STRINGSTRING
BCL11B BCL11B IHH IHH HOXC10 HOXC10 ATOH1 ATOH1 SUFU SUFU GSX1 GSX1 ASCL1 ASCL1 MYT1L MYT1L TBR1 TBR1 EPOP EPOP NOTCH3 NOTCH3 WNT1 WNT1 NOTCH1 NOTCH1 OLIG2 OLIG2 SMAD4 SMAD4 FOXN4 FOXN4 DLL1 DLL1 FOXG1 FOXG1 FEZF2 FEZF2 POU4F1 POU4F1 GATA2 GATA2 LHX3 LHX3 EHMT2 EHMT2 HOXD10 HOXD10 DBX1 DBX1 GBX1 GBX1 ID2 ID2 TGFBR1 TGFBR1 ENSMMUP00000052570 ENSMMUP00000052570 EYA1 EYA1 OLIG3 OLIG3 GSX2 GSX2 GLI2 GLI2 FKBP8 FKBP8 PRRX1 PRRX1 MNX1 MNX1 CTNNB1 CTNNB1 ISL2 ISL2 ISL1 ISL1 NRG1 NRG1 SHH SHH DLL4 DLL4 NKX2-2 NKX2-2 DMRTA2 DMRTA2 NKX2-1 NKX2-1 DLX1 DLX1 GLI3 GLI3 FEV FEV DLX2 DLX2 PROX1 PROX1 ZNF521 ZNF521 FOXA1 FOXA1 DMRT1 DMRT1 PTF1A PTF1A JAG2 JAG2 TLX3 TLX3 LBX1 LBX1 BMP4 BMP4 PAX6 PAX6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
HOXC10Homeobox protein Hox-C10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (342 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (500 aa)
GSX1GS homeobox 1. (264 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (238 aa)
MYT1LMyelin transcription factor 1-like protein. (1185 aa)
TBR1T-box brain transcription factor 1. (682 aa)
EPOPElongin BC and polycomb repressive complex 2 associated protein. (379 aa)
NOTCH3Notch receptor 3. (2321 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
NOTCH1Notch receptor 1. (2556 aa)
OLIG2Oligodendrocyte transcription factor 2. (323 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
FOXN4Forkhead box N4. (517 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
FOXG1Forkhead box G1. (489 aa)
FEZF2FEZ family zinc finger 2. (457 aa)
POU4F1POU domain protein. (423 aa)
GATA2GATA binding protein 2. (480 aa)
LHX3LIM homeobox 3. (402 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1266 aa)
HOXD10Homeobox D10. (340 aa)
DBX1Developing brain homeobox 1. (344 aa)
GBX1Gastrulation brain homeobox 1. (362 aa)
ID2Inhibitor of DNA binding 2. (203 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
ENSMMUP00000052570Uncharacterized protein. (108 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
OLIG3Oligodendrocyte transcription factor 3. (273 aa)
GSX2GS homeobox 2. (304 aa)
GLI2GLI family zinc finger 2. (1569 aa)
FKBP8Peptidylprolyl isomerase. (441 aa)
PRRX1Uncharacterized protein. (245 aa)
MNX1Motor neuron and pancreas homeobox 1. (404 aa)
CTNNB1Catenin beta-1. (781 aa)
ISL2ISL LIM homeobox 2. (359 aa)
ISL1ISL LIM homeobox 1. (413 aa)
NRG1Neuregulin 1. (700 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
NKX2-2Homeobox domain-containing protein. (451 aa)
DMRTA2DMRT like family A2. (538 aa)
NKX2-1NK2 homeobox 1. (448 aa)
DLX1Homeobox protein DLX-1 isoform 1. (255 aa)
GLI3GLI family zinc finger 3. (1580 aa)
FEVFEV transcription factor, ETS family member. (238 aa)
DLX2Distal-less homeobox 2. (344 aa)
PROX1Prospero homeobox protein 1. (737 aa)
ZNF521Zinc finger protein 521. (1311 aa)
FOXA1Fork-head domain-containing protein. (470 aa)
DMRT1DM domain-containing protein. (643 aa)
PTF1APancreas associated transcription factor 1a. (329 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1290 aa)
TLX3T cell leukemia homeobox 3. (338 aa)
LBX1Homeobox domain-containing protein. (281 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
PAX6Uncharacterized protein. (598 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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