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GRIK5 GRIK5 NPAS4 NPAS4 CHRNA4 CHRNA4 LRRK2 LRRK2 P2RX2 P2RX2 GABRR1 GABRR1 CDK5 CDK5 GLRA1 GLRA1 HTR3C HTR3C GABRE GABRE CHRNA5 CHRNA5 GABRA4 GABRA4 GLRA3 GLRA3 P2RX1 P2RX1 CHRNB4 CHRNB4 HTR3B HTR3B S1PR2 S1PR2 HCRT HCRT GRIN2D GRIN2D CHRNA10 CHRNA10 P2RX6 P2RX6 SEZ6 SEZ6 CHRNA1 CHRNA1 CHRNG CHRNG CHRNA7 CHRNA7 P2RX5 P2RX5 GABRA5 GABRA5 GABRG3 GABRG3 CHRNA3 CHRNA3 GLRB GLRB MPP6 MPP6 CHRNA9 CHRNA9 TRPV1 TRPV1 LOC719678 LOC719678 P2RX7 P2RX7 GABRR3 GABRR3 GRIN1 GRIN1 MEF2C MEF2C GRIK2 GRIK2 MPP2 MPP2 GRIN2A GRIN2A DGKI DGKI CHRNA6 CHRNA6 CHRND CHRND RAB3GAP1 RAB3GAP1 HTR3D HTR3D MECP2 MECP2 P2RX4 P2RX4 GABRB1 GABRB1 CHRNA2 CHRNA2 HTR3E HTR3E PPP3CA PPP3CA GSK3B GSK3B AKT1 AKT1 GABRQ GABRQ P2RX3 P2RX3 GABRA6 GABRA6 GHRL GHRL CHRNB3 CHRNB3 ZACN ZACN HTR3A HTR3A CHRNE CHRNE GABRD GABRD GABRA3 GABRA3 GRIN2C GRIN2C GABRG1 GABRG1 GABRB3 GABRB3 GLRA2 GLRA2 MAPK8IP2 MAPK8IP2 CHRNB2 CHRNB2 GABRA2 GABRA2 GLRA4 GLRA4 GRID2 GRID2 GABRP GABRP GABRR2 GABRR2 GRIN2B GRIN2B GABRB2 GABRB2 CHRNB1 CHRNB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (1388 aa)
NPAS4Neuronal PAS domain protein 4. (802 aa)
CHRNA4Uncharacterized protein. (625 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (496 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (480 aa)
CDK5Cyclin dependent kinase 5. (364 aa)
GLRA1Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (449 aa)
HTR3C5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (432 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (506 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (468 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (554 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (492 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
S1PR2Sphingosine 1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (353 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1336 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (479 aa)
SEZ6Seizure protein 6 homolog isoform 1. (996 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (502 aa)
CHRNGCholinergic receptor nicotinic gamma subunit. (516 aa)
CHRNA7Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin (By similarity). (502 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (402 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (497 aa)
GLRBGlycine receptor subunit beta isoform A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
MPP6Membrane palmitoylated protein 6; Belongs to the MAGUK family. (555 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (839 aa)
LOC719678Uncharacterized protein. (626 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (573 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (469 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform 1. (473 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
MPP2Uncharacterized protein; Belongs to the MAGUK family. (594 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
DGKIDiacylglycerol kinase. (1100 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (573 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (989 aa)
HTR3D5-hydroxytryptamine receptor 3D. (440 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (467 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (530 aa)
HTR3E5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (420 aa)
PPP3CASerine/threonine-protein phosphatase. (547 aa)
GSK3BGlycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily. (433 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (632 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (468 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
GHRLGhrelin and obestatin prepropeptide. (222 aa)
CHRNB3Neuronal acetylcholine receptor subunit beta-3. (458 aa)
ZACNZinc activated ion channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (407 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (485 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (493 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (484 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (492 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1317 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (478 aa)
GABRB3Gamma-aminobutyric acid receptor subunit beta-3 isoform 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (936 aa)
CHRNB2Neuronal acetylcholine receptor subunit beta-2. (502 aa)
GABRA2Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (460 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
GABRB2Gamma-aminobutyric acid receptor subunit beta-2; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present [...] (512 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (501 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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