STRINGSTRING
POU4F1 POU4F1 GTF2H4 GTF2H4 MAFG MAFG MED4 MED4 CEBPE CEBPE NFE2L2 NFE2L2 ENSMMUP00000077416 ENSMMUP00000077416 LOC100426235 LOC100426235 MAF MAF TAF6L TAF6L MED31 MED31 E2F8 E2F8 ATF7 ATF7 HYAL2 HYAL2 RUNX1 RUNX1 TRIP4 TRIP4 ASCL4 ASCL4 THRB THRB TEAD2 TEAD2 TAF7 TAF7 JUN JUN ENY2 ENY2 LMO4 LMO4 NKX2-5 NKX2-5 TAF12 TAF12 RFX5 RFX5 FOS FOS TAF13 TAF13 CBFB CBFB NR5A2 NR5A2 DDIT3 DDIT3 ATF4 ATF4 TAF9B TAF9B ARNTL ARNTL ATF5 ATF5 HOXB9 HOXB9 TBPL1 TBPL1 NCOA1 NCOA1 ATF1 ATF1 TCF15 TCF15 IRF9 IRF9 ERCC3 ERCC3 ATXN7 ATXN7 CEBPG CEBPG SMAD7 SMAD7 GTF2H5 GTF2H5 CREB3 CREB3 ATF6 ATF6 TCF3 TCF3 GTF2H1 GTF2H1 CRX CRX MED26 MED26 CTNNB1 CTNNB1 JDP2 JDP2 MED1 MED1 STAT6 STAT6 MED9 MED9 ENSMMUP00000061681 ENSMMUP00000061681 RUNX3 RUNX3 DBP DBP BATF2 BATF2 GTF2H3 GTF2H3 ENSMMUP00000058345 ENSMMUP00000058345 MED11 MED11 STAT1 STAT1 HIF1A HIF1A E2F5 E2F5 STON1 STON1 JUND JUND ATF6B ATF6B CBX3 CBX3 MED30 MED30 BCL9L BCL9L GTF2H2 GTF2H2 FOSL1 FOSL1 TRRAP TRRAP TAF6 TAF6 TCF4 TCF4 TEAD1 TEAD1 MED25 MED25 SMAD9 SMAD9 NFYA NFYA TCEA1 TCEA1 CEBPB CEBPB MED23 MED23 STAT5A STAT5A CCNH CCNH NFATC2 NFATC2 RB1 RB1 ATF2 ATF2 MYB MYB TBP TBP RXRA RXRA ERCC2 ERCC2 MAFF MAFF MMS19 MMS19 E2F3 E2F3 SMAD2 SMAD2 MED8 MED8 TAF11 TAF11 ENSMMUP00000044764 ENSMMUP00000044764 SMAD6 SMAD6 LEF1 LEF1 STAT3 STAT3 MNAT1 MNAT1 MED14 MED14 TLE3 TLE3 POU2AF1 POU2AF1 TLE1 TLE1 SUPT3H SUPT3H SMAD3 SMAD3 TAF1L TAF1L NONO NONO NFE2 NFE2 F7GDN6_MACMU F7GDN6_MACMU ATF3 ATF3 CREB1 CREB1 MED15 MED15 NR1H3 NR1H3 ASCC2 ASCC2 DRAP1 DRAP1 TAF3 TAF3 F7HPQ7_MACMU F7HPQ7_MACMU F7HPQ9_MACMU F7HPQ9_MACMU MED24 MED24 TCF7 TCF7 MXD3 MXD3 E2F4 E2F4 WWOX WWOX E2F1 E2F1 NR1H2 NR1H2 LOC706619 LOC706619 ARNTL2 ARNTL2 E2F6 E2F6 E2F7 E2F7 TCF7L2 TCF7L2 PASD1 PASD1 HLF HLF NFYB NFYB CREM CREM ASCC3 ASCC3 GTF2A1 GTF2A1 TAF7L TAF7L GEMIN5 GEMIN5 TCF7L1 TCF7L1 TRIM28 TRIM28 ATXN7L3 ATXN7L3 HMGA1 HMGA1 GATA4 GATA4 SFPQ SFPQ CHD4 CHD4 CDK7 CDK7 GTF2A2 GTF2A2 SMAD1 SMAD1 SMAD4 SMAD4 ASCL5 ASCL5 BCL9 BCL9 CREBZF CREBZF CEBPZ CEBPZ TAF4B TAF4B NCOA2 NCOA2 BATF3 BATF3 KAT2A KAT2A TAF2 TAF2 MYC MYC FOSL2 FOSL2 MXI1 MXI1 NR5A1 NR5A1 MED10 MED10 CEBPD CEBPD GTF2F2 GTF2F2 RARA RARA TAF8 TAF8 E2F2 E2F2 MYF5 MYF5 MYF6 MYF6 TAF5 TAF5 PBX1 PBX1 TFDP2 TFDP2 BACH1 BACH1 MED7 MED7 RFXANK RFXANK HAND1 HAND1 MED18 MED18 RFXAP RFXAP NPAS2 NPAS2 BACH2 BACH2 MED16 MED16 TAF5L TAF5L LDB1 LDB1 ING2 ING2 TAF4 TAF4 NEUROD1 NEUROD1 POU2F1 POU2F1 TAF10 TAF10 LOC702124 LOC702124 TFDP1 TFDP1 XBP1 XBP1 LOC695847 LOC695847 VDR VDR PYGO2 PYGO2 TADA3 TADA3 ASCL1 ASCL1 JUNB JUNB TAF1 TAF1 STAT4 STAT4 HLTF HLTF MAX MAX TCF12 TCF12 HNRNPAB HNRNPAB RXRB RXRB BATF BATF NFE2L3 NFE2L3 STAT5B STAT5B YAP1 YAP1 THRA THRA ADNP ADNP FOXH1 FOXH1 MED19 MED19 HIPK2 HIPK2 ASCL3 ASCL3 GTF2E1 GTF2E1 ASCL2 ASCL2 STAT2 STAT2 ARNT ARNT GTF2E2 GTF2E2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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POU4F1POU domain protein. (423 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
MAFGTranscription factor MafG. (162 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (362 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform 1. (606 aa)
