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EREG | Proepiregulin. (169 aa) | ||||
CCND2 | Uncharacterized protein. (353 aa) | ||||
MEAF6 | MYST/Esa1 associated factor 6. (203 aa) | ||||
ACTR2 | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa) | ||||
SSBP1 | Uncharacterized protein. (163 aa) | ||||
NABP2 | Sensor of single-strand DNA complex subunit B1. (211 aa) | ||||
SMOC2 | SPARC related modular calcium binding 2. (471 aa) | ||||
RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (497 aa) | ||||
ENSMMUP00000068718 | Reverse transcriptase domain-containing protein. (1075 aa) | ||||
EPC1 | Enhancer of polycomb homolog. (836 aa) | ||||
BCL7B | Uncharacterized protein. (251 aa) | ||||
ENSMMUP00000079633 | FAM35_C domain-containing protein. (120 aa) | ||||
ENSMMUP00000068036 | Uncharacterized protein. (134 aa) | ||||
FMN2 | Formin 2. (1833 aa) | ||||
PPP1R10 | Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] (940 aa) | ||||
HDGFL2 | LEDGF domain-containing protein. (680 aa) | ||||
ENSMMUP00000067093 | Reverse transcriptase domain-containing protein. (873 aa) | ||||
CCDC117 | Coiled-coil domain containing 117. (279 aa) | ||||
ENSMMUP00000066721 | Reverse transcriptase domain-containing protein. (1160 aa) | ||||
ATF1 | Cyclic AMP-dependent transcription factor ATF-1. (270 aa) | ||||
SHLD3 | Shieldin complex subunit 3. (250 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (265 aa) | ||||
ENSMMUP00000066266 | Uncharacterized protein. (188 aa) | ||||
MFSD11 | Major facilitator superfamily domain containing 11. (449 aa) | ||||
BABAM1 | BRISC and BRCA1-A complex member 1. (329 aa) | ||||
GINS1 | GINS complex subunit 1. (456 aa) | ||||
PARM1 | Prostate androgen-regulated mucin-like protein 1. (310 aa) | ||||
CD28 | T-cell-specific surface glycoprotein CD28. (220 aa) | ||||
ENSMMUP00000064847 | Reverse transcriptase domain-containing protein. (860 aa) | ||||
CEBPG | CCAAT/enhancer-binding protein gamma. (150 aa) | ||||
CDC7 | Cell division cycle 7-related protein kinase. (574 aa) | ||||
ENSMMUP00000064422 | Reverse transcriptase domain-containing protein. (860 aa) | ||||
DTX3L | Deltex E3 ubiquitin ligase 3L. (740 aa) | ||||
ENSMMUP00000063857 | DUF1725 domain-containing protein. (120 aa) | ||||
PIAS4 | Protein inhibitor of activated STAT 4. (561 aa) | ||||
PKIB | cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (109 aa) | ||||
ENSMMUP00000063480 | Reverse transcriptase domain-containing protein. (765 aa) | ||||
RIF1 | Replication timing regulatory factor 1. (2466 aa) | ||||
BAZ1A | Bromodomain adjacent to zinc finger domain protein 1A isoform a. (1556 aa) | ||||
KMT5C | Lysine methyltransferase 5C. (461 aa) | ||||
CCT4 | T-complex protein 1 subunit delta. (737 aa) | ||||
VPS72 | Vacuolar protein sorting-associated protein 72 homolog. (364 aa) | ||||
HMCES | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (360 aa) | ||||
CTNNB1 | Catenin beta-1. (781 aa) | ||||
TBX21 | T-box transcription factor 21. (539 aa) | ||||
DNA2 | DNA replication helicase/nuclease 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (1316 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
ENSMMUP00000062445 | Reverse transcriptase domain-containing protein. (1070 aa) | ||||
ENSMMUP00000061990 | Uncharacterized protein. (876 aa) | ||||
ENSMMUP00000061983 | Uncharacterized protein. (134 aa) | ||||
STAT6 | Signal transducer and activator of transcription. (902 aa) | ||||
MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1846 aa) | ||||
SMCHD1 | Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (2005 aa) | ||||
STPG4 | Sperm-tail PG-rich repeat containing 4. (246 aa) | ||||
