(42 nodes) Establishment of spindle orientation network (Macaca mulatta)

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Your Input:
	DYNLT1	Dynein light chain Tctex-type 1. (113 aa)
	NDC80	Kinetochore protein NDC80 homolog. (642 aa)
	PLK1	Serine/threonine-protein kinase PLK. (603 aa)
	PKHD1	PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4072 aa)
	NSFL1C	Uncharacterized protein. (372 aa)
	CENPA	Centromere protein A. (138 aa)
	DCTN1	CAP-Gly domain-containing protein. (1433 aa)
	MOS	Proto-oncogene serine/threonine-protein kinase mos; Belongs to the protein kinase superfamily. (346 aa)
	GPSM2	G-protein-signaling modulator 2. (686 aa)
	BCCIP	BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha. (323 aa)
	CLASP1	Cytoplasmic linker associated protein 1. (1533 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa)
	CDK5RAP2	CDK5 regulatory subunit associated protein 2. (1898 aa)
	ZW10	Zw10 kinetochore protein. (778 aa)
	PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (411 aa)
	INSC	INSC spindle orientation adaptor protein. (579 aa)
	MAP4	Microtubule-associated protein. (2279 aa)
	GPSM1	G protein signaling modulator 1. (683 aa)
	KIF25	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (891 aa)
	FBXW11	Uncharacterized protein. (563 aa)
	ANKFN1	Ankyrin repeat and fibronectin type III domain containing 1. (1149 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	ENSMMUP00000053583	HORMA domain-containing protein. (205 aa)
	ENSMMUP00000055202	Uncharacterized protein. (203 aa)
	FAM193A	Family with sequence similarity 193 member A. (1519 aa)
	SPRY1	Uncharacterized protein. (343 aa)
	MISP	Mitotic spindle positioning. (679 aa)
	NDE1	NudE neurodevelopment protein 1. (346 aa)
	SPRY2	Sprouty RTK signaling antagonist 2. (315 aa)
	MCPH1	Uncharacterized protein. (864 aa)
	MAD2L1	Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
	NUMA1	Nuclear mitotic apparatus protein 1. (2154 aa)
	MAPRE1	Microtubule-associated protein RP/EB family member 1. (268 aa)
	HTT	Huntingtin. (3170 aa)
	SPDL1	Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (622 aa)
	SPAG5	Sperm associated antigen 5. (1195 aa)
	GJA1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
	UBXN2B	UBX domain-containing protein 2B. (331 aa)
	PAX6	Uncharacterized protein. (598 aa)
	LLGL1	LLGL scribble cell polarity complex component 1. (1064 aa)
	MISP3	Uncharacterized protein. (387 aa)
	SAPCD2	Suppressor APC domain containing 2. (394 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK5RAP2	PLK1	ENSMMUP00000030614	ENSMMUP00000022766	CDK5 regulatory subunit associated protein 2.	Serine/threonine-protein kinase PLK.	0.649
CENPA	ENSMMUP00000053583	ENSMMUP00000020971	ENSMMUP00000053583	Centromere protein A.	HORMA domain-containing protein.	0.571
CENPA	MAD2L1	ENSMMUP00000020971	ENSMMUP00000070303	Centromere protein A.	Mitotic spindle assembly checkpoint protein MAD2A.	0.571
CENPA	NDC80	ENSMMUP00000020971	ENSMMUP00000024940	Centromere protein A.	Kinetochore protein NDC80 homolog.	0.770
CENPA	PLK1	ENSMMUP00000020971	ENSMMUP00000022766	Centromere protein A.	Serine/threonine-protein kinase PLK.	0.875
CENPA	SPAG5	ENSMMUP00000020971	ENSMMUP00000007906	Centromere protein A.	Sperm associated antigen 5.	0.750
CLASP1	DCTN1	ENSMMUP00000009845	ENSMMUP00000020487	Cytoplasmic linker associated protein 1.	CAP-Gly domain-containing protein.	0.619
CLASP1	ENSMMUP00000053583	ENSMMUP00000009845	ENSMMUP00000053583	Cytoplasmic linker associated protein 1.	HORMA domain-containing protein.	0.449
CLASP1	MAD2L1	ENSMMUP00000009845	ENSMMUP00000070303	Cytoplasmic linker associated protein 1.	Mitotic spindle assembly checkpoint protein MAD2A.	0.449
CLASP1	MAPRE1	ENSMMUP00000009845	ENSMMUP00000072401	Cytoplasmic linker associated protein 1.	Microtubule-associated protein RP/EB family member 1.	0.536
CLASP1	PLK1	ENSMMUP00000009845	ENSMMUP00000022766	Cytoplasmic linker associated protein 1.	Serine/threonine-protein kinase PLK.	0.762
CLASP1	SPAG5	ENSMMUP00000009845	ENSMMUP00000007906	Cytoplasmic linker associated protein 1.	Sperm associated antigen 5.	0.403
DCTN1	CLASP1	ENSMMUP00000020487	ENSMMUP00000009845	CAP-Gly domain-containing protein.	Cytoplasmic linker associated protein 1.	0.619
DCTN1	DYNLT1	ENSMMUP00000020487	ENSMMUP00000025567	CAP-Gly domain-containing protein.	Dynein light chain Tctex-type 1.	0.428
DCTN1	HTT	ENSMMUP00000020487	ENSMMUP00000073896	CAP-Gly domain-containing protein.	Huntingtin.	0.622
DCTN1	MAPRE1	ENSMMUP00000020487	ENSMMUP00000072401	CAP-Gly domain-containing protein.	Microtubule-associated protein RP/EB family member 1.	0.900
DCTN1	NDE1	ENSMMUP00000020487	ENSMMUP00000066556	CAP-Gly domain-containing protein.	NudE neurodevelopment protein 1.	0.476
DCTN1	NUMA1	ENSMMUP00000020487	ENSMMUP00000070591	CAP-Gly domain-containing protein.	Nuclear mitotic apparatus protein 1.	0.473
DCTN1	PAFAH1B1	ENSMMUP00000020487	ENSMMUP00000035424	CAP-Gly domain-containing protein.	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]	0.870
DCTN1	PLK1	ENSMMUP00000020487	ENSMMUP00000022766	CAP-Gly domain-containing protein.	Serine/threonine-protein kinase PLK.	0.755