLIT2 DRD4 DRD4 ADNP ADNP NFKB2 NFKB2 HNF1B HNF1B STAT5B STAT5B RACK1 RACK1 OPN4 OPN4 TH TH TYMS TYMS FZD4 FZD4 USP7 USP7 MAPK8 MAPK8 TRPM2 TRPM2 ID1 ID1 NLGN1 NLGN1 NOCT NOCT DHX9 DHX9 IMPDH2 IMPDH2 GPR176 GPR176 TPH1 TPH1 HUWE1 HUWE1 ZNF830 ZNF830 HNF4A HNF4A CRTC1 CRTC1 LOC695847 LOC695847 PTEN PTEN TP53 TP53 USP2 USP2 TOP2A TOP2A MTTP MTTP SIN3A SIN3A DDX5 DDX5 CDK5R1 CDK5R1 NPAS2 NPAS2 HDAC1 HDAC1 DTL DTL NR0B2 NR0B2 LHCGR LHCGR PRKAA2 PRKAA2 TNFAIP6 TNFAIP6 TOP1 TOP1 GDF10 GDF10 TGFB3 TGFB3 RORC RORC IGF1R IGF1R NTRK1 NTRK1 KIAA2013 KIAA2013 PLEKHA1 PLEKHA1 ENOX2 ENOX2 ADAMTS1 ADAMTS1 DNM1L DNM1L PPP1CC PPP1CC TYRO3 TYRO3 CYP1B1 CYP1B1 NR5A1 NR5A1 RELB RELB DRD2 DRD2 NGFR NGFR ID4 ID4 METTL3 METTL3 ATOH7 ATOH7 KDM5B KDM5B PRKDC PRKDC PAX4 PAX4 SIAH2 SIAH2 NCOA2 NCOA2 PPARA PPARA GRIN3A GRIN3A HOMER1 HOMER1 SUV39H2 SUV39H2 FSHR FSHR PTN PTN EREG EREG BHLHE40 BHLHE40 NAGLU NAGLU SCAPER SCAPER GAS2 GAS2 SP1 SP1 EGR1 EGR1 PTX3 PTX3 MYBBP1A MYBBP1A CIPC CIPC INHBA INHBA RBM4B RBM4B TEF TEF NRIP1 NRIP1 EP300 EP300 CIART CIART PPARG PPARG CCAR2 CCAR2 THRAP3 THRAP3 HNRNPD HNRNPD FBXW9 FBXW9 CSNK1E CSNK1E NTRK2 NTRK2 MTOR MTOR CRY1 CRY1 NHLH2 NHLH2 MC3R MC3R RAI1 RAI1 CARTPT CARTPT SERPINF1 SERPINF1 AMH AMH PAM PAM AGRP AGRP C2H3orf70 C2H3orf70 CSNK1D CSNK1D NMS NMS CAVIN3 CAVIN3 AHR AHR ADCY1 ADCY1 DDB1 DDB1 ESR1 ESR1 ENSMMUP00000069462 ENSMMUP00000069462 ATF4 ATF4 SLIT3 SLIT3 ARNTL ARNTL ATF5 ATF5 PROX1 PROX1 KDM2A KDM2A GPR157 GPR157 RPE65 RPE65 NKX2-1 NKX2-1 KCNH7 KCNH7 PROKR2 PROKR2 CREBBP CREBBP GPR149 GPR149 NR1D1 NR1D1 OGT OGT TGFB2 TGFB2 CRY2 CRY2 SPSB4 SPSB4 GFPT1 GFPT1 HTR7 HTR7 KAT2B KAT2B PTPRN PTPRN DBP DBP NAMPT NAMPT GSK3B GSK3B NUDT12 NUDT12 PPP1CA PPP1CA MTA1 MTA1 ZPBP2 ZPBP2 HEBP1 HEBP1 RESP18 RESP18 MTNR1A MTNR1A DYRK1A DYRK1A PROK2 PROK2 KLF10 KLF10 PER2 PER2 AANAT AANAT SFPQ SFPQ LOC702037 LOC702037 CUL4A CUL4A SUV39H1 SUV39H1 HES7 HES7 SIRT6 SIRT6 DDC DDC SRC SRC EZH2 EZH2 PPARGC1A PPARGC1A ENSMMUP00000060372 ENSMMUP00000060372 MAP2K6 MAP2K6 MDK MDK UBE3A UBE3A ROBO2 ROBO2 HDAC2 HDAC2 GABRB1 GABRB1 FSHB FSHB JUND JUND CBX3 CBX3 ADIPOQ ADIPOQ KDM5A KDM5A PRMT5 PRMT5 PER3 PER3 MMP19 MMP19 CASP2 CASP2 BHLHE41 BHLHE41 SREBF1 SREBF1 MMP2 MMP2 NFYA NFYA ID3 ID3 BTRC BTRC SETX SETX FBXW11 FBXW11 MYCBP2 MYCBP2 CLDN4 CLDN4 AFP AFP BMPR1B BMPR1B ID2 ID2 RORA RORA RORB RORB KDM8 KDM8 SGPL1 SGPL1 FBXW7 FBXW7 PIWIL2 PIWIL2 CCDC90B CCDC90B HAS2 HAS2 AXL AXL MAPK10 MAPK10 ENSMMUP00000041619 ENSMMUP00000041619 KDM5C KDM5C NONO NONO NCOR2 NCOR2 NR1D2 NR1D2 CREB1 CREB1 HNRNPU HNRNPU LGR4 LGR4 ROCK2 ROCK2 PSPC1 PSPC1 FAM155A FAM155A SIRT1 SIRT1 CDK1 CDK1 HDAC3 HDAC3 BTBD9 BTBD9 PRKCG PRKCG TTC33 TTC33 SRRD SRRD ARNTL2 ARNTL2 PASD1 PASD1 HLF HLF TIMELESS TIMELESS ATG7 ATG7 PER1 PER1 FBXL3 FBXL3 MAGED1 MAGED1 ZFHX3 ZFHX3 PPP1CB PPP1CB CDK5 CDK5 NPY5R NPY5R
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)
HCRTR2Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (444 aa)
ASS1Argininosuccinate synthase. (412 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CLOCKClock circadian regulator. (852 aa)
TNFRSF11ATNF receptor superfamily member 11a. (615 aa)
ENOX1Ecto-NOX disulfide-thiol exchanger 1. (687 aa)
NCOR1Nuclear receptor corepressor 1. (2442 aa)
PMLPromyelocytic leukemia protein. (882 aa)
SLIT2Slit guidance ligand 2. (1529 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (418 aa)
ADNPActivity dependent neuroprotector homeobox. (1123 aa)
