STRINGSTRING
FGF19 FGF19 OSR1 OSR1 TGFBR3L TGFBR3L GSK3B GSK3B PPP3R1 PPP3R1 CORO1C CORO1C EDN1 EDN1 WNT11 WNT11 WNT2 WNT2 CTNNB1 CTNNB1 SPRY1 SPRY1 HEY2 HEY2 ZFP64 ZFP64 ISL1 ISL1 TGFB2 TGFB2 NRG1 NRG1 EGK_08539 EGK_08539 LRP6 LRP6 FN1 FN1 SNAI1 SNAI1 RFLNB RFLNB TAPT1 TAPT1 SHH SHH SOX10 SOX10 NRTN NRTN BMP2 BMP2 ENSMMUP00000065918 ENSMMUP00000065918 ENSMMUP00000066500 ENSMMUP00000066500 PHOX2B PHOX2B PITX2 PITX2 ENSMMUP00000067976 ENSMMUP00000067976 WNT4 WNT4 ENSMMUP00000068054 ENSMMUP00000068054 WNT10A WNT10A SOX8 SOX8 BCL2 BCL2 ENSMMUP00000070232 ENSMMUP00000070232 OLFM1 OLFM1 CUL7 CUL7 RANBP3L RANBP3L TMEM100 TMEM100 HEYL HEYL EOMES EOMES SOX9 SOX9 GSC GSC EDN3 EDN3 FRZB FRZB CMC4 CMC4 WNT5A WNT5A FOXC2 FOXC2 ENSMMUP00000075843 ENSMMUP00000075843 TCF21 TCF21 ENG ENG EFNA1 EFNA1 BMP4 BMP4 TCOF1 TCOF1 OVOL2 OVOL2 MSX1 MSX1 EFNB1 EFNB1 ENSMMUP00000077734 ENSMMUP00000077734 DLG5 DLG5 KITLG KITLG TBX3 TBX3 PWWP2A PWWP2A BMPR1A BMPR1A AKNA AKNA ENSMMUP00000080573 ENSMMUP00000080573 SEMA3A SEMA3A ENSMMUP00000081054 ENSMMUP00000081054 EPB41L5 EPB41L5 ERBB4 ERBB4 FAM172A FAM172A TGFBR3 TGFBR3 WNT16 WNT16 TASOR TASOR HNRNPAB HNRNPAB BMP7 BMP7 KBTBD8 KBTBD8 DDX17 DDX17 AMER1 AMER1 FOXF2 FOXF2 SEMA4F SEMA4F FOXC1 FOXC1 NOG NOG GBX2 GBX2 SEMA4C SEMA4C SEMA6C SEMA6C SEMA4D SEMA4D EXT1 EXT1 PAX2 PAX2 DDX5 DDX5 TTL TTL SEMA5B SEMA5B SEMA4G SEMA4G HTR2B HTR2B SEMA3C SEMA3C RPS7 RPS7 SMO SMO MAPK1 MAPK1 TBX20 TBX20 FBXL17 FBXL17 FLNA FLNA CDH2 CDH2 RET RET FGF8 FGF8 SNAI2 SNAI2 LOXL2 LOXL2 NOTCH1 NOTCH1 JAG1 JAG1 SMAD4 SMAD4 NOTCH4 NOTCH4 ACVR1 ACVR1 SEMA3G SEMA3G GDNF GDNF WWTR1 WWTR1 PHACTR4 PHACTR4 ALDH1A2 ALDH1A2 TRIM28 TRIM28 NRP2 NRP2 SEMA3B SEMA3B SEMA5A SEMA5A RTN4 RTN4 SEMA3D SEMA3D FGFR1 FGFR1 WNT8A WNT8A ADAM15 ADAM15 PEF1 PEF1 SEMA6B SEMA6B TGFB1 TGFB1 SIX2 SIX2 SEMA4B SEMA4B SFRP1 SFRP1 SEMA6A SEMA6A HAND2 HAND2 EDNRA EDNRA RADIL RADIL CYP26C1 CYP26C1 NRP1 NRP1 LOXL3 LOXL3 ROCK2 ROCK2 SEMA4A SEMA4A SEMA3F SEMA3F F6UCW2_MACMU F6UCW2_MACMU HAS2 HAS2 DACT3 DACT3 MEF2C MEF2C CITED4 CITED4 LEF1 LEF1 ANXA6 ANXA6 OTUD5 OTUD5 SEMA7A SEMA7A ROCK1 ROCK1 FGFR2 FGFR2 HMGA2 HMGA2 SEMA3E SEMA3E CITED2 CITED2 RDH10 RDH10 EDNRB EDNRB KLHL12 KLHL12 TGFBR1 TGFBR1 TBX1 TBX1 MAPK3 MAPK3 FGF10 FGF10 NOLC1 NOLC1 HEY1 HEY1 SOX11 SOX11 HIF1A HIF1A STAT1 STAT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
TGFBR3LTransforming growth factor beta receptor 3 like. (312 aa)
GSK3BGlycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily. (433 aa)
PPP3R1Uncharacterized protein. (171 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (527 aa)
EDN1Preproendothelin-1. (211 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
CTNNB1Catenin beta-1. (781 aa)
SPRY1Uncharacterized protein. (343 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
ZFP64Zinc finger protein 64 isoform a. (681 aa)
ISL1ISL LIM homeobox 1. (413 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
NRG1Neuregulin 1. (700 aa)
EGK_08539Uncharacterized protein. (283 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
FN1Fibronectin isoform 1 preproprotein. (2477 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
RFLNBRefilin B. (216 aa)
TAPT1Transmembrane anterior posterior transformation 1. (790 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
SOX10SRY-box transcription factor 10. (467 aa)
NRTNNeurturin preproprotein. (197 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
ENSMMUP00000065918Uncharacterized protein. (117 aa)
ENSMMUP00000066500Uncharacterized protein. (236 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
PITX2Homeobox protein. (354 aa)
ENSMMUP00000067976Uncharacterized protein. (120 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ENSMMUP00000068054Uncharacterized protein. (102 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
SOX8SRY-box transcription factor 8. (617 aa)
BCL2BCL2 apoptosis regulator. (241 aa)
ENSMMUP00000070232Uncharacterized protein. (121 aa)
OLFM1Olfactomedin 1. (652 aa)
CUL7Cullin 7; Belongs to the cullin family. (1910 aa)
RANBP3LRanBD1 domain-containing protein. (490 aa)
TMEM100Transmembrane protein 100. (134 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (477 aa)
EOMESEomesodermin. (703 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
GSCGoosecoid homeobox. (259 aa)
EDN3Endothelin 3. (257 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
CMC4Uncharacterized protein. (92 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (462 aa)
FOXC2Forkhead box C2. (471 aa)
ENSMMUP00000075843Uncharacterized protein. (341 aa)
TCF21Transcription factor 21. (179 aa)
ENGEndoglin. (672 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TCOF1LisH domain-containing protein. (1652 aa)
