(17 nodes) Vocalization behavior network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CNTNAP2	Contactin associated protein like 2. (1331 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1730 aa)
	NEUROG1	Neurogenin 1. (237 aa)
	SRPX2	Sushi repeat containing protein X-linked 2. (465 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (2163 aa)
	NRXN3	Neurexin 3. (1571 aa)
	MYH14	Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2035 aa)
	AUTS2	Activator of transcription and developmental regulator AUTS2. (1225 aa)
	NRXN2	Neurexin 2. (1713 aa)
	NLGN3	Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity). (848 aa)
	NRXN1	Uncharacterized protein. (1547 aa)
	SHANK2	SH3 and multiple ankyrin repeat domains 2. (1846 aa)
	GLI3	GLI family zinc finger 3. (1580 aa)
	DLG4	Uncharacterized protein; Belongs to the MAGUK family. (972 aa)
	TIFAB	TIFA inhibitor. (204 aa)
	BRINP1	Deleted in bladder cancer protein 1. (761 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AUTS2	CNTNAP2	ENSMMUP00000023254	ENSMMUP00000020716	Activator of transcription and developmental regulator AUTS2.	Contactin associated protein like 2.	0.475
CNTNAP2	AUTS2	ENSMMUP00000020716	ENSMMUP00000023254	Contactin associated protein like 2.	Activator of transcription and developmental regulator AUTS2.	0.475
CNTNAP2	NLGN3	ENSMMUP00000020716	ENSMMUP00000045329	Contactin associated protein like 2.	Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).	0.833
CNTNAP2	NRXN1	ENSMMUP00000020716	ENSMMUP00000046829	Contactin associated protein like 2.	Uncharacterized protein.	0.438
CNTNAP2	SHANK1	ENSMMUP00000020716	ENSMMUP00000012256	Contactin associated protein like 2.	SH3 and multiple ankyrin repeat domains 1.	0.579
CNTNAP2	SHANK2	ENSMMUP00000020716	ENSMMUP00000061886	Contactin associated protein like 2.	SH3 and multiple ankyrin repeat domains 2.	0.620
CNTNAP2	SHANK3	ENSMMUP00000020716	ENSMMUP00000007390	Contactin associated protein like 2.	SH3 and multiple ankyrin repeat domains 3.	0.795
CNTNAP2	SRPX2	ENSMMUP00000020716	ENSMMUP00000010760	Contactin associated protein like 2.	Sushi repeat containing protein X-linked 2.	0.580
DLG4	NLGN3	ENSMMUP00000068361	ENSMMUP00000045329	Uncharacterized protein; Belongs to the MAGUK family.	Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).	0.811
DLG4	NRXN1	ENSMMUP00000068361	ENSMMUP00000046829	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein.	0.763
DLG4	NRXN2	ENSMMUP00000068361	ENSMMUP00000029746	Uncharacterized protein; Belongs to the MAGUK family.	Neurexin 2.	0.766
DLG4	NRXN3	ENSMMUP00000068361	ENSMMUP00000018193	Uncharacterized protein; Belongs to the MAGUK family.	Neurexin 3.	0.607
DLG4	SHANK1	ENSMMUP00000068361	ENSMMUP00000012256	Uncharacterized protein; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 1.	0.834
DLG4	SHANK2	ENSMMUP00000068361	ENSMMUP00000061886	Uncharacterized protein; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 2.	0.814
DLG4	SHANK3	ENSMMUP00000068361	ENSMMUP00000007390	Uncharacterized protein; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 3.	0.821
NLGN3	CNTNAP2	ENSMMUP00000045329	ENSMMUP00000020716	Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).	Contactin associated protein like 2.	0.833
NLGN3	DLG4	ENSMMUP00000045329	ENSMMUP00000068361	Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).	Uncharacterized protein; Belongs to the MAGUK family.	0.811
NLGN3	NRXN1	ENSMMUP00000045329	ENSMMUP00000046829	Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).	Uncharacterized protein.	0.999
NLGN3	NRXN2	ENSMMUP00000045329	ENSMMUP00000029746	Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).	Neurexin 2.	0.999
NLGN3	NRXN3	ENSMMUP00000045329	ENSMMUP00000018193	Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).	Neurexin 3.	0.916