STRINGSTRING
EREG EREG CCND2 CCND2 MEAF6 MEAF6 ACTR2 ACTR2 SSBP1 SSBP1 NABP2 NABP2 SMOC2 SMOC2 RUVBL2 RUVBL2 ENSMMUP00000068718 ENSMMUP00000068718 EPC1 EPC1 BCL7B BCL7B ENSMMUP00000079633 ENSMMUP00000079633 ENSMMUP00000068036 ENSMMUP00000068036 FMN2 FMN2 PPP1R10 PPP1R10 HDGFL2 HDGFL2 ENSMMUP00000067093 ENSMMUP00000067093 CCDC117 CCDC117 ENSMMUP00000066721 ENSMMUP00000066721 ATF1 ATF1 SHLD3 SHLD3 PDGFB PDGFB ENSMMUP00000066266 ENSMMUP00000066266 MFSD11 MFSD11 BABAM1 BABAM1 GINS1 GINS1 PARM1 PARM1 CD28 CD28 ENSMMUP00000064847 ENSMMUP00000064847 CEBPG CEBPG CDC7 CDC7 ENSMMUP00000064422 ENSMMUP00000064422 DTX3L DTX3L ENSMMUP00000063857 ENSMMUP00000063857 PIAS4 PIAS4 PKIB PKIB ENSMMUP00000063480 ENSMMUP00000063480 RIF1 RIF1 BAZ1A BAZ1A KMT5C KMT5C CCT4 CCT4 VPS72 VPS72 HMCES HMCES CTNNB1 CTNNB1 TBX21 TBX21 DNA2 DNA2 PCNA PCNA ENSMMUP00000062445 ENSMMUP00000062445 ENSMMUP00000061990 ENSMMUP00000061990 ENSMMUP00000061983 ENSMMUP00000061983 STAT6 STAT6 MAP3K4 MAP3K4 SMCHD1 SMCHD1 STPG4 STPG4 KCTD13 KCTD13 AKT1 AKT1 SPIDR SPIDR CCT8 CCT8 MRNIP MRNIP PPARGC1A PPARGC1A SMARCC2 SMARCC2 UCN UCN BRPF3 BRPF3 ENSMMUP00000058534 ENSMMUP00000058534 GLI2 GLI2 PARP9 PARP9 NEDD8 NEDD8 MECP2 MECP2 FAM178B FAM178B NFRKB NFRKB WAS WAS NSD2 NSD2 PTPRC PTPRC DPF3 DPF3 FGF10 FGF10 MAPK3 MAPK3 ACTB ACTB TRRAP TRRAP MBTD1 MBTD1 SPIRE1 SPIRE1 EYA1 EYA1 UBE2N UBE2N ERCC1 ERCC1 NEK2 NEK2 KAT7 KAT7 YEATS4 YEATS4 TNFSF4 TNFSF4 ATAD5 ATAD5 UCHL5 UCHL5 IL6 IL6 SMARCD2 SMARCD2 OTUD4 OTUD4 RBBP8 RBBP8 ERCC2 ERCC2 ABRAXAS1 ABRAXAS1 MMS19 MMS19 EGFR EGFR BRCC3 BRCC3 MRGBP MRGBP MAP2K4 MAP2K4 APLF APLF WDR48 WDR48 CCT5 CCT5 ACTG1 ACTG1 SLF2 SLF2 PAXIP1 PAXIP1 EXOSC3 EXOSC3 MAD2L2 MAD2L2 DMAP1 DMAP1 DDX11 DDX11 CCT2 CCT2 RUVBL1 RUVBL1 CCT3 CCT3 EYA2 EYA2 RPS3 RPS3 MSH2 MSH2 SIRT1 SIRT1 ZCWPW1 ZCWPW1 BRCA1 BRCA1 RAD51 RAD51 F6VHV6_MACMU F6VHV6_MACMU UIMC1 UIMC1 SPIRE2 SPIRE2 WIZ WIZ PNKP PNKP PRKCG PRKCG TGFB1 TGFB1 EPC2 EPC2 E2F7 E2F7 WRN WRN ATRX ATRX MLH1 MLH1 NVL NVL TFPT TFPT ANXA3 ANXA3 PARP3 PARP3 GLI1 GLI1 TIMELESS TIMELESS PARP1 PARP1 ERCC8 ERCC8 NEK7 NEK7 IL2 IL2 GRHL2 GRHL2 POGZ POGZ PRKCQ PRKCQ GINS2 GINS2 POT1 POT1 INO80E INO80E SRC SRC TRIM28 TRIM28 SIRT6 SIRT6 KAT5 KAT5 FUS FUS FOXM1 FOXM1 ACTR8 ACTR8 PTK2B PTK2B FAF1 FAF1 HGF HGF TMEM161A TMEM161A ERCC6 ERCC6 PRKD2 PRKD2 FANCB FANCB SETMAR SETMAR ENSMMUP00000079943 ENSMMUP00000079943 ENSMMUP00000080065 ENSMMUP00000080065 DKC1 DKC1 ENSMMUP00000072510 ENSMMUP00000072510 ENSMMUP00000071941 ENSMMUP00000071941 BABAM2 BABAM2 SMARCD3 SMARCD3 INO80 INO80 ENSMMUP00000070668 ENSMMUP00000070668 ING3 ING3 ENSMMUP00000073070 ENSMMUP00000073070 MORF4L2 MORF4L2 ENSMMUP00000073151 ENSMMUP00000073151 MAPKAPK5 MAPKAPK5 HNRNPD HNRNPD ENSMMUP00000074181 ENSMMUP00000074181 ENSMMUP00000074362 ENSMMUP00000074362 ENSMMUP00000074969 ENSMMUP00000074969 ENSMMUP00000075287 ENSMMUP00000075287 CCT8L2 CCT8L2 E2F8 E2F8 PRKCD PRKCD KLF4 KLF4 APOBEC1 APOBEC1 ENSMMUP00000077180 ENSMMUP00000077180 STOML2 STOML2 KMT5B KMT5B GFER GFER SHLD1 SHLD1 ENSMMUP00000078409 ENSMMUP00000078409 LOC114669758 LOC114669758 LPIN1 LPIN1 ENSMMUP00000078516 ENSMMUP00000078516 ENSMMUP00000078666 ENSMMUP00000078666 EP400 EP400 PBRM1 PBRM1 NRM NRM TP53BP1 TP53BP1 TERF2 TERF2 MAS1 MAS1 ARID2 ARID2 BCAR3 BCAR3 PRKDC PRKDC HELQ HELQ PHF10 PHF10 SMARCA2 SMARCA2 CCT6A CCT6A RAD51AP1 RAD51AP1 HMBOX1 HMBOX1 HSF1 HSF1 MYC MYC HDAC10 HDAC10 CYP1B1 CYP1B1 CDT1 CDT1 CIZ1 CIZ1 SHLD2 SHLD2 EYA3 EYA3 ARID1A ARID1A BCL7A BCL7A SYNCRIP SYNCRIP MAPK1 MAPK1 GNL3 GNL3 IGF1R IGF1R UBE2V2 UBE2V2 SMARCA4 SMARCA4 RGCC RGCC PDGFRB PDGFRB MGMT MGMT DHX36 DHX36 MCRS1 MCRS1 TOX TOX DERPC DERPC RFC5 RFC5 KHDC3L KHDC3L EGF EGF WT1 WT1 NPAS2 NPAS2 ACD ACD ACTL6A ACTL6A POLG2 POLG2 LOC705671 LOC705671 SMARCC1 SMARCC1 GINS4 GINS4 GINS3 GINS3 SMARCB1 SMARCB1 WRAP53 WRAP53 ATR ATR SLX4 SLX4 TNKS2 TNKS2 ACTL6B ACTL6B SLX1A SLX1A DBF4 DBF4 SMARCD1 SMARCD1 EYA4 EYA4 FH FH DHX9 DHX9 FGFR4 FGFR4 ATM ATM USP7 USP7 RNF168 RNF168 SMARCE1 SMARCE1 HNRNPAB HNRNPAB FBXO4 FBXO4 BAX BAX RFC2 RFC2 PRDM9 PRDM9 RFC4 RFC4 CD40 CD40 DPF1 DPF1 RFC3 RFC3 BCL7C BCL7C FAM168A FAM168A IL4 IL4 AURKB AURKB DSCC1 DSCC1 INO80B INO80B PML PML ARID1B ARID1B TFRC TFRC CTC1 CTC1 XRCC5 XRCC5 NAF1 NAF1 BRD8 BRD8 SLF1 SLF1 MAPK15 MAPK15 PRIM2 PRIM2 INO80D INO80D TNKS TNKS CHTF18 CHTF18 DBF4B DBF4B SMARCA5 SMARCA5 OOEP OOEP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EREGProepiregulin. (169 aa)
