STRINGSTRING
WDR60 WDR60 TBX15 TBX15 EIF4A3 EIF4A3 TGFBR2 TGFBR2 COL2A1 COL2A1 FUZ FUZ MYF5 MYF5 FLVCR1 FLVCR1 TGFB3 TGFB3 HOXA1 HOXA1 MMP16 MMP16 MMP14 MMP14 FGF8 FGF8 CHST11 CHST11 IRX5 IRX5 MTHFD1L MTHFD1L HOXB8 HOXB8 GRHL2 GRHL2 SETD2 SETD2 NIPBL NIPBL OSR2 OSR2 HOXB1 HOXB1 NODAL NODAL SIX2 SIX2 WDR19 WDR19 ZEB1 ZEB1 DLG1 DLG1 SLC39A1 SLC39A1 HOXC9 HOXC9 SMAD3 SMAD3 PAX5 PAX5 MEGF8 MEGF8 HOXA4 HOXA4 HOXD10 HOXD10 DSCAML1 DSCAML1 HOXC11 HOXC11 HOXD9 HOXD9 SMAD2 SMAD2 FGFR2 FGFR2 MED12 MED12 ENSMMUP00000049472 ENSMMUP00000049472 RDH10 RDH10 SATB2 SATB2 TGFBR1 TGFBR1 TBX1 TBX1 EYA1 EYA1 TFAP2A TFAP2A HOXD11 HOXD11 SOX11 SOX11 OSR1 OSR1 PRRX1 PRRX1 CTNNB1 CTNNB1 HOXA11 HOXA11 SHOX2 SHOX2 ALX4 ALX4 HOXB5 HOXB5 HOXC4 HOXC4 GLI3 GLI3 DLX2 DLX2 HOXB9 HOXB9 HOXB7 HOXB7 HOXB4 HOXB4 RUNX2 RUNX2 WNT9B WNT9B HOXA5 HOXA5 HOXA2 HOXA2 HOXB2 HOXB2 HOXD4 HOXD4 HOXA3 HOXA3 PCGF2 PCGF2 GSC GSC ALX3 ALX3 HOXD3 HOXD3 HOXB6 HOXB6 FOXC2 FOXC2 SIX1 SIX1 BMP4 BMP4 MDFI MDFI SIX4 SIX4 IFT140 IFT140 BMP7 BMP7 COL11A1 COL11A1 TEAD4 TEAD4 NOG NOG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WDR60WD repeat domain 60. (1067 aa)
TBX15T-box transcription factor 15. (635 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
FUZFuzzy planar cell polarity protein. (445 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (555 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
HOXA1Homeobox protein Hox-1F. (335 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
MMP14Matrix metalloproteinase-14 preproprotein. (582 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
IRX5Iroquois homeobox 5. (694 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (976 aa)
HOXB8Homeobox B8. (242 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2565 aa)
NIPBLNipped-B protein. (2804 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
HOXB1Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily. (304 aa)
NODALNodal growth differentiation factor. (347 aa)
SIX2SIX homeobox 2. (292 aa)
WDR19WD_REPEATS_REGION domain-containing protein. (1348 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1126 aa)
DLG1Disks large homolog 1 isoform 2; Belongs to the MAGUK family. (926 aa)
SLC39A1Uncharacterized protein. (386 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PAX5Paired box 5. (407 aa)
MEGF8Multiple EGF like domains 8. (2789 aa)
HOXA4Homeobox A4. (320 aa)
HOXD10Homeobox D10. (340 aa)
DSCAML1DS cell adhesion molecule like 1. (2113 aa)
HOXC11Homeobox C11. (304 aa)
HOXD9Homeobox D9. (345 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
MED12Mediator complex subunit 12. (2178 aa)
ENSMMUP00000049472Uncharacterized protein. (370 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
SATB2DNA-binding protein SATB. (732 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
TBX1T-box transcription factor 1. (496 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
TFAP2ATranscription factor AP-2 alpha. (445 aa)
HOXD11Homeobox D11. (338 aa)
SOX11Transcription factor SOX. (441 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
PRRX1Uncharacterized protein. (245 aa)
CTNNB1Catenin beta-1. (781 aa)
HOXA11Homeobox A11. (311 aa)
SHOX2Short stature homeobox 2. (355 aa)
ALX4ALX homeobox 4. (409 aa)
HOXB5Homeobox B5. (269 aa)
HOXC4Homeobox protein Hox-3E. (264 aa)
GLI3GLI family zinc finger 3. (1580 aa)
DLX2Distal-less homeobox 2. (344 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
HOXB7Homeobox B7. (217 aa)
HOXB4Homeobox B4. (251 aa)
RUNX2RUNX family transcription factor 2. (647 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
HOXA5Homeobox A5. (381 aa)
HOXA2Homeobox A2. (374 aa)
HOXB2Homeobox B2. (356 aa)
HOXD4Homeobox D4. (255 aa)
HOXA3Homeobox A3. (443 aa)
PCGF2Polycomb group RING finger protein 2. (344 aa)
GSCGoosecoid homeobox. (259 aa)
ALX3ALX homeobox 3. (343 aa)
HOXD3Homeobox D3. (432 aa)
HOXB6Homeobox B6. (224 aa)
FOXC2Forkhead box C2. (471 aa)
SIX1SIX homeobox 1. (284 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
MDFIMyoD family inhibitor. (246 aa)
SIX4SIX homeobox 4. (772 aa)
IFT140Intraflagellar transport 140. (1462 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
COL11A1Collagen alpha-1(XI) chain isoform A preproprotein. (1806 aa)
TEAD4TUB like protein 3; Belongs to the TUB family. (728 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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