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TBC1D32 | TBC1 domain family member 32. (1334 aa) | ||||
TEAD4 | TUB like protein 3; Belongs to the TUB family. (728 aa) | ||||
SUFU | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (500 aa) | ||||
WDR19 | WD_REPEATS_REGION domain-containing protein. (1348 aa) | ||||
PTCH1 | Patched 1. (1452 aa) | ||||
GLI3 | GLI family zinc finger 3. (1580 aa) |