ENSMMUP00000077416Uncharacterized protein. (113 aa)
LOC100426235Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (252 aa)
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (403 aa)
TAF6LTAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L. (622 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
E2F8E2F transcription factor 8. (867 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
HYAL2Hyaluronidase. (473 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
TRIP4Thyroid hormone receptor interactor 4. (581 aa)
ASCL4Achaete-scute family bHLH transcription factor 4. (173 aa)
THRBThyroid hormone receptor beta. (524 aa)
TEAD2TEA domain transcription factor 2. (451 aa)
TAF7Transcription initiation factor TFIID subunit 7. (349 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (334 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
LMO4LIM domain only 4. (224 aa)
NKX2-5NK2 homeobox 5. (324 aa)
TAF12TFIID_20kDa domain-containing protein. (214 aa)
RFX5DNA-binding protein RFX5. (620 aa)
FOSV-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa)
TAF13Transcription initiation factor TFIID subunit 13. (124 aa)
CBFBCore-binding factor subunit beta isoform 1. (187 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (541 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa)
ATF4BZIP domain-containing protein. (351 aa)
TAF9BTATA-box binding protein associated factor 9b. (290 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator-like protein 1 isoform a. (626 aa)
ATF5Activating transcription factor 5. (287 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1. (270 aa)
TCF15BHLH domain-containing protein. (197 aa)
IRF9Interferon regulatory factor 9. (455 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
ATXN7SCA7 domain-containing protein. (938 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (150 aa)
SMAD7Mothers against decapentaplegic homolog. (462 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (372 aa)
ATF6Activating transcription factor 6. (821 aa)
TCF3Transcription factor 3. (654 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
CRXCone-rod homeobox. (299 aa)
MED26TFIIS N-terminal domain-containing protein. (615 aa)
CTNNB1Catenin beta-1. (781 aa)
JDP2Jun dimerization protein 2. (525 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
STAT6Signal transducer and activator of transcription. (902 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (156 aa)
ENSMMUP00000061681Transcription factor. (409 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)
DBPD-box binding PAR bZIP transcription factor. (434 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (308 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
ENSMMUP00000058345TAFII28 domain-containing protein. (199 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (206 aa)
STAT1Signal transducer and activator of transcription. (802 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (826 aa)
E2F5E2F transcription factor 5. (346 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (1182 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (432 aa)
ATF6BActivating transcription factor 6 beta. (711 aa)
