STRINGSTRING
EDN3 EDN3 OOEP OOEP DBF4B DBF4B PCID2 PCID2 UBXN2B UBXN2B MAPK15 MAPK15 SLF1 SLF1 CDC23 CDC23 IGF1 IGF1 RDX RDX EPGN EPGN STRA8 STRA8 USP19 USP19 TAS1R2 TAS1R2 AURKB AURKB DLGAP5 DLGAP5 PRDM9 PRDM9 SASS6 SASS6 KIF14 KIF14 PLCB1 PLCB1 THOC1 THOC1 NEUROG1 NEUROG1 CENPV CENPV F7DC82_MACMU F7DC82_MACMU PLCG2 PLCG2 PAF1 PAF1 GIPC1 GIPC1 CDC14B CDC14B SPAG5 SPAG5 H2AFY H2AFY KLHL18 KLHL18 FEN1 FEN1 RPTOR RPTOR DBF4 DBF4 TFDP1 TFDP1 SMC5 SMC5 CDC25C CDC25C CRNN CRNN CUL4B CUL4B RAD51C RAD51C SIN3A SIN3A CXCR5 CXCR5 EGF EGF GPSM2 GPSM2 DTL DTL MAP3K20 MAP3K20 EIF4G1 EIF4G1 TERT TERT ANKRD31 ANKRD31 PBX1 PBX1 PDGFRB PDGFRB RGCC RGCC PKP4 PKP4 H9H3J4_MACMU H9H3J4_MACMU IGF1R IGF1R NCAPH2 NCAPH2 NUSAP1 NUSAP1 MEPCE MEPCE PPP1R35 PPP1R35 ANAPC11 ANAPC11 KIF3B KIF3B ADAM17 ADAM17 UBE2E2 UBE2E2 ADAMTS1 ADAMTS1 HOXA13 HOXA13 KIF20B KIF20B NCAPG2 NCAPG2 CDT1 CDT1 MDM2 MDM2 DRD2 DRD2 APP APP CSPP1 CSPP1 PRKCE PRKCE RAD51AP1 RAD51AP1 CEP120 CEP120 FGF8 FGF8 NPM1 NPM1 RAD51B RAD51B NSFL1C NSFL1C PBK PBK NRM NRM SMC4 SMC4 LSM10 LSM10 CDC27 CDC27 CDCA5 CDCA5 NDC80 NDC80 SFPQ SFPQ CUL4A CUL4A WIZ WIZ SMPD3 SMPD3 KAT5 KAT5 CIT CIT SMC2 SMC2 RRM2B RRM2B CDC25A CDC25A BRD4 BRD4 ESPL1 ESPL1 GLI1 GLI1 ATRX ATRX KMT2E KMT2E E2F7 E2F7 KCNA5 KCNA5 DRD3 DRD3 CDK4 CDK4 TGFB1 TGFB1 NUP62 NUP62 XRCC3 XRCC3 CCNB1 CCNB1 CDK1 CDK1 STOX1 STOX1 CDC16 CDC16 ROCK2 ROCK2 CEP295 CEP295 CHEK2 CHEK2 CUL3 CUL3 HNRNPU HNRNPU LRP5 LRP5 AURKA AURKA TP63 TP63 ECT2 ECT2 DDX11 DDX11 CDC42 CDC42 CENPVL3 CENPVL3 DDR2 DDR2 CDC25B CDC25B SLF2 SLF2 DDX3X DDX3X PIWIL2 PIWIL2 CCND3 CCND3 POLDIP2 POLDIP2 LEF1 LEF1 SPHK1 SPHK1 CENPJ CENPJ CCN2 CCN2 RRM1 RRM1 INSR INSR RHOA RHOA PRAP1 PRAP1 TGFA TGFA EGFR EGFR BIRC5 BIRC5 PLK4 PLK4 CDC14C CDC14C CPSF3 CPSF3 ENSMMUP00000048641 ENSMMUP00000048641 RB1 RB1 BHMG1 BHMG1 DDX39B DDX39B ATAD5 ATAD5 MTA3 MTA3 TBX2 TBX2 PKN2 PKN2 FGF10 FGF10 ENSMMUP00000053583 ENSMMUP00000053583 SSTR5 SSTR5 PLRG1 PLRG1 FAM178B FAM178B STXBP4 STXBP4 DYNC1LI1 DYNC1LI1 MECP2 MECP2 KIF23 KIF23 THOC5 THOC5 LOC715778 LOC715778 ANKRD17 ANKRD17 WNT10B WNT10B RRM2 RRM2 MBLAC1 MBLAC1 RANBP1 RANBP1 EZH2 EZH2 NCAPG NCAPG DDX3Y DDX3Y KAT2B KAT2B RHNO1 RHNO1 AKT1 AKT1 ENSMMUP00000061681 ENSMMUP00000061681 ENSMMUP00000061990 ENSMMUP00000061990 MAD2L1BP MAD2L1BP MED1 MED1 EDN1 EDN1 PAGR1 PAGR1 ANXA1 ANXA1 CDC7 CDC7 DDRGK1 DDRGK1 CDC14A CDC14A CDC6 CDC6 CD28 CD28 MAD1L1 MAD1L1 PDGFB PDGFB LOC717718 LOC717718 PHOX2B PHOX2B PPP1R10 PPP1R10 TPR TPR ENSMMUP00000067677 ENSMMUP00000067677 DYNC1H1 DYNC1H1 NSMCE2 NSMCE2 WNT4 WNT4 TMOD3 TMOD3 SVIL SVIL MAD2L1 MAD2L1 GIPC3 GIPC3 NUMA1 NUMA1 SMPD5 SMPD5 INO80 INO80 STIL STIL ANAPC7 ANAPC7 DYRK3 DYRK3 NCAPH NCAPH INCENP INCENP CDC73 CDC73 ENSMMUP00000072883 ENSMMUP00000072883 RCC2 RCC2 WNT5A WNT5A AIF1 AIF1 RACGAP1 RACGAP1 IGF2 IGF2 RAD21 RAD21 FBXO42 FBXO42 E2F8 E2F8 ZNF16 ZNF16 BTC BTC ENSMMUP00000077290 ENSMMUP00000077290 PHIP PHIP MSX1 MSX1 SOX15 SOX15 SIRT2 SIRT2 LSM11 LSM11 ENSMMUP00000078666 ENSMMUP00000078666 GIPC2 GIPC2 IL1B IL1B CDK10 CDK10 GEN1 GEN1 CCND1 CCND1 MTBP MTBP EREG EREG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDN3Endothelin 3. (257 aa)
OOEPOocyte expressed protein. (149 aa)
DBF4BDBF4 zinc finger B. (684 aa)
PCID2PCI domain containing 2. (453 aa)
UBXN2BUBX domain-containing protein 2B. (331 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1059 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
IGF1Insulin like growth factor 1. (208 aa)
RDXRadixin. (604 aa)
EPGNEpithelial mitogen. (154 aa)
STRA8Stimulated by retinoic acid 8. (369 aa)
USP19Ubiquitin specific peptidase 19. (1372 aa)
TAS1R2Taste receptor type 1 member 2; Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners (By similarity). (839 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
