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| | LIMD1 | LIM domains containing 1. (676 aa) |
| | EGLN3 | Egl nine homolog 3. (239 aa) |
| | HIF3A | Hypoxia inducible factor 3 subunit alpha. (869 aa) |
| | ANGPT4 | Angiopoietin 4. (503 aa) |
| | PDLIM1 | PDZ and LIM domain 1. (330 aa) |
| | FNDC1 | Fibronectin type III domain containing 1. (1991 aa) |
| | ARNT | Uncharacterized protein. (786 aa) |
| | ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2. (711 aa) |
| | RYR2 | Ryanodine receptor 2. (4967 aa) |
| | H9H2Q7_MACMU | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (364 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | ASCL2 | Achaete-scute family bHLH transcription factor 2. (193 aa) |
| | CPEB2 | Cytoplasmic polyadenylation element binding protein 2. (1037 aa) |
| | COL1A1 | Collagen alpha-1(I) chain preproprotein. (1464 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (860 aa) |
| | USF1 | Upstream transcription factor 1. (366 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1212 aa) |
| | PML | Promyelocytic leukemia protein. (882 aa) |
| | SOD3 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa) |
| | PICK1 | Protein interacting with PRKCA 1. (600 aa) |
| | SCN2A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa) |
| | RYR1 | Ryanodine receptor 1. (4928 aa) |
| | MPL | MPL proto-oncogene, thrombopoietin receptor. (635 aa) |
| | AQP3 | Aquaporin-3; Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa) |
| | FUNDC1 | FUN14 domain-containing protein 1. (155 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa) |
| | TH | Tyrosine hydroxylase. (501 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | NOX1 | NADPH oxidase 1. (564 aa) |
| | MIEF1 | Mitochondrial elongation factor 1. (478 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (249 aa) |
| | AIFM1 | Apoptosis-inducing factor 1, mitochondrial isoform 1. (613 aa) |
| | THBS1 | Thrombospondin 1. (1170 aa) |
| | MYOD1 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa) |
| | CIAO3 | Fe_hyd_SSU domain-containing protein; Belongs to the NARF family. (476 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (664 aa) |
| | HIF1AN | Hypoxia inducible factor 1 subunit alpha inhibitor. (397 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | PENK | Proenkephalin. (300 aa) |
| | NF1 | Neurofibromin 1. (2867 aa) |
| | LPAR1 | Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | F7E5P0_MACMU | Uncharacterized protein. (587 aa) |
| | HSD11B2 | Hydroxysteroid 11-beta dehydrogenase 2. (405 aa) |
| | DPP4 | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa) |
| | ALAS2 | 5-aminolevulinate synthase. (587 aa) |
| | PTEN | Uncharacterized protein. (589 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (433 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1189 aa) |
| | TBL2 | Transducin beta-like protein 2. (446 aa) |
| | CYB5R4 | Cytochrome b5 reductase 4. (627 aa) |
| | CCNA2 | Cyclin-A2; Belongs to the cyclin family. (432 aa) |
| | CARD17 | Caspase recruitment domain family member 17. (110 aa) |
| | PLAU | Plasminogen activator, urokinase. (430 aa) |
| | TSC1 | TSC complex subunit 1. (1164 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | NDRG1 | N-myc downstream regulated 1. (394 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1130 aa) |
| | BACH1 | Uncharacterized protein. (763 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (495 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | RGCC | Uncharacterized protein. (162 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | ATP7A | ATPase copper transporting alpha. (1500 aa) |
| | ADAM17 | Disintegrin and metalloproteinase domain-containing protein 17 preproprotein. (824 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | MYOCD | Myocardin. (986 aa) |
| | NOP53 | Uncharacterized protein. (496 aa) |
| | NDNF | Uncharacterized protein. (577 aa) |
| | NOS1 | Nitric oxide synthase 1. (1468 aa) |
| | SCAP | SREBF chaperone. (1360 aa) |
| | CAV1 | Caveolin 1. (303 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (471 aa) |
| | HSF1 | Heat shock transcription factor 1. (507 aa) |
| | P2RX2 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (496 aa) |
| | SLC8A1 | J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa) |
| | PPARD | Peroxisome proliferator-activated receptor delta isoform 1. (441 aa) |
| | CHRNA4 | Uncharacterized protein. (625 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (467 aa) |
| | LOXL2 | Lysyl oxidase-like protein 2. (774 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | WDR83 | Uncharacterized protein. (315 aa) |
| | KCNK2 | Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa) |
| | REST | RE1 silencing transcription factor. (1095 aa) |
| | NOTCH1 | Notch receptor 1. (2556 aa) |
| | SUV39H2 | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (410 aa) |
