STRINGSTRING
BSG BSG IHH IHH LAMC3 LAMC3 CLIC4 CLIC4 HIPK2 HIPK2 PDE6B PDE6B MAN2A1 MAN2A1 LHX2 LHX2 BAX BAX FZD4 FZD4 MAX MAX TTC8 TTC8 PDE6A PDE6A TULP1 TULP1 RS1 RS1 ZHX2 ZHX2 IMPDH2 IMPDH2 GNAT2 GNAT2 USP45 USP45 GDF11 GDF11 CRB2 CRB2 CALB1 CALB1 COL4A1 COL4A1 CLCN2 CLCN2 CDON CDON MEGF11 MEGF11 RHOJ RHOJ NEUROD1 NEUROD1 ARHGEF15 ARHGEF15 THY1 THY1 BMPR2 BMPR2 PAX2 PAX2 AHI1 AHI1 ACTL6A ACTL6A MERTK MERTK SKI SKI MFSD2A MFSD2A IMPG2 IMPG2 LAMA1 LAMA1 PDGFRB PDGFRB CHD7 CHD7 SMARCA4 SMARCA4 CRB1 CRB1 IGFN1 IGFN1 BBS4 BBS4 CYP1B1 CYP1B1 PDE6C PDE6C SLC17A7 SLC17A7 ATOH7 ATOH7 RET RET PAX4 PAX4 SLC4A5 SLC4A5 NOTCH1 NOTCH1 GRM6 GRM6 SLC17A8 SLC17A8 ACVR2B ACVR2B NR2E3 NR2E3 SDK1 SDK1 ATP2B2 ATP2B2 GNAT1 GNAT1 FOXN4 FOXN4 RPGRIP1L RPGRIP1L DLL1 DLL1 PFDN5 PFDN5 RDH13 RDH13 NPHP1 NPHP1 NPHP4 NPHP4 TCIRG1 TCIRG1 TSPAN12 TSPAN12 ATP2B1 ATP2B1 USH1C USH1C RPGRIP1 RPGRIP1 PROM1 PROM1 NRP1 NRP1 HPCAL1 HPCAL1 LRP5 LRP5 NDUFB6 NDUFB6 HIPK1 HIPK1 LOC713290 LOC713290 ACVRL1 ACVRL1 FJX1 FJX1 ENSMMUP00000043582 ENSMMUP00000043582 STAT3 STAT3 RP1L1 RP1L1 RORB RORB NECTIN3 NECTIN3 BMPR1B BMPR1B GPM6A GPM6A DCX DCX RPL24 RPL24 BHLHE23 BHLHE23 VSTM4 VSTM4 LAMB2 LAMB2 TFAP2A TFAP2A CASP2 CASP2 HIF1A HIF1A PTPRM PTPRM JMJD6 JMJD6 OBSL1 OBSL1 HPS1 HPS1 CLN8 CLN8 MED1 MED1 TENT2 TENT2 RP1 RP1 RHO RHO ACHE ACHE IGSF22 IGSF22 HPCA HPCA TGFB2 TGFB2 LOC722798 LOC722798 VAX2 VAX2 NECTIN1 NECTIN1 RPE65 RPE65 AGTPBP1 AGTPBP1 RD3 RD3 PROX1 PROX1 ATP8A2 ATP8A2 TUB TUB SOX8 SOX8 TTLL5 TTLL5 NR2E1 NR2E1 POU4F2 POU4F2 VSX1 VSX1 SMARCD3 SMARCD3 SERPINF1 SERPINF1 NEUROD4 NEUROD4 NDP NDP SOX9 SOX9 ZNF513 ZNF513 TBC1D32 TBC1D32 NTRK2 NTRK2 BARHL2 BARHL2 PTF1A PTF1A THRB THRB DCLK1 DCLK1 DTNBP1 DTNBP1 LPCAT1 LPCAT1 FAT3 FAT3 CABP4 CABP4 PRPH2 PRPH2 PAX6 PAX6 ATP2B4 ATP2B4 SCAPER SCAPER TGIF2 TGIF2 NAGLU NAGLU DSCAM DSCAM TFAP2B TFAP2B ROM1 ROM1 SLC1A1 SLC1A1 NRL NRL HCN1 HCN1 SDK2 SDK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BSGUncharacterized protein. (588 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
LAMC3Laminin subunit gamma 3. (1575 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
HIPK2Homeodomain interacting protein kinase 2. (1212 aa)
PDE6BPhosphodiesterase. (839 aa)
MAN2A1Alpha-mannosidase. (1143 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
BAXUncharacterized protein. (279 aa)
FZD4Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
MAXMYC associated factor X. (160 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
PDE6APhosphodiesterase. (860 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (542 aa)
RS1Retinoschisin 1. (224 aa)
ZHX2Zinc fingers and homeoboxes protein 2. (837 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (538 aa)
GNAT2G protein subunit alpha transducin 2. (354 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (815 aa)
GDF11Growth differentiation factor 11. (408 aa)
CRB2Crumbs cell polarity complex component 2. (1287 aa)
CALB1Calbindin 1. (261 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
CLCN2Chloride channel protein. (898 aa)
CDONCell adhesion associated, oncogene regulated. (1339 aa)
MEGF11Multiple EGF like domains 11. (1044 aa)
RHOJRho-related GTP-binding protein RhoJ. (214 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (841 aa)
THY1Thy-1 membrane glycoprotein; May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. (177 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
PAX2Paired box 2. (418 aa)
AHI1Abelson helper integration site 1. (1196 aa)
ACTL6AActin-like protein 6A isoform 1; Belongs to the actin family. (429 aa)
MERTKMER proto-oncogene, tyrosine kinase. (1232 aa)
SKISKI proto-oncogene. (730 aa)
MFSD2AMajor facilitator superfamily domain-containing protein 2A isoform 2. (530 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1242 aa)
LAMA1Uncharacterized protein. (528 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2998 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
IGFN1Uncharacterized protein. (1282 aa)
BBS4Bardet-Biedl syndrome 4 protein. (519 aa)
CYP1B1Uncharacterized protein; Belongs to the cytochrome P450 family. (542 aa)
PDE6CPhosphodiesterase. (858 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
ATOH7Atonal bHLH transcription factor 7. (152 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
PAX4Paired box 4. (343 aa)
SLC4A5Anion exchange protein. (1136 aa)
NOTCH1Notch receptor 1. (2556 aa)
GRM6Glutamate metabotropic receptor 6. (877 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
NR2E3Nuclear receptor subfamily 2 group E member 3. (410 aa)