NFKB2Nuclear factor kappa B subunit 2. (907 aa)
HNF1BHepatocyte nuclear factor 1-beta. (557 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
RACK1Guanine nucleotide binding protein beta polypeptide 2-like 1. (317 aa)
OPN4Opsin 4. (489 aa)
THTyrosine hydroxylase. (501 aa)
TYMSThymidylate synthetase. (313 aa)
FZD4Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1102 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1539 aa)
ID1DNA-binding protein inhibitor ID-1 isoform a. (154 aa)
NLGN1Neuroligin-1. (823 aa)
NOCTNocturnin. (408 aa)
DHX9ATP-dependent RNA helicase A. (1275 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (538 aa)
GPR176Putative G-protein coupled receptor 176. (515 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
HUWE1E3 ubiquitin-protein ligase HUWE1. (4374 aa)
ZNF830Zinc finger protein 830. (372 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
CRTC1CREB-regulated transcription coactivator 1 isoform 3. (650 aa)
LOC695847Uncharacterized protein. (183 aa)
PTENUncharacterized protein. (589 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (433 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (657 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa)
MTTPMicrosomal triglyceride transfer protein. (894 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (617 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
NPAS2Neuronal PAS domain-containing protein 2. (824 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (704 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
TNFAIP6Tumor necrosis factor-inducible gene 6 protein. (277 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
RORCRAR related orphan receptor C. (518 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
NTRK1Tyrosine-protein kinase receptor. (816 aa)
KIAA2013KIAA2013. (609 aa)
PLEKHA1Pleckstrin homology domain-containing family A member 1 isoform 1. (404 aa)
ENOX2Ecto-NOX disulfide-thiol exchanger 2 isoform a. (581 aa)
ADAMTS1A disintegrin and metalloproteinase with thrombospondin motifs 1 preproprotein. (967 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3. (890 aa)
CYP1B1Uncharacterized protein; Belongs to the cytochrome P450 family. (542 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (500 aa)
RELBRELB proto-oncogene, NF-kB subunit. (574 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
NGFRNerve growth factor receptor. (427 aa)
ID4DNA-binding protein inhibitor ID-4. (161 aa)
METTL3N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa)
ATOH7Atonal bHLH transcription factor 7. (152 aa)
KDM5BLysine demethylase 5B. (1562 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa)
PAX4Paired box 4. (343 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
NCOA2Nuclear receptor coactivator. (1468 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
HOMER1Homer scaffold protein 1. (374 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (410 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
PTNUncharacterized protein. (172 aa)
EREGProepiregulin. (169 aa)
BHLHE40Uncharacterized protein. (631 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
SCAPERS-phase cyclin A associated protein in the ER. (1400 aa)
GAS2Growth arrest-specific protein 2. (313 aa)
SP1Uncharacterized protein. (845 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (545 aa)
PTX3Pentraxin 3. (381 aa)
MYBBP1AMYB binding protein 1a. (1348 aa)
CIPCUncharacterized protein. (399 aa)