OVOL2Transcription factor Ovo-like 2. (275 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
EFNB1EPH-related receptor tyrosine kinase ligand 2; Belongs to the ephrin family. (346 aa)
ENSMMUP00000077734Uncharacterized protein. (122 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1948 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (283 aa)
TBX3T-box transcription factor 3. (743 aa)
PWWP2APWWP domain containing 2A. (755 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
AKNAAT-hook transcription factor. (1439 aa)
ENSMMUP00000080573Uncharacterized protein. (121 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
ENSMMUP00000081054Uncharacterized protein. (321 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
FAM172AFamily with sequence similarity 172 member A. (466 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
TASORTranscription activation suppressor. (1612 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B isoform a. (332 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
KBTBD8Kelch repeat and BTB domain containing 8. (601 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (731 aa)
AMER1APC membrane recruitment protein 1. (1136 aa)
FOXF2Forkhead box F2. (446 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
FOXC1Forkhead box C1. (551 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
SEMA4CUncharacterized protein; Belongs to the semaphorin family. (833 aa)
SEMA6CSema domain-containing protein; Belongs to the semaphorin family. (962 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
PAX2Paired box 2. (418 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (617 aa)
TTLDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1135 aa)
SEMA5BSemaphorin 5B. (1113 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
SEMA3CSemaphorin-3C; Belongs to the semaphorin family. (751 aa)
RPS740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
TBX20T-box transcription factor TBX20. (447 aa)
FBXL17F-box and leucine rich repeat protein 17. (702 aa)
FLNAFilamin-A isoform 2. (2647 aa)
CDH2Cadherin-2 preproprotein; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SNAI2Protein snail-like protein 2. (268 aa)
LOXL2Lysyl oxidase-like protein 2. (774 aa)
NOTCH1Notch receptor 1. (2556 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
NOTCH4Notch receptor 4. (1997 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (782 aa)
GDNFGlial cell derived neurotrophic factor. (342 aa)
WWTR1WW domain containing transcription regulator 1. (432 aa)
PHACTR4Phosphatase and actin regulator. (817 aa)
ALDH1A2Retinal dehydrogenase 2 isoform 1; Belongs to the aldehyde dehydrogenase family. (518 aa)
TRIM28Tripartite motif containing 28. (834 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (925 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (748 aa)
SEMA5AUncharacterized protein. (1080 aa)
RTN4Reticulon. (1193 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (778 aa)
FGFR1Fibroblast growth factor receptor. (853 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
ADAM15ADAM metallopeptidase domain 15. (919 aa)
PEF1Uncharacterized protein. (283 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (948 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SIX2SIX homeobox 2. (292 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (831 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
HAND2BHLH domain-containing protein. (186 aa)
EDNRAUncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (427 aa)
RADILRap associating with DIL domain. (1071 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
LOXL3Lysyl oxidase like 3. (753 aa)
ROCK2Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
F6UCW2_MACMU40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
HAS2Hyaluronan synthase 2. (552 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (631 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform 1. (473 aa)
CITED4Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (232 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
ANXA6Annexin. (673 aa)
OTUD5OTU deubiquitinase 5. (566 aa)
SEMA7ASemaphorin-7A isoform 1 preproprotein; Belongs to the semaphorin family. (664 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (527 aa)
KLHL12BTB domain-containing protein. (606 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
TBX1T-box transcription factor 1. (496 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (702 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1 isoform a. (304 aa)
SOX11Transcription factor SOX. (441 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (826 aa)
STAT1Signal transducer and activator of transcription. (802 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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