CCND2Uncharacterized protein. (353 aa)
MEAF6MYST/Esa1 associated factor 6. (203 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
SSBP1Uncharacterized protein. (163 aa)
NABP2Sensor of single-strand DNA complex subunit B1. (211 aa)
SMOC2SPARC related modular calcium binding 2. (471 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (497 aa)
ENSMMUP00000068718Reverse transcriptase domain-containing protein. (1075 aa)
EPC1Enhancer of polycomb homolog. (836 aa)
BCL7BUncharacterized protein. (251 aa)
ENSMMUP00000079633FAM35_C domain-containing protein. (120 aa)
ENSMMUP00000068036Uncharacterized protein. (134 aa)
FMN2Formin 2. (1833 aa)
PPP1R10Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] (940 aa)
HDGFL2LEDGF domain-containing protein. (680 aa)
ENSMMUP00000067093Reverse transcriptase domain-containing protein. (873 aa)
CCDC117Coiled-coil domain containing 117. (279 aa)
ENSMMUP00000066721Reverse transcriptase domain-containing protein. (1160 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1. (270 aa)
SHLD3Shieldin complex subunit 3. (250 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (265 aa)
ENSMMUP00000066266Uncharacterized protein. (188 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
BABAM1BRISC and BRCA1-A complex member 1. (329 aa)
GINS1GINS complex subunit 1. (456 aa)
PARM1Prostate androgen-regulated mucin-like protein 1. (310 aa)
CD28T-cell-specific surface glycoprotein CD28. (220 aa)
ENSMMUP00000064847Reverse transcriptase domain-containing protein. (860 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (150 aa)
CDC7Cell division cycle 7-related protein kinase. (574 aa)
ENSMMUP00000064422Reverse transcriptase domain-containing protein. (860 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (740 aa)
ENSMMUP00000063857DUF1725 domain-containing protein. (120 aa)
PIAS4Protein inhibitor of activated STAT 4. (561 aa)
PKIBcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (109 aa)
ENSMMUP00000063480Reverse transcriptase domain-containing protein. (765 aa)
RIF1Replication timing regulatory factor 1. (2466 aa)
BAZ1ABromodomain adjacent to zinc finger domain protein 1A isoform a. (1556 aa)
KMT5CLysine methyltransferase 5C. (461 aa)
CCT4T-complex protein 1 subunit delta. (737 aa)
VPS72Vacuolar protein sorting-associated protein 72 homolog. (364 aa)
HMCESAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (360 aa)
CTNNB1Catenin beta-1. (781 aa)
TBX21T-box transcription factor 21. (539 aa)
DNA2DNA replication helicase/nuclease 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (1316 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ENSMMUP00000062445Reverse transcriptase domain-containing protein. (1070 aa)
ENSMMUP00000061990Uncharacterized protein. (876 aa)
ENSMMUP00000061983Uncharacterized protein. (134 aa)
STAT6Signal transducer and activator of transcription. (902 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1846 aa)
SMCHD1Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (2005 aa)
STPG4Sperm-tail PG-rich repeat containing 4. (246 aa)
KCTD13BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1. (329 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
SPIDRScaffold protein involved in DNA repair. (946 aa)
CCT8Uncharacterized protein. (553 aa)
MRNIPMRN complex interacting protein. (346 aa)
