(25 nodes) Regulation of axon regeneration network (Macaca mulatta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	KREMEN1	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (492 aa)
	STK24	Serine/threonine-protein kinase 24. (443 aa)
	PTEN	Uncharacterized protein. (589 aa)
	SPP1	Secreted phosphoprotein 1. (314 aa)
	PTPRS	Protein tyrosine phosphatase receptor type S. (1948 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	FLNA	Filamin-A isoform 2. (2647 aa)
	LRIG2	Leucine rich repeats and immunoglobulin like domains 2. (1083 aa)
	KIAA0319	KIAA0319. (1072 aa)
	PTN	Uncharacterized protein. (172 aa)
	KLF4	Kruppel like factor 4. (544 aa)
	RTN4R	Reticulon 4 receptor. (538 aa)
	FKBP1B	Peptidylprolyl isomerase. (108 aa)
	LOC721827	Uncharacterized protein; Belongs to the parvalbumin family. (109 aa)
	LOC114676724	Uncharacterized protein; Belongs to the parvalbumin family. (109 aa)
	PTPRF	Protein tyrosine phosphatase receptor type F. (1918 aa)
	TNR	Uncharacterized protein. (1358 aa)
	INPP5F	Inositol polyphosphate-5-phosphatase F. (1133 aa)
	RTN4RL1	Reticulon-4 receptor-like 1. (445 aa)
	RGMA	Repulsive guidance molecule BMP co-receptor a. (576 aa)
	EPHA4	EPH receptor A4. (1008 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (763 aa)
	CERS2	LAG1 longevity assurance homolog 2. (380 aa)
	SCARF1	Scavenger receptor class F member 1. (841 aa)
	GRN	Granulin precursor. (593 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRAF	PTEN	ENSMMUP00000044832	ENSMMUP00000011055	B-Raf proto-oncogene, serine/threonine kinase.	Uncharacterized protein.	0.778
FKBP1B	LOC114676724	ENSMMUP00000073980	ENSMMUP00000069358	Peptidylprolyl isomerase.	Uncharacterized protein; Belongs to the parvalbumin family.	0.402
FKBP1B	LOC721827	ENSMMUP00000073980	ENSMMUP00000071344	Peptidylprolyl isomerase.	Uncharacterized protein; Belongs to the parvalbumin family.	0.402
IGF1R	PTEN	ENSMMUP00000016141	ENSMMUP00000011055	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.675
IGF1R	PTPRF	ENSMMUP00000016141	ENSMMUP00000065413	Tyrosine-protein kinase receptor.	Protein tyrosine phosphatase receptor type F.	0.485
IGF1R	PTPRS	ENSMMUP00000016141	ENSMMUP00000015690	Tyrosine-protein kinase receptor.	Protein tyrosine phosphatase receptor type S.	0.413
INPP5F	PTEN	ENSMMUP00000061672	ENSMMUP00000011055	Inositol polyphosphate-5-phosphatase F.	Uncharacterized protein.	0.903
LOC114676724	FKBP1B	ENSMMUP00000069358	ENSMMUP00000073980	Uncharacterized protein; Belongs to the parvalbumin family.	Peptidylprolyl isomerase.	0.402
LOC721827	FKBP1B	ENSMMUP00000071344	ENSMMUP00000073980	Uncharacterized protein; Belongs to the parvalbumin family.	Peptidylprolyl isomerase.	0.402
PTEN	BRAF	ENSMMUP00000011055	ENSMMUP00000044832	Uncharacterized protein.	B-Raf proto-oncogene, serine/threonine kinase.	0.778
PTEN	IGF1R	ENSMMUP00000011055	ENSMMUP00000016141	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.675
PTEN	INPP5F	ENSMMUP00000011055	ENSMMUP00000061672	Uncharacterized protein.	Inositol polyphosphate-5-phosphatase F.	0.903
PTN	PTPRS	ENSMMUP00000080883	ENSMMUP00000015690	Uncharacterized protein.	Protein tyrosine phosphatase receptor type S.	0.530
PTPRF	IGF1R	ENSMMUP00000065413	ENSMMUP00000016141	Protein tyrosine phosphatase receptor type F.	Tyrosine-protein kinase receptor.	0.485
PTPRF	RTN4R	ENSMMUP00000065413	ENSMMUP00000075689	Protein tyrosine phosphatase receptor type F.	Reticulon 4 receptor.	0.436
PTPRF	RTN4RL1	ENSMMUP00000065413	ENSMMUP00000061646	Protein tyrosine phosphatase receptor type F.	Reticulon-4 receptor-like 1.	0.482
PTPRS	IGF1R	ENSMMUP00000015690	ENSMMUP00000016141	Protein tyrosine phosphatase receptor type S.	Tyrosine-protein kinase receptor.	0.413
PTPRS	PTN	ENSMMUP00000015690	ENSMMUP00000080883	Protein tyrosine phosphatase receptor type S.	Uncharacterized protein.	0.530
PTPRS	RTN4R	ENSMMUP00000015690	ENSMMUP00000075689	Protein tyrosine phosphatase receptor type S.	Reticulon 4 receptor.	0.498
PTPRS	RTN4RL1	ENSMMUP00000015690	ENSMMUP00000061646	Protein tyrosine phosphatase receptor type S.	Reticulon-4 receptor-like 1.	0.547