STRINGSTRING
IGF1 IGF1 IQGAP3 IQGAP3 F7FM70_MACMU F7FM70_MACMU DUSP7 DUSP7 F6V457_MACMU F6V457_MACMU TF TF EGF EGF CTSH CTSH HTR2B HTR2B MAPK1 MAPK1 NOD1 NOD1 KDR KDR MYC MYC WNK4 WNK4 TBC1D10C TBC1D10C TNFSF11 TNFSF11 SMAD4 SMAD4 F6YF69_MACMU F6YF69_MACMU FGF18 FGF18 ITGAV ITGAV GRB10 GRB10 F6YRT5_MACMU F6YRT5_MACMU RIPK2 RIPK2 MT3 MT3 LOC114670311 LOC114670311 LOC723080 LOC723080 F6RVH3_MACMU F6RVH3_MACMU F6RVG4_MACMU F6RVG4_MACMU F6W9C6_MACMU F6W9C6_MACMU TLR4 TLR4 BRAF BRAF NOD2 NOD2 ZFP36L1 ZFP36L1 MAPK3 MAPK3 FGF10 FGF10 ABL1 ABL1 ENSMMUP00000054772 ENSMMUP00000054772 HESX1 HESX1 DUSP9 DUSP9 EDN1 EDN1 SPRY1 SPRY1 ENSMMUP00000063650 ENSMMUP00000063650 LOC713341 LOC713341 ENSMMUP00000064444 ENSMMUP00000064444 ANKRD26 ANKRD26 DUSP6 DUSP6 FGF23 FGF23 SPRY2 SPRY2 ZFP36L2 ZFP36L2 AVP AVP C1QL4 C1QL4 SOX9 SOX9 LOC706905 LOC706905 DUSP5 DUSP5 FLCN FLCN KARS1 KARS1 ANKRD30A ANKRD30A LOC114675655 LOC114675655 ENSMMUP00000077846 ENSMMUP00000077846 ENSMMUP00000078548 ENSMMUP00000078548 ENSMMUP00000080620 ENSMMUP00000080620
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IGF1Insulin like growth factor 1. (208 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1631 aa)
F7FM70_MACMUANK_REP_REGION domain-containing protein. (167 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
F6V457_MACMUUncharacterized protein. (129 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1213 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (471 aa)
WNK4WNK lysine deficient protein kinase 4. (1242 aa)
TBC1D10CCarabin. (446 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
F6YF69_MACMUUncharacterized protein. (673 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ITGAVIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1051 aa)
GRB10Uncharacterized protein. (631 aa)
F6YRT5_MACMUUncharacterized protein. (89 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa)
LOC114670311ANK_REP_REGION domain-containing protein. (545 aa)
LOC723080ANK_REP_REGION domain-containing protein. (526 aa)
F6RVH3_MACMUANK_REP_REGION domain-containing protein. (288 aa)
F6RVG4_MACMUANK_REP_REGION domain-containing protein. (475 aa)
F6W9C6_MACMUUncharacterized protein. (118 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1044 aa)
ZFP36L1ZFP36 ring finger protein like 1. (344 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
ENSMMUP00000054772ANK_REP_REGION domain-containing protein. (330 aa)
HESX1HESX homeobox 1. (185 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
EDN1Preproendothelin-1. (211 aa)
SPRY1Uncharacterized protein. (343 aa)
ENSMMUP00000063650Uncharacterized protein. (79 aa)
LOC713341ANK_REP_REGION domain-containing protein. (627 aa)
ENSMMUP00000064444DUF3496 domain-containing protein. (72 aa)
ANKRD26Ankyrin repeat domain 26. (2064 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
ZFP36L2Zinc finger protein 36, C3H1 type-like 2. (492 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
C1QL4Complement C1q like 4. (241 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
LOC706905ANK_REP_REGION domain-containing protein. (618 aa)
DUSP5Dual specificity phosphatase 5. (506 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (680 aa)
KARS1Lysine--tRNA ligase. (650 aa)
ANKRD30AAnkyrin repeat domain 30A. (1174 aa)
LOC114675655ANK_REP_REGION domain-containing protein. (649 aa)
ENSMMUP00000077846DUF3496 domain-containing protein. (141 aa)
ENSMMUP00000078548ANK_REP_REGION domain-containing protein. (299 aa)
ENSMMUP00000080620Uncharacterized protein. (640 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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