PPARGC1APPARG coactivator 1 alpha. (818 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1244 aa)
UCNUrocortin. (124 aa)
BRPF3Bromodomain and PHD finger containing 3. (1089 aa)
ENSMMUP00000058534UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
GLI2GLI family zinc finger 2. (1569 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (818 aa)
NEDD8TERF1 interacting nuclear factor 2. (482 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
FAM178BFamily with sequence similarity 178 member B. (679 aa)
NFRKBNuclear factor related to kappaB binding protein. (1433 aa)
WASWASP actin nucleation promoting factor. (503 aa)
NSD2Uncharacterized protein. (1362 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
DPF3Double PHD fingers 3. (410 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ACTBUncharacterized protein. (421 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3873 aa)
MBTD1Mbt domain containing 1. (754 aa)
SPIRE1Spire type actin nucleation factor 1. (815 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (442 aa)
NEK2Serine/threonine-protein kinase Nek2 isoform 1. (445 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
YEATS4YEATS domain-containing protein 4. (227 aa)
TNFSF4Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (183 aa)
ATAD5ATPase family AAA domain containing 5. (1848 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (472 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (266 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (470 aa)
OTUD4OTU deubiquitinase 4. (1113 aa)
RBBP8Uncharacterized protein. (898 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
ABRAXAS1BRCA1-A complex subunit Abraxas. (409 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
EGFREpidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (291 aa)
MRGBPMRG domain binding protein. (204 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
APLFAprataxin and PNKP like factor. (512 aa)
WDR48WD repeat domain 48. (745 aa)
CCT5T-complex protein 1 subunit epsilon. (541 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
SLF2Uncharacterized protein. (1187 aa)
PAXIP1PAX interacting protein 1. (1154 aa)
EXOSC3Exosome complex component RRP40 isoform 1. (275 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (212 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (612 aa)
DDX11DEAD/H-box helicase 11. (970 aa)
CCT2Chaperonin containing TCP1 subunit 2. (589 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (538 aa)
RPS340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (933 aa)
SIRT1Sirtuin 1. (743 aa)
ZCWPW1Zinc finger CW-type and PWWP domain containing 1. (649 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1884 aa)
RAD51RAD51 recombinase; Belongs to the RecA family. (380 aa)
F6VHV6_MACMUReverse transcriptase domain-containing protein. (863 aa)
UIMC1Ubiquitin interaction motif containing 1. (719 aa)
SPIRE2Spire type actin nucleation factor 2. (714 aa)
WIZWIZ zinc finger. (968 aa)
PNKPPolynucleotide kinase 3'-phosphatase. (532 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
EPC2Enhancer of polycomb homolog. (783 aa)
E2F7E2F transcription factor 7. (910 aa)
WRNWRN RecQ like helicase. (1426 aa)
ATRXATRX chromatin remodeler. (2490 aa)
MLH1MutL homolog 1. (756 aa)
NVLNuclear VCP like. (856 aa)
TFPTTCF3 fusion partner. (253 aa)
ANXA3Annexin. (328 aa)
PARP3Poly [ADP-ribose] polymerase. (532 aa)
GLI1Zinc finger protein GLI1 isoform 1. (1106 aa)
TIMELESSTimeless circadian regulator. (1204 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (375 aa)
NEK7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (381 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
POGZPogo transposable element derived with ZNF domain. (1492 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (739 aa)
GINS2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
