(11 nodes) Nephric duct morphogenesis network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EFNB2	Ephrin B2; Belongs to the ephrin family. (333 aa)
	EPHA7	EPH receptor A7. (998 aa)
	AHI1	Abelson helper integration site 1. (1196 aa)
	PAX2	Paired box 2. (418 aa)
	GATA3	GATA binding protein 3. (444 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
	OSR1	Odd-skipped related transcription factor 1. (266 aa)
	HNF1B	Hepatocyte nuclear factor 1-beta. (557 aa)
	EPHA4	EPH receptor A4. (1008 aa)
	GPC3	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	GATA3	ENSMMUP00000077296	ENSMMUP00000009115	Bone morphogenetic protein 4.	GATA binding protein 3.	0.418
BMP4	GPC3	ENSMMUP00000077296	ENSMMUP00000045159	Bone morphogenetic protein 4.	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.408
BMP4	PAX2	ENSMMUP00000077296	ENSMMUP00000012018	Bone morphogenetic protein 4.	Paired box 2.	0.400
EFNB2	EPHA4	ENSMMUP00000036048	ENSMMUP00000048736	Ephrin B2; Belongs to the ephrin family.	EPH receptor A4.	0.985
EFNB2	EPHA7	ENSMMUP00000036048	ENSMMUP00000019514	Ephrin B2; Belongs to the ephrin family.	EPH receptor A7.	0.738
EPHA4	EFNB2	ENSMMUP00000048736	ENSMMUP00000036048	EPH receptor A4.	Ephrin B2; Belongs to the ephrin family.	0.985
EPHA7	EFNB2	ENSMMUP00000019514	ENSMMUP00000036048	EPH receptor A7.	Ephrin B2; Belongs to the ephrin family.	0.738
GATA3	BMP4	ENSMMUP00000009115	ENSMMUP00000077296	GATA binding protein 3.	Bone morphogenetic protein 4.	0.418
GPC3	BMP4	ENSMMUP00000045159	ENSMMUP00000077296	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Bone morphogenetic protein 4.	0.408
GPC3	WNT9B	ENSMMUP00000045159	ENSMMUP00000070542	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.911
OSR1	PAX2	ENSMMUP00000058804	ENSMMUP00000012018	Odd-skipped related transcription factor 1.	Paired box 2.	0.431
PAX2	BMP4	ENSMMUP00000012018	ENSMMUP00000077296	Paired box 2.	Bone morphogenetic protein 4.	0.400
PAX2	OSR1	ENSMMUP00000012018	ENSMMUP00000058804	Paired box 2.	Odd-skipped related transcription factor 1.	0.431
WNT9B	GPC3	ENSMMUP00000070542	ENSMMUP00000045159	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.911