STRINGSTRING
NKX2-5 NKX2-5 FOXC2 FOXC2 TGFBR3 TGFBR3 FOXC1 FOXC1 FGF9 FGF9 TBX5 TBX5 MAPK11 MAPK11 BMP10 BMP10 ARID2 ARID2 NOTCH1 NOTCH1 SMAD1 SMAD1 JARID2 JARID2 DIPK2A DIPK2A NDRG4 NDRG4 SAV1 SAV1 WNT2 WNT2 HEY2 HEY2 TGFB2 TGFB2 TENM4 TENM4 GATA6 GATA6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NKX2-5NK2 homeobox 5. (324 aa)
FOXC2Forkhead box C2. (471 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
FOXC1Forkhead box C1. (551 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TBX5T-box transcription factor 5. (518 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
NOTCH1Notch receptor 1. (2556 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1281 aa)
DIPK2ADivergent protein kinase domain 2A. (458 aa)
NDRG4NDRG family member 4. (494 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TENM4Teneurin transmembrane protein 4. (2929 aa)
GATA6Transcription factor GATA-6. (595 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.