| | TM9SF4 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (665 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | KCNMA1 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] (1233 aa) |
| | AGER | Uncharacterized protein. (403 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (725 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (479 aa) |
| | SCFD1 | Sec1 family domain-containing protein 1 isoform a; Belongs to the STXBP/unc-18/SEC1 family. (641 aa) |
| | SRC | Tyrosine-protein kinase. (644 aa) |
| | LONP1 | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (961 aa) |
| | ATP6V1A | V-type proton ATPase catalytic subunit A. (617 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (370 aa) |
| | FAM167A | Family with sequence similarity 167 member A. (229 aa) |
| | RTN4 | Reticulon. (1193 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (735 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (770 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1206 aa) |
| | BNIP3 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (194 aa) |
| | CHRNA7 | Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin (By similarity). (502 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. (193 aa) |
| | KCNA5 | Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa) |
| | VCAM1 | Vascular cell adhesion molecule 1. (739 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (823 aa) |
| | ADAM15 | ADAM metallopeptidase domain 15. (919 aa) |
| | HSP90B1 | Endoplasmin. (804 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (314 aa) |
| | BNIP3L | BCL2 interacting protein 3 like. (223 aa) |
| | MT3 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa) |
| | SRF | Serum response factor. (508 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (291 aa) |
| | F7GWL3_MACMU | ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (188 aa) |
| | EDNRA | Uncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | MGARP | Mitochondria localized glutamic acid rich protein. (240 aa) |
| | ALKBH5 | Putative alpha-ketoglutarate-dependent dioxygenase ABH5. (394 aa) |
| | SLC2A4 | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (541 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | STOX1 | Storkhead box 1. (1119 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa) |
| | FOXO1 | Forkhead box O1. (655 aa) |
| | HYOU1 | Hypoxia up-regulated 1. (999 aa) |
| | TXNRD2 | Uncharacterized protein. (522 aa) |
| | ADA | Adenosine deaminase. (390 aa) |
| | PDK1 | Protein-serine/threonine kinase. (436 aa) |
| | LOC719678 | Uncharacterized protein. (626 aa) |
| | LMNA | Prelamin-A/C isoform 1; Belongs to the intermediate filament family. (663 aa) |
| | SLC2A8 | Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (516 aa) |
| | SLC11A2 | Solute carrier family 11 member 2. (597 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | PLEKHN1 | Pleckstrin homology domain containing N1. (622 aa) |
| | DDR2 | Discoidin domain receptor tyrosine kinase 2. (896 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (539 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2. (598 aa) |
| | CITED4 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (232 aa) |
| | ATP6V1G1 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | ENSMMUP00000043660 | Uncharacterized protein. (417 aa) |
| | ENSMMUP00000044881 | A_deaminase domain-containing protein. (74 aa) |
| | CCN2 | Cellular communication network factor 2. (349 aa) |
| | EGLN2 | Egl nine homolog 2. (405 aa) |
| | RORA | RAR related orphan receptor A. (555 aa) |
| | ATP6V0D1 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (372 aa) |
| | PDPN | Podoplanin. (162 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (344 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa) |
| | ERO1A | Endoplasmic reticulum oxidoreductase 1 alpha. (647 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | NKX3-1 | Homeobox protein Nkx-3.1. (232 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | BBC3 | BCL2 binding component 3. (261 aa) |
| | LOC721639 | Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (350 aa) |
| | NARF | Nuclear prelamin A recognition factor; Belongs to the NARF family. (493 aa) |
| | MMP2 | 72 kDa type IV collagenase isoform a preproprotein. (660 aa) |
| | UCP2 | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) |
| | GUCY1B1 | Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa) |
| | PINK1 | Serine/threonine-protein kinase PINK1, mitochondrial. (581 aa) |
| | EPAS1 | Endothelial PAS domain protein 1. (875 aa) |
| | SLC2A1 | MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (669 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) |
| | RBPJ | Uncharacterized protein. (500 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (274 aa) |
| | JUND | JunD proto-oncogene, AP-1 transcription factor subunit. (432 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa) |
| | NGB | Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes (By similarity). (151 aa) |
