(9 nodes) Bergmann glial cell differentiation network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	TTC21B	Tetratricopeptide repeat domain 21B. (1316 aa)
	PLPP3	acidPPc domain-containing protein. (353 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	GPR37L1	G protein-coupled receptor 37 like 1. (491 aa)
	ABL1	Tyrosine-protein kinase. (1149 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	GFAP	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (462 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	MAPK1	ENSMMUP00000053665	ENSMMUP00000016444	Tyrosine-protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.544
ABL1	MAPK3	ENSMMUP00000053665	ENSMMUP00000053373	Tyrosine-protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.471
GFAP	SHH	ENSMMUP00000046183	ENSMMUP00000065431	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.539
MAPK1	ABL1	ENSMMUP00000016444	ENSMMUP00000053665	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Tyrosine-protein kinase.	0.544
MAPK1	MAPK3	ENSMMUP00000016444	ENSMMUP00000053373	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.982
MAPK1	PTPN11	ENSMMUP00000016444	ENSMMUP00000050217	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.947
MAPK3	ABL1	ENSMMUP00000053373	ENSMMUP00000053665	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Tyrosine-protein kinase.	0.471
MAPK3	MAPK1	ENSMMUP00000053373	ENSMMUP00000016444	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.982
MAPK3	PTPN11	ENSMMUP00000053373	ENSMMUP00000050217	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.960
PTPN11	MAPK1	ENSMMUP00000050217	ENSMMUP00000016444	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.947
PTPN11	MAPK3	ENSMMUP00000050217	ENSMMUP00000053373	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.960
SHH	GFAP	ENSMMUP00000065431	ENSMMUP00000046183	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.539