INHBAInhibin subunit beta A. (426 aa)
RBM4BRNA binding motif protein 4B. (371 aa)
TEFTEF transcription factor, PAR bZIP family member. (303 aa)
NRIP1Nuclear receptor interacting protein 1. (1216 aa)
EP300Histone acetyltransferase p300. (2414 aa)
CIARTCircadian associated repressor of transcription. (385 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
CCAR2P30 DBC protein. (920 aa)
THRAP3Thyroid hormone receptor-associated protein 3. (955 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D0 isoform a. (355 aa)
FBXW9F-box and WD repeat domain containing 9. (502 aa)
CSNK1EProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
NHLH2BHLH domain-containing protein. (135 aa)
MC3RMelanocortin 3 receptor. (323 aa)
RAI1Retinoic acid induced 1. (1954 aa)
CARTPTCART prepropeptide. (122 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
AMHAnti-Mullerian hormone. (561 aa)
PAMPeptidyl-glycine alpha-amidating monooxygenase isoform a preproprotein. (976 aa)
AGRPAgouti related neuropeptide. (132 aa)
C2H3orf70Uncharacterized protein. (250 aa)
CSNK1DProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (427 aa)
NMSNeuromedin S. (163 aa)
CAVIN3Protein kinase C delta-binding protein. (263 aa)
AHRUncharacterized protein. (848 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
ESR1Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
ENSMMUP00000069462Uncharacterized protein. (668 aa)
ATF4BZIP domain-containing protein. (351 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator-like protein 1 isoform a. (626 aa)
ATF5Activating transcription factor 5. (287 aa)
PROX1Prospero homeobox protein 1. (737 aa)
KDM2ALysine-specific demethylase 2A isoform a. (1162 aa)
GPR157G protein-coupled receptor 157. (335 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
NKX2-1NK2 homeobox 1. (448 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1529 aa)
PROKR2Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
CREBBPCREB-binding protein isoform a. (2442 aa)
GPR149G protein-coupled receptor 149. (731 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform 1. (1046 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CRY2Cryptochrome circadian regulator 2. (593 aa)
SPSB4SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
GFPT1Glutamine--fructose-6-phosphate transaminase 1. (799 aa)
HTR75-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (445 aa)
KAT2BLysine acetyltransferase 2B. (866 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (979 aa)
DBPD-box binding PAR bZIP transcription factor. (434 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
GSK3BGlycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily. (433 aa)
NUDT12Peroxisomal NADH pyrophosphatase NUDT12. (462 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (347 aa)
MTA1Metastasis associated 1. (726 aa)
ZPBP2Zona pellucida binding protein 2. (337 aa)
HEBP1Heme-binding protein 1. (189 aa)
RESP18Regulated endocrine specific protein 18. (216 aa)
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (352 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa)
PROK2Prokineticin 2. (129 aa)
KLF10Transforming growth factor-beta-inducible early growth response protein 1. (480 aa)
PER2Period circadian regulator 2. (1254 aa)
AANATSerotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. (248 aa)
SFPQSplicing factor, proline-and glutamine-rich. (707 aa)