KCTD13 | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1. (329 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
SPIDR | Scaffold protein involved in DNA repair. (946 aa) | ||||
CCT8 | Uncharacterized protein. (553 aa) | ||||
MRNIP | MRN complex interacting protein. (346 aa) | ||||
PPARGC1A | PPARG coactivator 1 alpha. (818 aa) | ||||
SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1244 aa) | ||||
UCN | Urocortin. (124 aa) | ||||
BRPF3 | Bromodomain and PHD finger containing 3. (1089 aa) | ||||
ENSMMUP00000058534 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa) | ||||
GLI2 | GLI family zinc finger 2. (1569 aa) | ||||
PARP9 | Poly(ADP-ribose) polymerase family member 9. (818 aa) | ||||
NEDD8 | TERF1 interacting nuclear factor 2. (482 aa) | ||||
MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa) | ||||
FAM178B | Family with sequence similarity 178 member B. (679 aa) | ||||
NFRKB | Nuclear factor related to kappaB binding protein. (1433 aa) | ||||
WAS | WASP actin nucleation promoting factor. (503 aa) | ||||
NSD2 | Uncharacterized protein. (1362 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) | ||||
DPF3 | Double PHD fingers 3. (410 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
ACTB | Uncharacterized protein. (421 aa) | ||||
TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3873 aa) | ||||
MBTD1 | Mbt domain containing 1. (754 aa) | ||||
SPIRE1 | Spire type actin nucleation factor 1. (815 aa) | ||||
EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa) | ||||
UBE2N | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa) | ||||
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (442 aa) | ||||
NEK2 | Serine/threonine-protein kinase Nek2 isoform 1. (445 aa) | ||||
KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa) | ||||
YEATS4 | YEATS domain-containing protein 4. (227 aa) | ||||
TNFSF4 | Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (183 aa) | ||||
ATAD5 | ATPase family AAA domain containing 5. (1848 aa) | ||||
UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (472 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (266 aa) | ||||
SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (470 aa) | ||||
OTUD4 | OTU deubiquitinase 4. (1113 aa) | ||||
RBBP8 | Uncharacterized protein. (898 aa) | ||||
ERCC2 | TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa) | ||||
ABRAXAS1 | BRCA1-A complex subunit Abraxas. (409 aa) | ||||
MMS19 | MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa) | ||||
EGFR | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa) | ||||
BRCC3 | BRCA1/BRCA2-containing complex subunit 3. (291 aa) | ||||
MRGBP | MRG domain binding protein. (204 aa) | ||||
MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa) | ||||
APLF | Aprataxin and PNKP like factor. (512 aa) | ||||
WDR48 | WD repeat domain 48. (745 aa) | ||||
CCT5 | T-complex protein 1 subunit epsilon. (541 aa) | ||||
ACTG1 | Actin, cytoplasmic 2. (375 aa) | ||||
SLF2 | Uncharacterized protein. (1187 aa) | ||||
PAXIP1 | PAX interacting protein 1. (1154 aa) | ||||
EXOSC3 | Exosome complex component RRP40 isoform 1. (275 aa) | ||||
MAD2L2 | Mitotic arrest deficient 2 like 2. (212 aa) | ||||
DMAP1 | DNA methyltransferase 1 associated protein 1. (612 aa) | ||||
DDX11 | DEAD/H-box helicase 11. (970 aa) | ||||
CCT2 | Chaperonin containing TCP1 subunit 2. (589 aa) | ||||
RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) | ||||
CCT3 | T-complex protein 1 subunit gamma. (545 aa) | ||||
EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (538 aa) | ||||
RPS3 | 40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) | ||||
MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (933 aa) | ||||
