(23 nodes) Animal organ maturation network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCHS1	Dachsous cadherin-related 1. (3221 aa)
	IGF1	Insulin like growth factor 1. (208 aa)
	RYR1	Ryanodine receptor 1. (4928 aa)
	GATA3	GATA binding protein 3. (444 aa)
	ZBTB16	Uncharacterized protein. (673 aa)
	PHOSPHO1	Phosphoethanolamine/phosphocholine phosphatase. (301 aa)
	ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif 7. (1691 aa)
	PHOSPHO2	Pyridoxal phosphate phosphatase PHOSPHO2. (241 aa)
	BMP2	Bone morphogenetic protein 2. (396 aa)
	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif 12. (1598 aa)
	PLXNB1	Plexin B1. (2140 aa)
	SNX10	Sorting nexin 10. (227 aa)
	RHOA	Ras homolog family member A. (209 aa)
	THBS3	Uncharacterized protein. (956 aa)
	CCDC154	Coiled-coil domain containing 154. (535 aa)
	FGFR3	Fibroblast growth factor receptor. (808 aa)
	ALDH1A2	Retinal dehydrogenase 2 isoform 1; Belongs to the aldehyde dehydrogenase family. (518 aa)
	IFT80	Intraflagellar transport protein 80 homolog isoform a. (777 aa)
	XYLT1	Xylosyltransferase 1. (959 aa)
	RET	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
	PAX2	Paired box 2. (418 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (862 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTS12	ADAMTS7	ENSMMUP00000060924	ENSMMUP00000078833	ADAM metallopeptidase with thrombospondin type 1 motif 12.	ADAM metallopeptidase with thrombospondin type 1 motif 7.	0.450
ADAMTS7	ADAMTS12	ENSMMUP00000078833	ENSMMUP00000060924	ADAM metallopeptidase with thrombospondin type 1 motif 7.	ADAM metallopeptidase with thrombospondin type 1 motif 12.	0.450
BMP2	IGF1	ENSMMUP00000065891	ENSMMUP00000002988	Bone morphogenetic protein 2.	Insulin like growth factor 1.	0.596
FGFR3	IGF1	ENSMMUP00000026225	ENSMMUP00000002988	Fibroblast growth factor receptor.	Insulin like growth factor 1.	0.753
GATA3	ZBTB16	ENSMMUP00000009115	ENSMMUP00000009286	GATA binding protein 3.	Uncharacterized protein.	0.486
IGF1	BMP2	ENSMMUP00000002988	ENSMMUP00000065891	Insulin like growth factor 1.	Bone morphogenetic protein 2.	0.596
IGF1	FGFR3	ENSMMUP00000002988	ENSMMUP00000026225	Insulin like growth factor 1.	Fibroblast growth factor receptor.	0.753
PLXNB1	RHOA	ENSMMUP00000049193	ENSMMUP00000045801	Plexin B1.	Ras homolog family member A.	0.669
PLXNB1	SEMA4D	ENSMMUP00000049193	ENSMMUP00000011320	Plexin B1.	Semaphorin 4D; Belongs to the semaphorin family.	0.999
RET	ZBTB16	ENSMMUP00000020196	ENSMMUP00000009286	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	Uncharacterized protein.	0.488
RHOA	PLXNB1	ENSMMUP00000045801	ENSMMUP00000049193	Ras homolog family member A.	Plexin B1.	0.669
RHOA	SEMA4D	ENSMMUP00000045801	ENSMMUP00000011320	Ras homolog family member A.	Semaphorin 4D; Belongs to the semaphorin family.	0.699
SEMA4D	PLXNB1	ENSMMUP00000011320	ENSMMUP00000049193	Semaphorin 4D; Belongs to the semaphorin family.	Plexin B1.	0.999
SEMA4D	RHOA	ENSMMUP00000011320	ENSMMUP00000045801	Semaphorin 4D; Belongs to the semaphorin family.	Ras homolog family member A.	0.699
ZBTB16	GATA3	ENSMMUP00000009286	ENSMMUP00000009115	Uncharacterized protein.	GATA binding protein 3.	0.486
ZBTB16	RET	ENSMMUP00000009286	ENSMMUP00000020196	Uncharacterized protein.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.488