14 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANK2	Ankyrin 2. (4045 aa)
	KCNE3	Uncharacterized protein. (103 aa)
	KCNJ8	Potassium voltage-gated channel subfamily J member 8. (424 aa)
	KCNE5	Potassium voltage-gated channel subfamily E regulatory subunit 5. (142 aa)
	KCNE2	Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
	SCN2B	Sodium voltage-gated channel beta subunit 2. (215 aa)
	KCNJ5	Potassium voltage-gated channel subfamily J member 5. (469 aa)
	KCNH2	Potassium voltage-gated channel subfamily H member 2. (1159 aa)
	SCN5A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
	KCNJ3	G protein-activated inward rectifier potassium channel 1. (501 aa)
	KCNE4	Potassium voltage-gated channel subfamily E regulatory subunit 4. (170 aa)
	RYR2	Ryanodine receptor 2. (4967 aa)
	PKP2	Plakophilin 2. (790 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANK2	KCNE2	ENSMMUP00000034873	ENSMMUP00000076053	Ankyrin 2.	Potassium voltage-gated channel subfamily E regulatory subunit 2.	0.440
ANK2	SCN5A	ENSMMUP00000034873	ENSMMUP00000020800	Ankyrin 2.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.529
KCNE2	ANK2	ENSMMUP00000076053	ENSMMUP00000034873	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Ankyrin 2.	0.440
KCNE2	KCNE3	ENSMMUP00000076053	ENSMMUP00000080102	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Uncharacterized protein.	0.822
KCNE2	KCNE4	ENSMMUP00000076053	ENSMMUP00000001466	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily E regulatory subunit 4.	0.843
KCNE2	KCNE5	ENSMMUP00000076053	ENSMMUP00000076318	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily E regulatory subunit 5.	0.753
KCNE2	KCNH2	ENSMMUP00000076053	ENSMMUP00000026900	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily H member 2.	0.888
KCNE2	KCNJ5	ENSMMUP00000076053	ENSMMUP00000064599	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily J member 5.	0.551
KCNE2	KCNJ8	ENSMMUP00000076053	ENSMMUP00000078512	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily J member 8.	0.497
KCNE2	KCNQ1	ENSMMUP00000076053	ENSMMUP00000010172	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.990
KCNE2	RYR2	ENSMMUP00000076053	ENSMMUP00000001421	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Ryanodine receptor 2.	0.453
KCNE2	SCN5A	ENSMMUP00000076053	ENSMMUP00000020800	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.800
KCNE3	KCNE2	ENSMMUP00000080102	ENSMMUP00000076053	Uncharacterized protein.	Potassium voltage-gated channel subfamily E regulatory subunit 2.	0.822
KCNE3	KCNE4	ENSMMUP00000080102	ENSMMUP00000001466	Uncharacterized protein.	Potassium voltage-gated channel subfamily E regulatory subunit 4.	0.734
KCNE3	KCNE5	ENSMMUP00000080102	ENSMMUP00000076318	Uncharacterized protein.	Potassium voltage-gated channel subfamily E regulatory subunit 5.	0.584
KCNE3	KCNH2	ENSMMUP00000080102	ENSMMUP00000026900	Uncharacterized protein.	Potassium voltage-gated channel subfamily H member 2.	0.661
KCNE3	KCNJ5	ENSMMUP00000080102	ENSMMUP00000064599	Uncharacterized protein.	Potassium voltage-gated channel subfamily J member 5.	0.622
KCNE3	KCNJ8	ENSMMUP00000080102	ENSMMUP00000078512	Uncharacterized protein.	Potassium voltage-gated channel subfamily J member 8.	0.533
KCNE3	KCNQ1	ENSMMUP00000080102	ENSMMUP00000010172	Uncharacterized protein.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.996
KCNE3	SCN2B	ENSMMUP00000080102	ENSMMUP00000065378	Uncharacterized protein.	Sodium voltage-gated channel beta subunit 2.	0.513