POT1Protection of telomeres 1. (658 aa)
INO80EUncharacterized protein. (243 aa)
SRCTyrosine-protein kinase. (644 aa)
TRIM28Tripartite motif containing 28. (834 aa)
SIRT6NAD-dependent deacetylase sirtuin-6. (355 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa)
FUSTripartite motif containing 72. (534 aa)
FOXM1Forkhead box protein M1 isoform 2. (770 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
FAF1FAS-associated factor 1. (650 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa)
TMEM161ATransmembrane protein 161A. (479 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (2061 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
FANCBFA complementation group B. (858 aa)
SETMARSET domain and mariner transposase fusion gene. (684 aa)
ENSMMUP00000079943Reverse transcriptase domain-containing protein. (887 aa)
ENSMMUP00000080065Uncharacterized protein. (73 aa)
DKC1PUA domain-containing protein. (556 aa)
ENSMMUP00000072510Reverse transcriptase domain-containing protein. (1125 aa)
ENSMMUP00000071941Reverse transcriptase domain-containing protein. (1177 aa)
BABAM2BRISC and BRCA1 A complex member 2. (423 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (533 aa)
INO80Putative DNA helicase INO80 complex-like protein 1. (1556 aa)
ENSMMUP00000070668Reverse transcriptase domain-containing protein. (878 aa)
ING3Inhibitor of growth protein. (418 aa)
ENSMMUP00000073070Reverse transcriptase domain-containing protein. (1117 aa)
MORF4L2Mortality factor 4 like 2. (288 aa)
ENSMMUP00000073151zf-H2C2 domain-containing protein. (185 aa)
MAPKAPK5MAP kinase-activated protein kinase 5 isoform 1. (471 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D0 isoform a. (355 aa)
ENSMMUP00000074181Reverse transcriptase domain-containing protein. (730 aa)
ENSMMUP00000074362Reverse transcriptase domain-containing protein. (809 aa)
ENSMMUP00000074969Endo/exonuclease/phosphatase domain-containing protein. (162 aa)
ENSMMUP00000075287Reverse transcriptase domain-containing protein. (917 aa)
CCT8L2Chaperonin containing TCP1 subunit 8 like 2. (557 aa)
E2F8E2F transcription factor 8. (867 aa)
PRKCDProtein kinase C. (729 aa)
KLF4Kruppel like factor 4. (544 aa)
APOBEC1Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (236 aa)
ENSMMUP00000077180Reverse transcriptase domain-containing protein. (882 aa)
STOML2Stomatin-like protein 2. (356 aa)
KMT5BHistone-lysine N-methyltransferase SUV420H1 isoform 1. (885 aa)
GFERSulfhydryl oxidase. (205 aa)
SHLD1Shieldin complex subunit 1. (228 aa)
ENSMMUP00000078409Reverse transcriptase domain-containing protein. (850 aa)
LOC114669758Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (440 aa)
LPIN1Lipin 1. (975 aa)
ENSMMUP00000078516Endo/exonuclease/phosphatase domain-containing protein. (185 aa)
ENSMMUP00000078666Uncharacterized protein. (93 aa)
EP400E1A binding protein p400. (3045 aa)
PBRM1Polybromo 1. (1655 aa)
NRMNurim. (262 aa)
TP53BP1Tumor protein p53 binding protein 1. (1977 aa)
TERF2Telomeric repeat binding factor 2. (542 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (835 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa)
HELQHelicase, POLQ like. (1101 aa)
PHF10PHD finger protein 10. (563 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1586 aa)
CCT6AT-complex protein 1 subunit zeta isoform a. (531 aa)
RAD51AP1RAD51 associated protein 1. (352 aa)
HMBOX1Homeobox-containing protein 1. (420 aa)
HSF1Heat shock transcription factor 1. (507 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (471 aa)
HDAC10Histone deacetylase 10. (939 aa)
CYP1B1Uncharacterized protein; Belongs to the cytochrome P450 family. (542 aa)
CDT1Chromatin licensing and DNA replication factor 1. (551 aa)
CIZ1CDKN1A interacting zinc finger protein 1. (906 aa)
SHLD2FAM35_C domain-containing protein. (881 aa)
EYA3Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (579 aa)
