STRINGSTRING
BMP5 BMP5 FGF8 FGF8 SIX4 SIX4 BMP7 BMP7 PLXNA2 PLXNA2 NOG NOG GATA3 GATA3 BMPR2 BMPR2 ECE1 ECE1 ACVR1 ACVR1 BMPR1A BMPR1A BMP4 BMP4 NKX2-5 NKX2-5 HOXA2 HOXA2 TGFB2 TGFB2 ISL1 ISL1 EDN1 EDN1 EYA1 EYA1 TBX1 TBX1 TGFBR1 TGFBR1 PTCH1 PTCH1 RIPPLY3 RIPPLY3 NKX3-1 NKX3-1 EDNRA EDNRA ADGRF5 ADGRF5 NKX2-6 NKX2-6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP5Bone morphogenetic protein 5. (454 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SIX4SIX homeobox 4. (772 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
PLXNA2Plexin A2. (1909 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GATA3GATA binding protein 3. (444 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ECE1Endothelin converting enzyme 1. (780 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
NKX2-5NK2 homeobox 5. (324 aa)
HOXA2Homeobox A2. (374 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ISL1ISL LIM homeobox 1. (413 aa)
EDN1Preproendothelin-1. (211 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
TBX1T-box transcription factor 1. (496 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
PTCH1Patched 1. (1452 aa)
RIPPLY3Ripply transcriptional repressor 3. (184 aa)
NKX3-1Homeobox protein Nkx-3.1. (232 aa)
EDNRAUncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1383 aa)
NKX2-6NK2 homeobox 6. (301 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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