DLGAP5DLG associated protein 5. (850 aa)
PRDM9Uncharacterized protein. (482 aa)
SASS6SAS-6 centriolar assembly protein. (656 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1649 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
THOC1THO complex subunit 1. (657 aa)
NEUROG1Neurogenin 1. (237 aa)
CENPVCentromere protein V. (274 aa)
F7DC82_MACMUUncharacterized protein. (293 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
GIPC1PDZ domain-containing protein GIPC1 isoform 1. (333 aa)
CDC14BCell division cycle 14B. (498 aa)
SPAG5Sperm associated antigen 5. (1195 aa)
H2AFYCore histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)
KLHL18Kelch like family member 18. (574 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
DBF4Protein DBF4 homolog A. (675 aa)
TFDP1Transcription factor. (410 aa)
SMC5SMC_N domain-containing protein. (1201 aa)
CDC25CCell division cycle 25C. (507 aa)
CRNNCornulin. (494 aa)
CUL4BCullin 4B; Belongs to the cullin family. (933 aa)
RAD51CRAD51 paralog C. (367 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1213 aa)
GPSM2G-protein-signaling modulator 2. (686 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase MLT isoform 1. (800 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1 isoform 6. (1604 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1130 aa)
ANKRD31Ankyrin repeat domain 31. (1875 aa)
PBX1Pre-B-cell leukemia transcription factor 1 isoform 1. (430 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
RGCCUncharacterized protein. (162 aa)
PKP4Plakophilin-4 isoform a. (1192 aa)
H9H3J4_MACMUUncharacterized protein. (142 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
NCAPH2Condensin-2 complex subunit H2 isoform 2. (611 aa)
NUSAP1Nucleolar and spindle associated protein 1. (423 aa)
MEPCEMethylphosphate capping enzyme. (689 aa)
PPP1R35Protein phosphatase 1 regulatory subunit 35. (252 aa)
ANAPC11Uncharacterized protein. (192 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
ADAM17Disintegrin and metalloproteinase domain-containing protein 17 preproprotein. (824 aa)
UBE2E2Ubiquitin-conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
ADAMTS1A disintegrin and metalloproteinase with thrombospondin motifs 1 preproprotein. (967 aa)
HOXA13Homeobox A13. (226 aa)
KIF20BKinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1822 aa)
NCAPG2Uncharacterized protein. (1143 aa)
CDT1Chromatin licensing and DNA replication factor 1. (551 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
APPAmyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] (751 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1297 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
RAD51AP1RAD51 associated protein 1. (352 aa)
CEP120Centrosomal protein of 120 kDa isoform 1. (986 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
NPM1Nucleophosmin isoform 1. (294 aa)
RAD51BRAD51 paralog B. (424 aa)
NSFL1CUncharacterized protein. (372 aa)
PBKPDZ binding kinase. (323 aa)
NRMNurim. (262 aa)
SMC4Structural maintenance of chromosomes protein. (1287 aa)
LSM10U7 snRNA-associated Sm-like protein LSm10. (123 aa)
CDC27Cell division cycle protein 27 homolog isoform 1. (830 aa)
CDCA5Cell division cycle associated 5. (252 aa)
NDC80Kinetochore protein NDC80 homolog. (642 aa)
SFPQSplicing factor, proline-and glutamine-rich. (707 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
WIZWIZ zinc finger. (968 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa)
CITCitron rho-interacting serine/threonine kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2132 aa)
SMC2Structural maintenance of chromosomes protein. (1170 aa)