| | HIF1A | Hypoxia-inducible factor 1-alpha isoform 1. (826 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | AJUBA | Ajuba LIM protein. (538 aa) |
| | CBL | E3 ubiquitin-protein ligase CBL. (907 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (562 aa) |
| | P4HB | Protein disulfide-isomerase. (510 aa) |
| | CASR | Calcium sensing receptor. (1078 aa) |
| | VASN | Vasorin. (790 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | CYGB | GLOBIN domain-containing protein; Belongs to the globin family. (331 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (723 aa) |
| | P2RX3 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (468 aa) |
| | VHL | Von Hippel-Lindau disease tumor suppressor isoform 1. (213 aa) |
| | ANG | Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity). (146 aa) |
| | EDN1 | Preproendothelin-1. (211 aa) |
| | KCNK3 | Potassium channel subfamily K member. (394 aa) |
| | TXN2 | Thioredoxin domain-containing protein. (169 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (470 aa) |
| | NPEPPS | Aminopeptidase. (921 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (323 aa) |
| | DDIT4 | Uncharacterized protein. (261 aa) |
| | EEF2K | Eukaryotic elongation factor 2 kinase. (725 aa) |
| | ENSMMUP00000065445 | Uncharacterized protein. (230 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | CREBBP | CREB-binding protein isoform a. (2442 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | ADM | Adrenomedullin. (211 aa) |
| | NDUFS2 | Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (502 aa) |
| | FMN2 | Formin 2. (1833 aa) |
| | ENSMMUP00000067920 | Protein-serine/threonine kinase. (418 aa) |
| | SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa) |
| | BAD | Bcl2 antagonist of cell death. (167 aa) |
| | FABP1 | Fatty acid binding protein 1. (192 aa) |
| | ANGPTL4 | Angiopoietin like 4. (489 aa) |
| | ATF4 | BZIP domain-containing protein. (351 aa) |
| | HP1BP3 | Heterochromatin protein 1-binding protein 3. (553 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa) |
| | WTIP | WT1 interacting protein. (627 aa) |
| | BCL2 | BCL2 apoptosis regulator. (241 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | HMOX2 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (316 aa) |
| | CCND2 | Uncharacterized protein. (353 aa) |
| | TMEM199 | Transmembrane protein 199. (208 aa) |
| | UCN3 | Urocortin 3. (210 aa) |
| | NOL3 | Nucleolar protein 3. (206 aa) |
| | PAM | Peptidyl-glycine alpha-amidating monooxygenase isoform a preproprotein. (976 aa) |
| | FOS | V-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa) |
| | ABAT | 4-aminobutyrate aminotransferase. (568 aa) |
| | VHLL | VHL like. (181 aa) |
| | CYBA | Uncharacterized protein. (210 aa) |
| | ENSMMUP00000072696 | Uncharacterized protein. (103 aa) |
| | CA9 | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (447 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa) |
| | GUCY1A2 | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (733 aa) |
| | GATA6 | Transcription factor GATA-6. (595 aa) |
| | CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3. (769 aa) |
| | KCNMB1 | Calcium-activated potassium channel subunit beta-1. (191 aa) |
| | CYBB | Cytochrome b-245 beta chain. (617 aa) |
| | HK2 | Hexokinase 2. (917 aa) |
| | NPPC | C-type natriuretic peptide. (126 aa) |
| | LOC114674310 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (194 aa) |
| | BIRC2 | Baculoviral IAP repeat-containing protein 2. (618 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | ADO | 2-aminoethanethiol dioxygenase. (270 aa) |
| | GUCY1A1 | Guanylate cyclase soluble subunit alpha-3 isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa) |
| | SLC7A5 | Large neutral amino acids transporter small subunit 1. (507 aa) |
| | UCP3 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa) |
| | PDK3 | Protein-serine/threonine kinase. (415 aa) |
| | ENG | Endoglin. (672 aa) |
| | EP300 | Histone acetyltransferase p300. (2414 aa) |
| | EGLN2-2 | Fe2OG dioxygenase domain-containing protein. (527 aa) |
| | FUNDC1-2 | FUN14 domain-containing protein 1. (155 aa) |
| | AK4 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (260 aa) |
| | NFE2L2 | Nuclear factor erythroid 2-related factor 2 isoform 1. (606 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (545 aa) |
| | SIRT2 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa) |
| | CCDC115 | Coiled-coil domain containing 115. (209 aa) |
| | EGLN1 | Uncharacterized protein. (426 aa) |
| | LOC114672614 | Uncharacterized protein. (137 aa) |
| | SLC1A1 | Excitatory amino acid transporter 3. (524 aa) |
| | FAM162A | Family with sequence similarity 162 member A. (155 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (579 aa) |
| | CHRNB2 | Neuronal acetylcholine receptor subunit beta-2. (502 aa) |
| | CPEB4 | Cytoplasmic polyadenylation element-binding protein 4. (729 aa) |