SIRT1 | Sirtuin 1. (743 aa) | ||||
ZCWPW1 | Zinc finger CW-type and PWWP domain containing 1. (649 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1884 aa) | ||||
RAD51 | RAD51 recombinase; Belongs to the RecA family. (380 aa) | ||||
F6VHV6_MACMU | Reverse transcriptase domain-containing protein. (863 aa) | ||||
UIMC1 | Ubiquitin interaction motif containing 1. (719 aa) | ||||
SPIRE2 | Spire type actin nucleation factor 2. (714 aa) | ||||
WIZ | WIZ zinc finger. (968 aa) | ||||
PNKP | Polynucleotide kinase 3'-phosphatase. (532 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
EPC2 | Enhancer of polycomb homolog. (783 aa) | ||||
E2F7 | E2F transcription factor 7. (910 aa) | ||||
WRN | WRN RecQ like helicase. (1426 aa) | ||||
ATRX | ATRX chromatin remodeler. (2490 aa) | ||||
MLH1 | MutL homolog 1. (756 aa) | ||||
NVL | Nuclear VCP like. (856 aa) | ||||
TFPT | TCF3 fusion partner. (253 aa) | ||||
ANXA3 | Annexin. (328 aa) | ||||
PARP3 | Poly [ADP-ribose] polymerase. (532 aa) | ||||
GLI1 | Zinc finger protein GLI1 isoform 1. (1106 aa) | ||||
TIMELESS | Timeless circadian regulator. (1204 aa) | ||||
PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) | ||||
ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (375 aa) | ||||
NEK7 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (381 aa) | ||||
IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa) | ||||
GRHL2 | Grainyhead like transcription factor 2. (625 aa) | ||||
POGZ | Pogo transposable element derived with ZNF domain. (1492 aa) | ||||
PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (739 aa) | ||||
GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) | ||||
POT1 | Protection of telomeres 1. (658 aa) | ||||
INO80E | Uncharacterized protein. (243 aa) | ||||
SRC | Tyrosine-protein kinase. (644 aa) | ||||
TRIM28 | Tripartite motif containing 28. (834 aa) | ||||
SIRT6 | NAD-dependent deacetylase sirtuin-6. (355 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa) | ||||
FUS | Tripartite motif containing 72. (534 aa) | ||||
FOXM1 | Forkhead box protein M1 isoform 2. (770 aa) | ||||
ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa) | ||||
FAF1 | FAS-associated factor 1. (650 aa) | ||||
HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa) | ||||
TMEM161A | Transmembrane protein 161A. (479 aa) | ||||
ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (2061 aa) | ||||
PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) | ||||
FANCB | FA complementation group B. (858 aa) | ||||
SETMAR | SET domain and mariner transposase fusion gene. (684 aa) | ||||
ENSMMUP00000079943 | Reverse transcriptase domain-containing protein. (887 aa) | ||||
ENSMMUP00000080065 | Uncharacterized protein. (73 aa) | ||||
DKC1 | PUA domain-containing protein. (556 aa) | ||||
ENSMMUP00000072510 | Reverse transcriptase domain-containing protein. (1125 aa) | ||||
ENSMMUP00000071941 | Reverse transcriptase domain-containing protein. (1177 aa) | ||||
BABAM2 | BRISC and BRCA1 A complex member 2. (423 aa) | ||||
SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (533 aa) | ||||
INO80 | Putative DNA helicase INO80 complex-like protein 1. (1556 aa) | ||||
ENSMMUP00000070668 | Reverse transcriptase domain-containing protein. (878 aa) | ||||
ING3 | Inhibitor of growth protein. (418 aa) | ||||
ENSMMUP00000073070 | Reverse transcriptase domain-containing protein. (1117 aa) | ||||
MORF4L2 | Mortality factor 4 like 2. (288 aa) | ||||
ENSMMUP00000073151 | zf-H2C2 domain-containing protein. (185 aa) | ||||
MAPKAPK5 | MAP kinase-activated protein kinase 5 isoform 1. (471 aa) | ||||
HNRNPD | Heterogeneous nuclear ribonucleoprotein D0 isoform a. (355 aa) | ||||
