(13 nodes) Ureter development network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAX2	Paired box 2. (418 aa)
	GATA3	GATA binding protein 3. (444 aa)
	LZTS2	Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa)
	OSR1	Odd-skipped related transcription factor 1. (266 aa)
	ALDH1A2	Retinal dehydrogenase 2 isoform 1; Belongs to the aldehyde dehydrogenase family. (518 aa)
	RET	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
	EMX2	Homeobox protein EMX2 isoform 1. (252 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	SOX8	SRY-box transcription factor 8. (617 aa)
	SOX17	SRY-box transcription factor 17. (414 aa)
	FOXF1	Forkhead box F1. (432 aa)
	NFIA	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (554 aa)
	TBX18	T-box transcription factor 18. (556 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	FOXF1	ENSMMUP00000077296	ENSMMUP00000063792	Bone morphogenetic protein 4.	Forkhead box F1.	0.622
BMP4	GATA3	ENSMMUP00000077296	ENSMMUP00000009115	Bone morphogenetic protein 4.	GATA binding protein 3.	0.418
BMP4	PAX2	ENSMMUP00000077296	ENSMMUP00000012018	Bone morphogenetic protein 4.	Paired box 2.	0.400
BMP4	SOX17	ENSMMUP00000077296	ENSMMUP00000066931	Bone morphogenetic protein 4.	SRY-box transcription factor 17.	0.723
FOXF1	BMP4	ENSMMUP00000063792	ENSMMUP00000077296	Forkhead box F1.	Bone morphogenetic protein 4.	0.622
GATA3	BMP4	ENSMMUP00000009115	ENSMMUP00000077296	GATA binding protein 3.	Bone morphogenetic protein 4.	0.418
GATA3	SOX17	ENSMMUP00000009115	ENSMMUP00000066931	GATA binding protein 3.	SRY-box transcription factor 17.	0.603
OSR1	PAX2	ENSMMUP00000058804	ENSMMUP00000012018	Odd-skipped related transcription factor 1.	Paired box 2.	0.431
PAX2	BMP4	ENSMMUP00000012018	ENSMMUP00000077296	Paired box 2.	Bone morphogenetic protein 4.	0.400
PAX2	OSR1	ENSMMUP00000012018	ENSMMUP00000058804	Paired box 2.	Odd-skipped related transcription factor 1.	0.431
SOX17	BMP4	ENSMMUP00000066931	ENSMMUP00000077296	SRY-box transcription factor 17.	Bone morphogenetic protein 4.	0.723
SOX17	GATA3	ENSMMUP00000066931	ENSMMUP00000009115	SRY-box transcription factor 17.	GATA binding protein 3.	0.603