(61 nodes) Establishment of chromosome localization network (Macaca mulatta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	RRS1	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
	NUF2	Kinetochore protein Nuf2. (464 aa)
	CDC23	Cell division cycle protein 23 homolog. (597 aa)
	CHMP4C	Charged multivesicular body protein 4C. (233 aa)
	ATM	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
	KIF14	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1649 aa)
	CHMP4B	Charged multivesicular body protein 4B. (224 aa)
	KIF22	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (670 aa)
	H9H3J4_MACMU	Uncharacterized protein. (142 aa)
	SPICE1	Uncharacterized protein. (860 aa)
	KIF18A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (897 aa)
	CDT1	Chromatin licensing and DNA replication factor 1. (551 aa)
	CDCA8	Cell division cycle associated 8. (280 aa)
	CCDC155	Coiled-coil domain containing 155. (575 aa)
	MEIOC	Meiosis specific with coiled-coil domain. (955 aa)
	PSRC1	Proline/serine-rich coiled-coil protein 1 isoform a. (332 aa)
	CENPF	Centromere protein F. (3113 aa)
	CHMP7	Charged multivesicular body protein 7. (453 aa)
	EML3	EMAP like 3. (868 aa)
	CDCA5	Cell division cycle associated 5. (252 aa)
	NDC80	Kinetochore protein NDC80 homolog. (642 aa)
	KPNB1	Karyopherin subunit beta 1. (856 aa)
	CHMP5	Charged multivesicular body protein 5 isoform 1. (219 aa)
	MLH1	MutL homolog 1. (756 aa)
	CHAMP1	Chromosome alignment maintaining phosphoprotein 1. (813 aa)
	ZW10	Zw10 kinetochore protein. (778 aa)
	NUP62	Nuclear pore glycoprotein p62. (521 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (396 aa)
	CCNB1	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa)
	CENPE	Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2701 aa)
	CUL3	Cullin-3; Belongs to the cullin family. (768 aa)
	DCTN2	Dynactin subunit 2. (448 aa)
	KIF2C	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
	MAP1S	Uncharacterized protein. (1163 aa)
	NUDC	Nuclear migration protein nudC. (332 aa)
	CENPQ	Centromere protein Q. (268 aa)
	BIRC5	Baculoviral IAP repeat-containing protein 5 isoform 1. (142 aa)
	KIFC1	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (849 aa)
	ENSMMUP00000048438	Uncharacterized protein. (263 aa)
	CHMP2B	Charged multivesicular body protein 2B. (225 aa)
	KLF5	Uncharacterized protein. (1062 aa)
	MAJIN	Membrane anchored junction protein. (216 aa)
	GEM	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
	TERB2	Uncharacterized protein. (221 aa)
	RMDN1	Regulator of microtubule dynamics 1. (314 aa)
	EML4	EMAP like 4. (1051 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (718 aa)
	MIS12	Protein MIS12 homolog. (205 aa)
	NDE1	NudE neurodevelopment protein 1. (346 aa)
	TERB1	Telomere repeat binding bouquet formation protein 1. (738 aa)
	ANKRD53	Ankyrin repeat domain 53. (529 aa)
	CHMP2A	Charged multivesicular body protein 2a. (222 aa)
	CHMP6	Uncharacterized protein. (259 aa)
	MAPRE1	Microtubule-associated protein RP/EB family member 1. (268 aa)
	INCENP	Inner centromere protein. (900 aa)
	CHMP4A-2	Uncharacterized protein. (279 aa)
	SUN1	Sad1 and UNC84 domain containing 1. (1065 aa)
	SPDL1	Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (622 aa)
	TRAPPC12	Trafficking protein particle complex 12. (756 aa)
	CENPC	Centromere protein C. (950 aa)
	PINX1	PIN2 (TERF1) interacting telomerase inhibitor 1. (452 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	CCNB1	ENSMMUP00000005561	ENSMMUP00000034570	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family.	0.543
ATM	CDT1	ENSMMUP00000005561	ENSMMUP00000018173	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Chromatin licensing and DNA replication factor 1.	0.505
ATM	MLH1	ENSMMUP00000005561	ENSMMUP00000029670	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	MutL homolog 1.	0.884
ATM	SPO11	ENSMMUP00000005561	ENSMMUP00000000347	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	SPO11 initiator of meiotic double stranded breaks.	0.790
BIRC5	CCNB1	ENSMMUP00000046523	ENSMMUP00000034570	Baculoviral IAP repeat-containing protein 5 isoform 1.	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family.	0.811
BIRC5	CDCA5	ENSMMUP00000046523	ENSMMUP00000024699	Baculoviral IAP repeat-containing protein 5 isoform 1.	Cell division cycle associated 5.	0.484
BIRC5	CDCA8	ENSMMUP00000046523	ENSMMUP00000018838	Baculoviral IAP repeat-containing protein 5 isoform 1.	Cell division cycle associated 8.	0.996
BIRC5	CDT1	ENSMMUP00000046523	ENSMMUP00000018173	Baculoviral IAP repeat-containing protein 5 isoform 1.	Chromatin licensing and DNA replication factor 1.	0.527
BIRC5	CENPE	ENSMMUP00000046523	ENSMMUP00000034930	Baculoviral IAP repeat-containing protein 5 isoform 1.	Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.719
BIRC5	CENPF	ENSMMUP00000046523	ENSMMUP00000020521	Baculoviral IAP repeat-containing protein 5 isoform 1.	Centromere protein F.	0.714
BIRC5	CENPQ	ENSMMUP00000046523	ENSMMUP00000046016	Baculoviral IAP repeat-containing protein 5 isoform 1.	Centromere protein Q.	0.423
BIRC5	INCENP	ENSMMUP00000046523	ENSMMUP00000072578	Baculoviral IAP repeat-containing protein 5 isoform 1.	Inner centromere protein.	0.972
BIRC5	KIF22	ENSMMUP00000046523	ENSMMUP00000012667	Baculoviral IAP repeat-containing protein 5 isoform 1.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.704
BIRC5	KIF2C	ENSMMUP00000046523	ENSMMUP00000040325	Baculoviral IAP repeat-containing protein 5 isoform 1.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.846
BIRC5	KIFC1	ENSMMUP00000046523	ENSMMUP00000046588	Baculoviral IAP repeat-containing protein 5 isoform 1.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.587
BIRC5	NDC80	ENSMMUP00000046523	ENSMMUP00000024940	Baculoviral IAP repeat-containing protein 5 isoform 1.	Kinetochore protein NDC80 homolog.	0.727
BIRC5	NUF2	ENSMMUP00000046523	ENSMMUP00000001531	Baculoviral IAP repeat-containing protein 5 isoform 1.	Kinetochore protein Nuf2.	0.769
CCDC155	MAJIN	ENSMMUP00000019419	ENSMMUP00000055190	Coiled-coil domain containing 155.	Membrane anchored junction protein.	0.497
CCDC155	SUN1	ENSMMUP00000019419	ENSMMUP00000074040	Coiled-coil domain containing 155.	Sad1 and UNC84 domain containing 1.	0.951
CCDC155	TERB1	ENSMMUP00000019419	ENSMMUP00000067472	Coiled-coil domain containing 155.	Telomere repeat binding bouquet formation protein 1.	0.533