ENSMMUP00000074181 | Reverse transcriptase domain-containing protein. (730 aa) | ||||
ENSMMUP00000074362 | Reverse transcriptase domain-containing protein. (809 aa) | ||||
ENSMMUP00000074969 | Endo/exonuclease/phosphatase domain-containing protein. (162 aa) | ||||
ENSMMUP00000075287 | Reverse transcriptase domain-containing protein. (917 aa) | ||||
CCT8L2 | Chaperonin containing TCP1 subunit 8 like 2. (557 aa) | ||||
E2F8 | E2F transcription factor 8. (867 aa) | ||||
PRKCD | Protein kinase C. (729 aa) | ||||
KLF4 | Kruppel like factor 4. (544 aa) | ||||
APOBEC1 | Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (236 aa) | ||||
ENSMMUP00000077180 | Reverse transcriptase domain-containing protein. (882 aa) | ||||
STOML2 | Stomatin-like protein 2. (356 aa) | ||||
KMT5B | Histone-lysine N-methyltransferase SUV420H1 isoform 1. (885 aa) | ||||
GFER | Sulfhydryl oxidase. (205 aa) | ||||
SHLD1 | Shieldin complex subunit 1. (228 aa) | ||||
ENSMMUP00000078409 | Reverse transcriptase domain-containing protein. (850 aa) | ||||
LOC114669758 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (440 aa) | ||||
LPIN1 | Lipin 1. (975 aa) | ||||
ENSMMUP00000078516 | Endo/exonuclease/phosphatase domain-containing protein. (185 aa) | ||||
ENSMMUP00000078666 | Uncharacterized protein. (93 aa) | ||||
EP400 | E1A binding protein p400. (3045 aa) | ||||
PBRM1 | Polybromo 1. (1655 aa) | ||||
NRM | Nurim. (262 aa) | ||||
TP53BP1 | Tumor protein p53 binding protein 1. (1977 aa) | ||||
TERF2 | Telomeric repeat binding factor 2. (542 aa) | ||||
MAS1 | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa) | ||||
ARID2 | AT-rich interaction domain 2. (1836 aa) | ||||
BCAR3 | BCAR3 adaptor protein, NSP family member. (835 aa) | ||||
PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa) | ||||
HELQ | Helicase, POLQ like. (1101 aa) | ||||
PHF10 | PHD finger protein 10. (563 aa) | ||||
SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1586 aa) | ||||
CCT6A | T-complex protein 1 subunit zeta isoform a. (531 aa) | ||||
RAD51AP1 | RAD51 associated protein 1. (352 aa) | ||||
HMBOX1 | Homeobox-containing protein 1. (420 aa) | ||||
HSF1 | Heat shock transcription factor 1. (507 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (471 aa) | ||||
HDAC10 | Histone deacetylase 10. (939 aa) | ||||
CYP1B1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (542 aa) | ||||
CDT1 | Chromatin licensing and DNA replication factor 1. (551 aa) | ||||
CIZ1 | CDKN1A interacting zinc finger protein 1. (906 aa) | ||||
SHLD2 | FAM35_C domain-containing protein. (881 aa) | ||||
EYA3 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (579 aa) | ||||
ARID1A | AT-rich interaction domain 1A. (2287 aa) | ||||
BCL7A | B-cell CLL/lymphoma 7 protein family member A isoform a. (231 aa) | ||||
SYNCRIP | Synaptotagmin binding cytoplasmic RNA interacting protein. (608 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) | ||||
GNL3 | Guanine nucleotide-binding protein-like 3 isoform 1. (549 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1367 aa) | ||||
UBE2V2 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) | ||||
SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa) | ||||
RGCC | Uncharacterized protein. (162 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) | ||||
MGMT | Methylated-DNA--protein-cysteine methyltransferase. (238 aa) | ||||
DHX36 | DEAH-box helicase 36. (1008 aa) | ||||
MCRS1 | Microspherule protein 1. (475 aa) | ||||
TOX | Thymocyte selection associated high mobility group box. (526 aa) | ||||
DERPC | DERPC proline and glycine rich nuclear protein. (522 aa) | ||||
RFC5 | Replication factor C subunit 5 isoform 1. (340 aa) | ||||
