STRINGSTRING
ETV6 ETV6 ELL3 ELL3 XRCC5 XRCC5 CTC1 CTC1 MECOM MECOM SCRG1 SCRG1 YAP1 YAP1 BYSL BYSL TRIM71 TRIM71 NF1 NF1 BRCA2 BRCA2 WNT2B WNT2B TP53 TP53 SHB SHB FGF9 FGF9 YJEFN3 YJEFN3 PBX1 PBX1 RARG RARG OVOL1 OVOL1 KDR KDR SFN SFN ID4 ID4 CD34 CD34 WNT1 WNT1 CEP120 CEP120 FGF8 FGF8 SFRP2 SFRP2 SNAI2 SNAI2 CD109 CD109 CDKN2C CDKN2C IFT20 IFT20 WNT3 WNT3 IRS2 IRS2 IRF6 IRF6 OSR2 OSR2 TGFB1 TGFB1 SIX2 SIX2 RNF43 RNF43 TBX3 TBX3 TP63 TP63 NES NES ERCC2 ERCC2 SART3 SART3 RARB RARB OPRD1 OPRD1 PTCH1 PTCH1 NFIB NFIB FGF10 FGF10 TIAL1 TIAL1 WNT10B WNT10B PRRX1 PRRX1 ENSMMUP00000062234 ENSMMUP00000062234 WNT11 WNT11 CTNNB1 CTNNB1 SHOX2 SHOX2 ARIH2 ARIH2 SHH SHH BABAM1 BABAM1 GLI3 GLI3 KDF1 KDF1 LIG4 LIG4 FGF4 FGF4 HOXB4 HOXB4 NR2E1 NR2E1 RUNX2 RUNX2 HOXA3 HOXA3 WNT5A WNT5A RUNX1 RUNX1 WNT7B WNT7B AXIN2 AXIN2 HMX2 HMX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ETV6Uncharacterized protein. (457 aa)
ELL3Elongation factor for RNA polymerase II 3. (399 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
CTC1CST telomere replication complex component 1. (1267 aa)
MECOMMDS1 and EVI1 complex locus. (1124 aa)
SCRG1Stimulator of chondrogenesis 1. (98 aa)
YAP1Yes associated protein 1. (508 aa)
BYSLBystin like. (440 aa)
TRIM71Tripartite motif containing 71. (868 aa)
NF1Neurofibromin 1. (2867 aa)
BRCA2BRCA2 DNA repair associated. (3377 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (433 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
YJEFN3YjeF N-terminal domain containing 3. (299 aa)
PBX1Pre-B-cell leukemia transcription factor 1 isoform 1. (430 aa)
RARGRetinoic acid receptor gamma. (454 aa)
OVOL1Uncharacterized protein. (267 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
ID4DNA-binding protein inhibitor ID-4. (161 aa)
CD34CD34 molecule. (385 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
CEP120Centrosomal protein of 120 kDa isoform 1. (986 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SFRP2Secreted frizzled-related protein 2. (295 aa)
SNAI2Protein snail-like protein 2. (268 aa)
CD109CD109 molecule. (1364 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (168 aa)
IFT20Intraflagellar transport protein 20-like protein. (158 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
IRS2Insulin receptor substrate 2. (1394 aa)
IRF6Interferon regulatory factor 6 isoform 1. (467 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SIX2SIX homeobox 2. (292 aa)
RNF43RING-type domain-containing protein. (783 aa)
TBX3T-box transcription factor 3. (743 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
NESNestin; Belongs to the intermediate filament family. (1721 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
SART3Uncharacterized protein. (1009 aa)
RARBRetinoic acid receptor beta. (448 aa)
OPRD1YTH N6-methyladenosine RNA binding protein 2. (589 aa)
PTCH1Patched 1. (1452 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (566 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (375 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
PRRX1Uncharacterized protein. (245 aa)
ENSMMUP00000062234RBR-type E3 ubiquitin transferase. (228 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
CTNNB1Catenin beta-1. (781 aa)
SHOX2Short stature homeobox 2. (355 aa)
ARIH2RBR-type E3 ubiquitin transferase. (470 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
BABAM1BRISC and BRCA1-A complex member 1. (329 aa)
GLI3GLI family zinc finger 3. (1580 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
LIG4DNA ligase. (911 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
HOXB4Homeobox B4. (251 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (390 aa)
RUNX2RUNX family transcription factor 2. (647 aa)
HOXA3Homeobox A3. (443 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (462 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
AXIN2Axin 2. (862 aa)
HMX2Homeobox domain-containing protein. (273 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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