ARID1AAT-rich interaction domain 1A. (2287 aa)
BCL7AB-cell CLL/lymphoma 7 protein family member A isoform a. (231 aa)
SYNCRIPSynaptotagmin binding cytoplasmic RNA interacting protein. (608 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
GNL3Guanine nucleotide-binding protein-like 3 isoform 1. (549 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
RGCCUncharacterized protein. (162 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
MGMTMethylated-DNA--protein-cysteine methyltransferase. (238 aa)
DHX36DEAH-box helicase 36. (1008 aa)
MCRS1Microspherule protein 1. (475 aa)
TOXThymocyte selection associated high mobility group box. (526 aa)
DERPCDERPC proline and glycine rich nuclear protein. (522 aa)
RFC5Replication factor C subunit 5 isoform 1. (340 aa)
KHDC3LKH domain containing 3 like, subcortical maternal complex member. (206 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1213 aa)
WT1WT1 transcription factor. (517 aa)
NPAS2Neuronal PAS domain-containing protein 2. (824 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (455 aa)
ACTL6AActin-like protein 6A isoform 1; Belongs to the actin family. (429 aa)
POLG2DNA polymerase gamma 2, accessory subunit. (485 aa)
LOC705671Uncharacterized protein. (398 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1132 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
GINS3GINS complex subunit 3. (255 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
WRAP53Telomerase Cajal body protein 1. (548 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
SLX4SLX4 structure-specific endonuclease subunit. (1668 aa)
TNKS2Poly [ADP-ribose] polymerase. (1258 aa)
ACTL6BActin like 6B; Belongs to the actin family. (449 aa)
SLX1AStructure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (437 aa)
DBF4Protein DBF4 homolog A. (675 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (603 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (648 aa)
FHFumarate hydratase, mitochondrial. (510 aa)
DHX9ATP-dependent RNA helicase A. (1275 aa)
FGFR4Fibroblast growth factor receptor. (859 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1102 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (661 aa)
SMARCE1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1. (411 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B isoform a. (332 aa)
FBXO4F-box protein 4. (490 aa)
BAXUncharacterized protein. (279 aa)
RFC2Replication factor C subunit 2. (233 aa)
PRDM9Uncharacterized protein. (482 aa)
RFC4Replication factor C subunit 4. (363 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform 1. (278 aa)
DPF1Zinc finger protein neuro-d4 isoform a. (414 aa)
RFC3Replication factor C subunit 3 isoform 1. (356 aa)
BCL7CUncharacterized protein. (242 aa)
FAM168AUncharacterized protein. (244 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (153 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
DSCC1DNA replication and sister chromatid cohesion 1. (393 aa)
INO80BINO80 complex subunit B. (356 aa)
PMLPromyelocytic leukemia protein. (882 aa)
ARID1BAT-rich interaction domain 1B. (2428 aa)
TFRCTransferrin receptor protein 1. (760 aa)
CTC1CST telomere replication complex component 1. (1267 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
NAF1Nuclear assembly factor 1 ribonucleoprotein. (497 aa)
BRD8Bromodomain containing 8. (1235 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1059 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa)
INO80DINO80 complex subunit D. (1027 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
CHTF18Chromosome transmission fidelity factor 18. (975 aa)
DBF4BDBF4 zinc finger B. (684 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa)
OOEPOocyte expressed protein. (149 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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