STRINGSTRING
CHRNA10 CHRNA10 FGF20 FGF20 TBX3 TBX3 NAGLU NAGLU TMIE TMIE HMX2 HMX2 BMP4 BMP4 SIX1 SIX1 ITGA8 ITGA8 MAF MAF C1QB C1QB LOC703641 LOC703641 LHFPL5 LHFPL5 ADAM10 ADAM10 USH1G USH1G JAG2 JAG2 DLX5 DLX5 WNT5A WNT5A FRZB FRZB MYO3B MYO3B SOX9 SOX9 LOC721827 LOC721827 C1QTNF5 C1QTNF5 SDC4 SDC4 IFT27 IFT27 LOC114676724 LOC114676724 ATP8A2 ATP8A2 ENSMMUP00000069148 ENSMMUP00000069148 TIFAB TIFAB PROX1 PROX1 PVALB PVALB SPRY2 SPRY2 NTN1 NTN1 GLI3 GLI3 GJB6 GJB6 PHOX2B PHOX2B OTX1 OTX1 PJVK PJVK SOD1 SOD1 BMP2 BMP2 FZD3 FZD3 CDKN1B CDKN1B SHH SHH PLS1 PLS1 TGFB2 TGFB2 GRXCR2 GRXCR2 HPCA HPCA HEY2 HEY2 IFT88 IFT88 KCNK3 KCNK3 HES5 HES5 TSKU TSKU DVL2 DVL2 PRRX1 PRRX1 LGR5 LGR5 LRTOMT LRTOMT TTC39C TTC39C HESX1 HESX1 LRRC1 LRRC1 FGF10 FGF10 TFAP2A TFAP2A EYA1 EYA1 ATG4B ATG4B TBX1 TBX1 TBX2 TBX2 ATP8B1 ATP8B1 PTPN11 PTPN11 EPHB2 EPHB2 DLX6 DLX6 EPHA4 EPHA4 FGFR2 FGFR2 SCRIB SCRIB DVL1 DVL1 CCM2 CCM2 WDPCP WDPCP MYO3A MYO3A TRIOBP TRIOBP SLC26A5 SLC26A5 PTPRQ PTPRQ MYO15A MYO15A LHX3 LHX3 WHRN WHRN LRIG1 LRIG1 LRIG3 LRIG3 GATA2 GATA2 CYS1 CYS1 HPCAL1 HPCAL1 ZEB1 ZEB1 STOX1 STOX1 CHRNA9 CHRNA9 GRXCR1 GRXCR1 GSDME GSDME PTK7 PTK7 FZD6 FZD6 HPN HPN TGFB1 TGFB1 USH1C USH1C MAPKAPK2 MAPKAPK2 GABRA5 GABRA5 SEC24B SEC24B SOBP SOBP USH2A USH2A PDZD7 PDZD7 STRC STRC SLC44A4 SLC44A4 CLRN1 CLRN1 FOXG1 FOXG1 DLL1 DLL1 PLPPR4 PLPPR4 RPGRIP1L RPGRIP1L TSHR TSHR ATG5 ATG5 KCNQ4 KCNQ4 CTHRC1 CTHRC1 SLC4A7 SLC4A7 IFT20 IFT20 ADGRV1 ADGRV1 TRIP11 TRIP11 MYO7A MYO7A JAG1 JAG1 GABRB2 GABRB2 SLC17A8 SLC17A8 BMPER BMPER NOTCH1 NOTCH1 REST REST KCNK2 KCNK2 CYTL1 CYTL1 ESRRB ESRRB SLITRK6 SLITRK6 OTOL1 OTOL1 LRP10 LRP10 CEP290 CEP290 FGF8 FGF8 WNT1 WNT1 FOXI1 FOXI1 HOXA13 HOXA13 MYO15B MYO15B CEBPD CEBPD CDH23 CDH23 HOXA1 HOXA1 TMC1 TMC1 ANP32B ANP32B TGFB3 TGFB3 MKS1 MKS1 LIN7A LIN7A CHD7 CHD7 PDGFRB PDGFRB COL2A1 COL2A1 FZD2 FZD2 TBX18 TBX18 MPV17 MPV17 INSIG1 INSIG1 FGF9 FGF9 CCNA2 CCNA2 PCDH15 PCDH15 BCR BCR AHI1 AHI1 PAX2 PAX2 NOX3 NOX3 DUOX2 DUOX2 NEUROD1 NEUROD1 DCHS1 DCHS1 KCNQ1 KCNQ1 GATA3 GATA3 CECR2 CECR2 ALDH1A3 ALDH1A3 GBX2 GBX2 EYA4 EYA4 CLRN2 CLRN2 MCOLN3 MCOLN3 MYO6 MYO6 PDGFA PDGFA WNT3A WNT3A CXCL14 CXCL14 NEUROG1 NEUROG1 ZIC1 ZIC1 ROR1 ROR1 TTC8 TTC8 GRHL3 GRHL3 COL11A1 COL11A1 HMX3 HMX3 OTOP1 OTOP1 FREM2 FREM2 ATOH1 ATOH1 ATP6V1B1 ATP6V1B1 TPRN TPRN SIX4 SIX4 MCM2 MCM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
TBX3T-box transcription factor 3. (743 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
TMIETransmembrane inner ear. (282 aa)
HMX2Homeobox domain-containing protein. (273 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SIX1SIX homeobox 1. (284 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (403 aa)
C1QBComplement C1q subcomponent subunit B. (253 aa)
LOC703641CTCK domain-containing protein. (408 aa)
LHFPL5Uncharacterized protein. (219 aa)
ADAM10ADAM metallopeptidase domain 10. (783 aa)
USH1GUSH1 protein network component sans. (461 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1290 aa)
DLX5Distal-less homeobox 5. (289 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (462 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1358 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
LOC721827Uncharacterized protein; Belongs to the parvalbumin family. (109 aa)
C1QTNF5C1q and TNF related 5. (392 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
IFT27Intraflagellar transport 27. (243 aa)