LOC702037Uncharacterized protein. (412 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (423 aa)
HES7Hes family bHLH transcription factor 7. (253 aa)
SIRT6NAD-dependent deacetylase sirtuin-6. (355 aa)
DDCAromatic-L-amino-acid decarboxylase. (480 aa)
SRCTyrosine-protein kinase. (644 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (832 aa)
PPARGC1APPARG coactivator 1 alpha. (818 aa)
ENSMMUP00000060372Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (280 aa)
MAP2K6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa)
MDKMidkine. (143 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
ROBO2Roundabout guidance receptor 2. (1394 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (432 aa)
CBX3Chromobox protein homolog 3. (183 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (274 aa)
KDM5ALysine-specific demethylase 5A. (1690 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (633 aa)
PER3Period circadian regulator 3. (1178 aa)
MMP19Matrix metallopeptidase 19. (508 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
BHLHE41Basic helix-loop-helix family member e41. (482 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
MMP272 kDa type IV collagenase isoform a preproprotein. (660 aa)
NFYANuclear transcription factor Y subunit alpha isoform 1. (347 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
BTRCUncharacterized protein. (629 aa)
SETXSenataxin. (2721 aa)
FBXW11Uncharacterized protein. (563 aa)
MYCBP2MYC binding protein 2. (4682 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
AFPAlpha fetoprotein. (609 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ID2Inhibitor of DNA binding 2. (203 aa)
RORARAR related orphan receptor A. (555 aa)
RORBNuclear receptor ROR-beta. (459 aa)
KDM8Lysine demethylase 8. (416 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform 1. (707 aa)
PIWIL2Piwi like-2 protein; Belongs to the argonaute family. (973 aa)
CCDC90BCoiled-coil domain containing 90B. (305 aa)
HAS2Hyaluronan synthase 2. (552 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
ENSMMUP00000041619Uncharacterized protein. (319 aa)
KDM5CLysine-specific demethylase 5C isoform 1. (1560 aa)
NONOUncharacterized protein. (504 aa)
NCOR2Nuclear receptor corepressor 2. (2516 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2 isoform 1. (579 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (951 aa)
ROCK2Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
PSPC1Paraspeckle component 1. (523 aa)
FAM155AFamily with sequence similarity 155 member A. (457 aa)
SIRT1Sirtuin 1. (743 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
BTBD9BTB/POZ domain-containing protein 9 isoform a. (612 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
TTC33Non-specific serine/threonine protein kinase. (581 aa)
SRRDSRR1 domain containing. (325 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (636 aa)
PASD1PAS domain containing repressor 1. (757 aa)
HLFHepatic leukemia factor. (295 aa)
TIMELESSTimeless circadian regulator. (1204 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (770 aa)
PER1Vesicle-associated membrane protein 2. (1369 aa)
FBXL3F-box and leucine-rich repeat protein 3A. (428 aa)
MAGED1MAGE family member D1. (834 aa)
ZFHX3Zinc finger homeobox 3. (3716 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (339 aa)
CDK5Cyclin dependent kinase 5. (364 aa)
NPY5RG_PROTEIN_RECEP_F1_2 domain-containing protein. (455 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (22%) [HD]