KHDC3L | KH domain containing 3 like, subcortical maternal complex member. (206 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1213 aa) | ||||
WT1 | WT1 transcription factor. (517 aa) | ||||
NPAS2 | Neuronal PAS domain-containing protein 2. (824 aa) | ||||
ACD | ACD shelterin complex subunit and telomerase recruitment factor. (455 aa) | ||||
ACTL6A | Actin-like protein 6A isoform 1; Belongs to the actin family. (429 aa) | ||||
POLG2 | DNA polymerase gamma 2, accessory subunit. (485 aa) | ||||
LOC705671 | Uncharacterized protein. (398 aa) | ||||
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1132 aa) | ||||
GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) | ||||
GINS3 | GINS complex subunit 3. (255 aa) | ||||
SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) | ||||
WRAP53 | Telomerase Cajal body protein 1. (548 aa) | ||||
ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) | ||||
SLX4 | SLX4 structure-specific endonuclease subunit. (1668 aa) | ||||
TNKS2 | Poly [ADP-ribose] polymerase. (1258 aa) | ||||
ACTL6B | Actin like 6B; Belongs to the actin family. (449 aa) | ||||
SLX1A | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (437 aa) | ||||
DBF4 | Protein DBF4 homolog A. (675 aa) | ||||
SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (603 aa) | ||||
EYA4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (648 aa) | ||||
FH | Fumarate hydratase, mitochondrial. (510 aa) | ||||
DHX9 | ATP-dependent RNA helicase A. (1275 aa) | ||||
FGFR4 | Fibroblast growth factor receptor. (859 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) | ||||
USP7 | Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1102 aa) | ||||
RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (661 aa) | ||||
SMARCE1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1. (411 aa) | ||||
HNRNPAB | Heterogeneous nuclear ribonucleoprotein A/B isoform a. (332 aa) | ||||
FBXO4 | F-box protein 4. (490 aa) | ||||
BAX | Uncharacterized protein. (279 aa) | ||||
RFC2 | Replication factor C subunit 2. (233 aa) | ||||
PRDM9 | Uncharacterized protein. (482 aa) | ||||
RFC4 | Replication factor C subunit 4. (363 aa) | ||||
CD40 | Tumor necrosis factor receptor superfamily member 5 isoform 1. (278 aa) | ||||
DPF1 | Zinc finger protein neuro-d4 isoform a. (414 aa) | ||||
RFC3 | Replication factor C subunit 3 isoform 1. (356 aa) | ||||
BCL7C | Uncharacterized protein. (242 aa) | ||||
FAM168A | Uncharacterized protein. (244 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (153 aa) | ||||
AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (345 aa) | ||||
DSCC1 | DNA replication and sister chromatid cohesion 1. (393 aa) | ||||
INO80B | INO80 complex subunit B. (356 aa) | ||||
PML | Promyelocytic leukemia protein. (882 aa) | ||||
ARID1B | AT-rich interaction domain 1B. (2428 aa) | ||||
TFRC | Transferrin receptor protein 1. (760 aa) | ||||
CTC1 | CST telomere replication complex component 1. (1267 aa) | ||||
XRCC5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa) | ||||
NAF1 | Nuclear assembly factor 1 ribonucleoprotein. (497 aa) | ||||
BRD8 | Bromodomain containing 8. (1235 aa) | ||||
SLF1 | SMC5-SMC6 complex localization factor 1. (1059 aa) | ||||
MAPK15 | Mitogen-activated protein kinase. (544 aa) | ||||
PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa) | ||||
INO80D | INO80 complex subunit D. (1027 aa) | ||||
TNKS | Poly [ADP-ribose] polymerase. (1327 aa) | ||||
CHTF18 | Chromosome transmission fidelity factor 18. (975 aa) | ||||
DBF4B | DBF4 zinc finger B. (684 aa) | ||||
SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa) | ||||
OOEP | Oocyte expressed protein. (149 aa) |