LOC114676724Uncharacterized protein; Belongs to the parvalbumin family. (109 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1291 aa)
ENSMMUP00000069148Uncharacterized protein. (507 aa)
TIFABTIFA inhibitor. (204 aa)
PROX1Prospero homeobox protein 1. (737 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (178 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
NTN1Netrin 1. (604 aa)
GLI3GLI family zinc finger 3. (1580 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
OTX1Orthodenticle homeobox 1. (354 aa)
PJVKPejvakin. (352 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (161 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
PLS1Plastin 1. (629 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GRXCR2Glutaredoxin and cysteine rich domain containing 2. (184 aa)
HPCANeuron-specific calcium-binding protein hippocalcin. (193 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
IFT88Intraflagellar transport 88. (971 aa)
KCNK3Potassium channel subfamily K member. (394 aa)
HES5Uncharacterized protein. (166 aa)
TSKUUncharacterized protein. (353 aa)
DVL2Dishevelled segment polarity protein 2. (767 aa)
PRRX1Uncharacterized protein. (245 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
LRTOMTTransmembrane O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function (By similarity). Component of the cochlear hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity (By similarity). (295 aa)
TTC39CTetratricopeptide repeat domain 39C. (886 aa)
HESX1HESX homeobox 1. (185 aa)
LRRC1Leucine-rich repeat-containing protein 1. (524 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TFAP2ATranscription factor AP-2 alpha. (445 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (539 aa)
TBX1T-box transcription factor 1. (496 aa)
TBX2T-box transcription factor 2. (712 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
EPHB2EPH receptor B2. (1082 aa)
DLX6Distal-less homeobox 6. (292 aa)
EPHA4EPH receptor A4. (1008 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
SCRIBScribble planar cell polarity protein. (1451 aa)
DVL1Dishevelled segment polarity protein 1. (695 aa)
CCM2PID domain-containing protein. (485 aa)
WDPCPWD repeat containing planar cell polarity effector. (708 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1614 aa)
TRIOBPTRIO and F-actin binding protein. (2288 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (744 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2299 aa)
MYO15AMyosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3528 aa)
LHX3LIM homeobox 3. (402 aa)
WHRNWhirlin. (907 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1088 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1119 aa)
GATA2GATA binding protein 2. (480 aa)
CYS1Cystin 1. (157 aa)
HPCAL1Hippocalcin like 1. (238 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1126 aa)
STOX1Storkhead box 1. (1119 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
GRXCR1Glutaredoxin domain-containing cysteine-rich protein 1. (290 aa)
GSDMEGasdermin E. (495 aa)
PTK7Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
HPNHepsin; Belongs to the peptidase S1 family. (471 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
USH1CUSH1 protein network component harmonin. (899 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (409 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1277 aa)
SOBPJXC1. (874 aa)
USH2AUsherin. (5201 aa)
PDZD7PDZ domain containing 7. (560 aa)
STRCStereocilin. (1768 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (710 aa)
