STRINGSTRING
EDNRB EDNRB IRX3 IRX3 FMN1 FMN1 PKD1 PKD1 HNF1B HNF1B NPHS2 NPHS2 FOXC1 FOXC1 NOG NOG CALB1 CALB1 UMOD UMOD GATA3 GATA3 FGF2 FGF2 DCHS1 DCHS1 HS3ST3A1 HS3ST3A1 EXT1 EXT1 PKD2 PKD2 PAX2 PAX2 AHI1 AHI1 WT1 WT1 PBX1 PBX1 COMMD5 COMMD5 IQGAP1 IQGAP1 SMO SMO HS2ST1 HS2ST1 CD34 CD34 WNT1 WNT1 FGF8 FGF8 WNK4 WNK4 NOTCH1 NOTCH1 SALL1 SALL1 JAG1 JAG1 SMAD4 SMAD4 AQP11 AQP11 GDNF GDNF NPHS1 NPHS1 GREB1 GREB1 PTPRO PTPRO DLL1 DLL1 SIX2 SIX2 EDNRA EDNRA PROM1 PROM1 LGR4 LGR4 DLG1 DLG1 GREB1L GREB1L MEF2C MEF2C GPC3 GPC3 MTSS1 MTSS1 NOTCH2 NOTCH2 KIF26B KIF26B PTCH1 PTCH1 MAGI2 MAGI2 LAMB2 LAMB2 EYA1 EYA1 ASXL1 ASXL1 FOXD1 FOXD1 HOXD11 HOXD11 PGF PGF MYO1E MYO1E OSR1 OSR1 PECAM1 PECAM1 ENSMMUP00000062204 ENSMMUP00000062204 HES5 HES5 KLF15 KLF15 PODXL PODXL LZTS2 LZTS2 WNT11 WNT11 CTNNB1 CTNNB1 IRX1 IRX1 HOXA11 HOXA11 KLHL3 KLHL3 WNT6 WNT6 SHH SHH BMP2 BMP2 GLI3 GLI3 WNT4 WNT4 REX1BD REX1BD ADAMTS16 ADAMTS16 SOX8 SOX8 BCL2 BCL2 WNT9B WNT9B FOXJ1 FOXJ1 FGF1 FGF1 HEYL HEYL ENSMMUP00000072696 ENSMMUP00000072696 SOX9 SOX9 BASP1 BASP1 FOXC2 FOXC2 WNT7B WNT7B TCF21 TCF21 SIX1 SIX1 IRX2 IRX2 BMP4 BMP4 HS3ST3B1 HS3ST3B1 TFAP2B TFAP2B LOC114672614 LOC114672614 GZF1 GZF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (527 aa)
IRX3Iroquois homeobox 3. (501 aa)
FMN1Formin 1. (1425 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4298 aa)
HNF1BHepatocyte nuclear factor 1-beta. (557 aa)
NPHS2NPHS2 stomatin family member, podocin. (506 aa)
FOXC1Forkhead box C1. (551 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
CALB1Calbindin 1. (261 aa)
UMODUromodulin. (641 aa)
GATA3GATA binding protein 3. (444 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
DCHS1Dachsous cadherin-related 1. (3221 aa)
HS3ST3A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (406 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (969 aa)
PAX2Paired box 2. (418 aa)
AHI1Abelson helper integration site 1. (1196 aa)
WT1WT1 transcription factor. (517 aa)
PBX1Pre-B-cell leukemia transcription factor 1 isoform 1. (430 aa)
COMMD5COMM domain containing 5. (299 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1667 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
HS2ST1Heparan sulfate 2-O-sulfotransferase 1 isoform 1. (356 aa)
CD34CD34 molecule. (385 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
WNK4WNK lysine deficient protein kinase 4. (1242 aa)
NOTCH1Notch receptor 1. (2556 aa)
SALL1Spalt like transcription factor 1. (1324 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
GDNFGlial cell derived neurotrophic factor. (342 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1221 aa)
GREB1Growth regulating estrogen receptor binding 1. (1949 aa)
PTPROUncharacterized protein. (1216 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
SIX2SIX homeobox 2. (292 aa)
EDNRAUncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PROM1Prominin 1. (855 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (951 aa)
DLG1Disks large homolog 1 isoform 2; Belongs to the MAGUK family. (926 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1967 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform 1. (473 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa)
MTSS1MTSS I-BAR domain containing 1. (799 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform 1 preproprotein. (2471 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2107 aa)
PTCH1Patched 1. (1452 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1452 aa)
LAMB2Laminin subunit beta-2. (1798 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
ASXL1ASXL transcriptional regulator 1. (1541 aa)
FOXD1Forkhead box D1. (468 aa)
HOXD11Homeobox D11. (338 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
MYO1EMyosin-Ie; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (834 aa)
ENSMMUP00000062204Uncharacterized protein. (81 aa)
HES5Uncharacterized protein. (166 aa)
KLF15Krueppel-like factor 15. (416 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (522 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
CTNNB1Catenin beta-1. (781 aa)
IRX1Iroquois homeobox 1. (480 aa)
HOXA11Homeobox A11. (311 aa)
KLHL3BTB domain-containing protein. (612 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
GLI3GLI family zinc finger 3. (1580 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
REX1BDUncharacterized protein. (657 aa)
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (1275 aa)
SOX8SRY-box transcription factor 8. (617 aa)
BCL2BCL2 apoptosis regulator. (241 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
FOXJ1Forkhead box J1. (421 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (477 aa)
ENSMMUP00000072696Uncharacterized protein. (103 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
BASP1Brain acid soluble protein 1. (227 aa)
FOXC2Forkhead box C2. (471 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
TCF21Transcription factor 21. (179 aa)
SIX1SIX homeobox 1. (284 aa)
IRX2Iroquois homeobox 2. (500 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
HS3ST3B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (390 aa)
TFAP2BTranscription factor AP-2 beta. (504 aa)
LOC114672614Uncharacterized protein. (137 aa)
GZF1GDNF inducible zinc finger protein 1. (819 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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