RRM2BRibonucleotide reductase regulatory TP53 inducible subunit M2B. (351 aa)
CDC25AM-phase inducer phosphatase 1 isoform a. (524 aa)
BRD4Bromodomain containing 4. (1334 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2120 aa)
GLI1Zinc finger protein GLI1 isoform 1. (1106 aa)
ATRXATRX chromatin remodeler. (2490 aa)
KMT2EHistone-lysine N-methyltransferase MLL5. (1859 aa)
E2F7E2F transcription factor 7. (910 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
DRD3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (400 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
NUP62Nuclear pore glycoprotein p62. (521 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (346 aa)
CCNB1G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
STOX1Storkhead box 1. (1119 aa)
CDC16Cell division cycle protein 16 homolog. (620 aa)
ROCK2Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
CEP295Centrosomal protein 295. (2601 aa)
CHEK2Checkpoint kinase 2. (539 aa)
CUL3Cullin-3; Belongs to the cullin family. (768 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1612 aa)
AURKASerine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (403 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ECT2Epithelial cell transforming 2. (958 aa)
DDX11DEAD/H-box helicase 11. (970 aa)
CDC42Cell division control protein 42 homolog isoform 1. (191 aa)
CENPVL3GFA domain-containing protein. (287 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (896 aa)
CDC25BCell division cycle 25B. (570 aa)
SLF2Uncharacterized protein. (1187 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa)
PIWIL2Piwi like-2 protein; Belongs to the argonaute family. (973 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (315 aa)
POLDIP2ApaG domain-containing protein. (374 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
SPHK1Sphingosine kinase 1. (470 aa)
CENPJCentromere protein J. (1338 aa)
CCN2Cellular communication network factor 2. (349 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
INSRInsulin receptor subunit alpha; Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src-homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosine residues, including the p85 regulatory subunit of PI3K and SHP2. Phosphorylation of IRSs proteins lea [...] (1279 aa)
RHOARas homolog family member A. (209 aa)
PRAP1Uncharacterized protein. (149 aa)
TGFAProtransforming growth factor alpha; TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. (166 aa)
EGFREpidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa)
BIRC5Baculoviral IAP repeat-containing protein 5 isoform 1. (142 aa)
PLK4Polo like kinase 4. (970 aa)
CDC14CCell division cycle 14C. (463 aa)
CPSF3Cleavage and polyadenylation specificity factor subunit 3. (684 aa)
ENSMMUP00000048641Uncharacterized protein. (258 aa)
RB1Retinoblastoma-associated protein. (928 aa)
BHMG1Basic helix-loop-helix and HMG-box containing 1. (642 aa)
DDX39BSpliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (428 aa)
ATAD5ATPase family AAA domain containing 5. (1848 aa)
MTA3Metastasis associated 1 family member 3. (621 aa)
TBX2T-box transcription factor 2. (712 aa)
PKN2Protein kinase N2. (981 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSMMUP00000053583HORMA domain-containing protein. (205 aa)
SSTR5Somatostatin receptor 5; Belongs to the G-protein coupled receptor 1 family. (364 aa)
PLRG1Pleiotropic regulator 1 isoform 1. (514 aa)
FAM178BFamily with sequence similarity 178 member B. (679 aa)
STXBP4Syntaxin-binding protein 4. (554 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (974 aa)
THOC5THO complex 5. (694 aa)
LOC715778Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (233 aa)