SDK1Sidekick cell adhesion molecule 1. (2213 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
GNAT1G protein subunit alpha i2. (350 aa)
FOXN4Forkhead box N4. (517 aa)
RPGRIP1LC2 domain-containing protein. (1273 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
PFDN5Prefoldin subunit 5 isoform alpha. (154 aa)
RDH13Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
NPHP1Nephrocystin 1. (735 aa)
NPHP4Nephrocystin 4. (1509 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (853 aa)
TSPAN12Tetraspanin. (305 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
USH1CUSH1 protein network component harmonin. (899 aa)
RPGRIP1RPGR interacting protein 1. (1235 aa)
PROM1Prominin 1. (855 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
HPCAL1Hippocalcin like 1. (238 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1612 aa)
NDUFB6RING-type domain-containing protein. (1085 aa)
HIPK1Uncharacterized protein. (1598 aa)
LOC713290Uncharacterized protein. (702 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
FJX1Four-jointed box kinase 1. (437 aa)
ENSMMUP00000043582TRASH domain-containing protein. (157 aa)
STAT3Signal transducer and activator of transcription. (871 aa)
RP1L1RP1 like 1. (1566 aa)
RORBNuclear receptor ROR-beta. (459 aa)
NECTIN3Nectin cell adhesion molecule 3. (549 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GPM6ANeuronal membrane glycoprotein M6-a isoform 2. (278 aa)
DCXDoublecortin. (387 aa)
RPL24TRASH domain-containing protein. (163 aa)
BHLHE23Basic helix-loop-helix family member e23. (241 aa)
VSTM4V-set and transmembrane domain containing 4. (370 aa)
LAMB2Laminin subunit beta-2. (1798 aa)
TFAP2ATranscription factor AP-2 alpha. (445 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (826 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1465 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (436 aa)
OBSL1Obscurin like 1. (1896 aa)
HPS1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (700 aa)
CLN8Protein CLN8. (286 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
TENT2Terminal nucleotidyltransferase 2. (484 aa)
RP1RP1 axonemal microtubule associated. (2152 aa)
RHORhodopsin. (348 aa)
ACHEUncharacterized protein; Belongs to the type-B carboxylesterase/lipase family. (848 aa)
IGSF22Immunoglobulin superfamily member 22. (1326 aa)
HPCANeuron-specific calcium-binding protein hippocalcin. (193 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LOC722798Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
VAX2Ventral anterior homeobox 2. (290 aa)
NECTIN1Poliovirus receptor-related protein 1 isoform 1. (519 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
AGTPBP1ATP/GTP binding protein 1. (1226 aa)
RD3Retinal degeneration 3, GUCY2D regulator. (195 aa)
PROX1Prospero homeobox protein 1. (737 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1291 aa)
TUBTubby-like protein; Belongs to the TUB family. (584 aa)
SOX8SRY-box transcription factor 8. (617 aa)
TTLL5Tubulin tyrosine ligase like 5. (1345 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (390 aa)
POU4F2POU domain protein. (408 aa)
VSX1Visual system homeobox 1. (365 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (533 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
NEUROD4Neurogenic differentiation factor. (331 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
ZNF513Zinc finger protein 513 isoform 1. (541 aa)
TBC1D32TBC1 domain family member 32. (1334 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
BARHL2BarH like homeobox 2. (356 aa)
PTF1APancreas associated transcription factor 1a. (329 aa)
THRBThyroid hormone receptor beta. (524 aa)
DCLK1Doublecortin like kinase 1. (759 aa)
DTNBP1Dystrobrevin binding protein 1. (425 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (688 aa)
FAT3FAT atypical cadherin 3. (4612 aa)
CABP4Calcium binding protein 4. (303 aa)
PRPH2Peripherin 2. (346 aa)
PAX6Uncharacterized protein. (598 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
SCAPERS-phase cyclin A associated protein in the ER. (1400 aa)
TGIF25'-TG-3'-interacting factor 2. (237 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
DSCAMDS cell adhesion molecule. (2010 aa)
TFAP2BTranscription factor AP-2 beta. (504 aa)
ROM1Rod outer segment membrane protein 1. (351 aa)
SLC1A1Excitatory amino acid transporter 3. (524 aa)
NRLNeural retina leucine zipper. (239 aa)
HCN1Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (885 aa)
SDK2Sidekick cell adhesion molecule 2. (2172 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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