CLRN1Clarin 1. (245 aa)
FOXG1Forkhead box G1. (489 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
PLPPR4Phospholipid phosphatase related 4. (763 aa)
RPGRIP1LC2 domain-containing protein. (1273 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (317 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (695 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
SLC4A7Anion exchange protein. (1242 aa)
IFT20Intraflagellar transport protein 20-like protein. (158 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6306 aa)
TRIP11Thyroid hormone receptor interactor 11. (1819 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2215 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
GABRB2Gamma-aminobutyric acid receptor subunit beta-2; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present [...] (512 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
BMPERBMP binding endothelial regulator. (685 aa)
NOTCH1Notch receptor 1. (2556 aa)
RESTRE1 silencing transcription factor. (1095 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
CYTL1Cytokine-like protein 1. (136 aa)
ESRRBEstrogen related receptor beta. (438 aa)
SLITRK6SLIT and NTRK like family member 6. (841 aa)
OTOL1Otolin 1. (470 aa)
LRP10Low-density lipoprotein receptor-related protein 10. (714 aa)
CEP290Centrosomal protein 290. (2480 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FOXI1Forkhead box I1. (378 aa)
HOXA13Homeobox A13. (226 aa)
MYO15BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1533 aa)
CEBPDCCAAT/enhancer-binding protein. (269 aa)
CDH23Cadherin related 23. (3354 aa)
HOXA1Homeobox protein Hox-1F. (335 aa)
TMC1Transmembrane channel-like protein. (760 aa)
ANP32BLRRcap domain-containing protein. (406 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2998 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
TBX18T-box transcription factor 18. (556 aa)
MPV17Protein Mpv17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (176 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CCNA2Cyclin-A2; Belongs to the cyclin family. (432 aa)
PCDH15Protocadherin related 15. (1960 aa)
BCRBCR activator of RhoGEF and GTPase. (1271 aa)
AHI1Abelson helper integration site 1. (1196 aa)
PAX2Paired box 2. (418 aa)
NOX3NADPH oxidase 3. (568 aa)
DUOX2Dual oxidase 2. (1546 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
DCHS1Dachsous cadherin-related 1. (3221 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
GATA3GATA binding protein 3. (444 aa)
CECR2CECR2 histone acetyl-lysine reader. (1463 aa)
ALDH1A3Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (648 aa)
CLRN2Clarin 2. (232 aa)
MCOLN3Mucolipin 3. (553 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1285 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (249 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CXCL14C-X-C motif chemokine ligand 14. (119 aa)
NEUROG1Neurogenin 1. (237 aa)
ZIC1Zic family member 1. (447 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
GRHL3Grainyhead like transcription factor 3. (626 aa)
COL11A1Collagen alpha-1(XI) chain isoform A preproprotein. (1806 aa)
HMX3H6 family homeobox 3. (357 aa)
OTOP1Otopetrin 1. (610 aa)
FREM2FRAS1 related extracellular matrix 2. (3170 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
TPRNTaperin. (712 aa)
SIX4SIX homeobox 4. (772 aa)
MCM2DNA helicase; Belongs to the MCM family. (904 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (36%) [HD]