STRINGSTRING
TGFBR3 TGFBR3 COL11A2 COL11A2 WNT3A WNT3A ITGB8 ITGB8 TGFBR2 TGFBR2 FZD2 FZD2 CHD7 CHD7 TGFB3 TGFB3 SMAD4 SMAD4 WNT7A WNT7A LRRC32 LRRC32 WNT8A WNT8A DLG1 DLG1 FOXE1 FOXE1 LEF1 LEF1 SMAD2 SMAD2 TBX1 TBX1 ITGB6 ITGB6 SOX11 SOX11 WNT11 WNT11 TGFB2 TGFB2 WNT5A WNT5A JAG2 JAG2 TSHZ1 TSHZ1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
COL11A2Collagen type XI alpha 2 chain. (1676 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (822 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2998 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
LRRC32Leucine rich repeat containing 32. (662 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
DLG1Disks large homolog 1 isoform 2; Belongs to the MAGUK family. (926 aa)
FOXE1Forkhead box E1. (372 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TBX1T-box transcription factor 1. (496 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
SOX11Transcription factor SOX. (441 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (462 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1290 aa)
TSHZ1Teashirt zinc finger homeobox 1. (1097 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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