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| | TSC1 | TSC complex subunit 1. (1164 aa) |
| | OPA1 | OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1071 aa) |
| | PAX2 | Paired box 2. (418 aa) |
| | IFT57 | Intraflagellar transport 57. (439 aa) |
| | MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (697 aa) |
| | SEMA4C | Uncharacterized protein; Belongs to the semaphorin family. (833 aa) |
| | CLUAP1 | Clusterin associated protein 1. (445 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | CECR2 | CECR2 histone acetyl-lysine reader. (1463 aa) |
| | DVL3 | Segment polarity protein dishevelled homolog DVL-3. (716 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (233 aa) |
| | SHANK3 | SH3 and multiple ankyrin repeat domains 3. (1730 aa) |
| | TRIM71 | Tripartite motif containing 71. (868 aa) |
| | GRHL3 | Grainyhead like transcription factor 3. (626 aa) |
| | SUFU | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (500 aa) |
| | TEAD4 | TUB like protein 3; Belongs to the TUB family. (728 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | SALL4 | Spalt like transcription factor 4. (1053 aa) |
| | LHX2 | LIM/homeobox protein Lhx2. (406 aa) |
| | HNF1B | Hepatocyte nuclear factor 1-beta. (557 aa) |
| | PLXNB2 | Plexin B2. (1844 aa) |
| | KDM6A | Lysine demethylase 6A. (1489 aa) |
| | TSC2 | TSC complex subunit 2. (2057 aa) |
| | IRX3 | Iroquois homeobox 3. (501 aa) |
| | IFT52 | Intraflagellar transport protein 52 homolog. (437 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (767 aa) |
| | HES5 | Uncharacterized protein. (166 aa) |
| | PODXL | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (522 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | IRX1 | Iroquois homeobox 1. (480 aa) |
| | SHROOM3 | Shroom family member 3. (2002 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | MIB1 | Mindbomb E3 ubiquitin protein ligase 1. (1006 aa) |
| | FZD3 | Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | HECTD1 | E3 ubiquitin-protein ligase HECTD1. (2610 aa) |
| | ADM | Adrenomedullin. (211 aa) |
| | TMED2 | GOLD domain-containing protein. (208 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | RALA | Ras-related protein Ral-A. (206 aa) |
| | PROX1 | Prospero homeobox protein 1. (737 aa) |
| | SOX8 | SRY-box transcription factor 8. (617 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa) |
| | SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa) |
| | STIL | STIL centriolar assembly protein. (1287 aa) |
| | SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa) |
| | LMO4 | LIM domain only 4. (224 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (462 aa) |
| | TEAD2 | TEA domain transcription factor 2. (451 aa) |
| | SIX1 | SIX homeobox 1. (284 aa) |
| | IRX2 | Iroquois homeobox 2. (500 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | OVOL2 | Transcription factor Ovo-like 2. (275 aa) |
| | SPINT1 | Serine peptidase inhibitor, Kunitz type 1. (667 aa) |
| | LRP2 | LDL receptor related protein 2. (4660 aa) |
| | GDF7 | Growth differentiation factor 7. (539 aa) |
| | SKI | SKI proto-oncogene. (730 aa) |
| | HAND1 | Heart and neural crest derivatives expressed 1. (215 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) |
| | FUZ | Fuzzy planar cell polarity protein. (445 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | RPS7 | 40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa) |
| | MKS1 | MKS transition zone complex subunit 1. (559 aa) |
| | RARA | Retinoic acid receptor alpha isoform 1. (462 aa) |
| | RARG | Retinoic acid receptor gamma. (454 aa) |
| | LOC703060 | WD_REPEATS_REGION domain-containing protein. (1237 aa) |
| | STK4 | Serine/threonine-protein kinase 4 18kDa subunit; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regul [...] (487 aa) |
| | KIF20B | Kinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1822 aa) |
| | BBS4 | Bardet-Biedl syndrome 4 protein. (519 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa) |
| | HS2ST1 | Heparan sulfate 2-O-sulfotransferase 1 isoform 1. (356 aa) |
| | SOX4 | Transcription factor SOX. (467 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa) |
| | DLC1 | DLC1 Rho GTPase activating protein. (1528 aa) |
| | RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | SFRP2 | Secreted frizzled-related protein 2. (295 aa) |
| | CEP290 | Centrosomal protein 290. (2480 aa) |
| | TRAF6 | TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa) |
| | GDNF | Glial cell derived neurotrophic factor. (342 aa) |
| | PHACTR4 | Phosphatase and actin regulator. (817 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (243 aa) |
| | MTHFD1L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (976 aa) |
| | VANGL2 | Vang-like protein. (521 aa) |
| | CELSR1 | Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (1818 aa) |
| | GRHL2 | Grainyhead like transcription factor 2. (625 aa) |
| | SETD2 | SET domain containing 2, histone lysine methyltransferase. (2565 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1206 aa) |
| | NODAL | Nodal growth differentiation factor. (347 aa) |
| | SEC24B | SEC24 homolog B, COPII coat complex component. (1277 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | VASP | Vasodilator stimulated phosphoprotein. (428 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (314 aa) |
| | TBXT | T-box transcription factor T. (430 aa) |
| | PTK7 | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa) |
| | BRD2 | Bromodomain containing 2. (815 aa) |
| | CC2D2A | Coiled-coil and C2 domain containing 2A. (1620 aa) |
| | DEAF1 | DEAF1 transcription factor. (615 aa) |
| | KDM2B | Lysine demethylase 2B. (1340 aa) |
| | PRICKLE1 | Prickle planar cell polarity protein 1. (848 aa) |
| | F6UCW2_MACMU | 40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa) |
| | ST14 | Suppression of tumorigenicity 14. (962 aa) |
| | CITED4 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (232 aa) |
| | LUZP1 | Leucine zipper protein 1. (1075 aa) |
| | STK3 | Uncharacterized protein. (519 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (695 aa) |
| | MTHFD1 | Uncharacterized protein. (1140 aa) |
| | SCRIB | Scribble planar cell polarity protein. (1451 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (841 aa) |
| | MED12 | Mediator complex subunit 12. (2178 aa) |
| | GLMN | Glomulin, FKBP associated protein. (594 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | ARHGAP35 | Rho GTPase activating protein 35. (1499 aa) |
| | IFT172 | Intraflagellar transport protein 172 homolog. (1749 aa) |
| | PTCH1 | Patched 1. (1452 aa) |
| | COBL | Cordon-bleu WH2 repeat protein. (1395 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | LRRC1 | Leucine-rich repeat-containing protein 1. (524 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | HESX1 | HESX homeobox 1. (185 aa) |
| | TCTN1 | Tectonic family member 1. (603 aa) |
| | SOX11 | Transcription factor SOX. (441 aa) |
| | HIF1A | Hypoxia-inducible factor 1-alpha isoform 1. (826 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (576 aa) |
| | OSR1 | Odd-skipped related transcription factor 1. (266 aa) |