ANKRD17Ankyrin repeat domain 17. (2603 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (417 aa)
MBLAC1Metallo-beta-lactamase domain containing 1. (278 aa)
RANBP1RAN binding protein 1. (278 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (832 aa)
NCAPGNon-SMC condensin I complex subunit G. (1013 aa)
DDX3YATP-dependent RNA helicase DDX3Y; Belongs to the DEAD box helicase family. (659 aa)
KAT2BLysine acetyltransferase 2B. (866 aa)
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (240 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSMMUP00000061681Transcription factor. (409 aa)
ENSMMUP00000061990Uncharacterized protein. (876 aa)
MAD2L1BPMAD2L1-binding protein isoform 2. (274 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
EDN1Preproendothelin-1. (211 aa)
PAGR1PAXIP1 associated glutamate rich protein 1. (254 aa)
ANXA1Annexin. (367 aa)
CDC7Cell division cycle 7-related protein kinase. (574 aa)
DDRGK1DDRGK domain-containing protein 1. (314 aa)
CDC14ACell division cycle 14A. (636 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (632 aa)
CD28T-cell-specific surface glycoprotein CD28. (220 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (718 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (265 aa)
LOC717718GFA domain-containing protein. (272 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
PPP1R10Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] (940 aa)
TPRTPR_MLP1_2 domain-containing protein. (2404 aa)
ENSMMUP00000067677Nucleoplasmin domain-containing protein. (183 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4685 aa)
NSMCE2E3 SUMO-protein ligase NSE2. (246 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
TMOD3Uncharacterized protein. (400 aa)
SVILSupervillin. (2331 aa)
MAD2L1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
GIPC3PDZ domain-containing protein. (1440 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2154 aa)
SMPD5Uncharacterized protein. (381 aa)
INO80Putative DNA helicase INO80 complex-like protein 1. (1556 aa)
STILSTIL centriolar assembly protein. (1287 aa)
ANAPC7Anaphase promoting complex subunit 7. (599 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (586 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (740 aa)
INCENPInner centromere protein. (900 aa)
CDC73Parafibromin. (531 aa)
ENSMMUP00000072883Nucleoplasmin domain-containing protein. (250 aa)
RCC2Regulator of chromosome condensation 2. (608 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (462 aa)
AIF1Allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation (By similarity). (147 aa)
RACGAP1Rac GTPase-activating protein 1. (632 aa)
IGF2Insulin like growth factor 2. (244 aa)
RAD21Double-strand-break repair protein rad21 homolog. (631 aa)
FBXO42F-box only protein 42. (716 aa)
E2F8E2F transcription factor 8. (867 aa)
ZNF16Zinc finger protein 16. (682 aa)
BTCBetacellulin. (191 aa)
ENSMMUP00000077290Uncharacterized protein. (218 aa)
PHIPPleckstrin homology domain interacting protein. (1837 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
SOX15SRY-box transcription factor 15. (233 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
LSM11LSM11, U7 small nuclear RNA associated. (358 aa)
ENSMMUP00000078666Uncharacterized protein. (93 aa)
GIPC2PDZ domain-containing protein. (319 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
CDK10Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (385 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (918 aa)
CCND1Uncharacterized protein; Belongs to the cyclin family. (303 aa)
MTBPMDM2 binding protein. (912 aa)
EREGProepiregulin. (169 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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