CBX3Chromobox protein homolog 3. (183 aa)
MED30Mediator of RNA polymerase II transcription subunit 30. (178 aa)
BCL9LBCL9 like. (1500 aa)
GTF2H2General transcription factor IIH subunit. (399 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3873 aa)
TAF6TATA-box binding protein associated factor 6. (678 aa)
TCF4Transcription factor 4. (772 aa)
TEAD1TEA domain transcription factor 1. (641 aa)
MED25Mediator complex subunit 25. (796 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
NFYANuclear transcription factor Y subunit alpha isoform 1. (347 aa)
TCEA1Transcription elongation factor A protein 1 isoform 1. (301 aa)
CEBPBCCAAT/enhancer-binding protein. (344 aa)
MED23Mediator complex subunit 23. (1374 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
CCNHCyclin H; Belongs to the cyclin family. (331 aa)
NFATC2Nuclear factor of activated T cells 2. (925 aa)
RB1Retinoblastoma-associated protein. (928 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
TBPTATA-box binding protein. (326 aa)
RXRARetinoid X receptor alpha. (620 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
MAFFMAF bZIP transcription factor F. (164 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
E2F3E2F transcription factor 3. (465 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (378 aa)
TAF11Transcription initiation factor TFIID subunit 11. (211 aa)
ENSMMUP00000044764TFIIA_gamma_C domain-containing protein. (74 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
STAT3Signal transducer and activator of transcription. (871 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
TLE3TLE family member 3, transcriptional corepressor. (901 aa)
POU2AF1POU class 2 homeobox associating factor 1. (275 aa)
TLE1TLE family member 1, transcriptional corepressor. (804 aa)
SUPT3HUncharacterized protein. (328 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
TAF1LTATA-box binding protein associated factor 1 like. (1776 aa)
NONOUncharacterized protein. (504 aa)
NFE2Nuclear factor, erythroid-derived 2 45 kDa subunit. (373 aa)
F7GDN6_MACMUProtein kinase domain-containing protein. (165 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3 isoform 1. (181 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (788 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
ASCC2Activating signal cointegrator 1 complex subunit 2. (752 aa)
DRAP1Dr1-associated corepressor. (205 aa)
TAF3TATA-box binding protein associated factor 3. (1008 aa)
F7HPQ7_MACMUTAFII28 domain-containing protein. (196 aa)
F7HPQ9_MACMUTAFII28 domain-containing protein. (199 aa)
MED24Mediator of RNA polymerase II transcription subunit 24 isoform 1. (989 aa)
TCF7Transcription factor 7. (571 aa)
MXD3Max dimerization protein 3 isoform a. (206 aa)
E2F4Transcription factor E2F4. (416 aa)
WWOXWW domain containing oxidoreductase. (414 aa)
E2F1E2F transcription factor 1. (437 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
LOC706619Uncharacterized protein. (805 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (636 aa)
E2F6E2F transcription factor 6. (286 aa)
E2F7E2F transcription factor 7. (910 aa)
TCF7L2Transcription factor 7 like 2. (632 aa)
PASD1PAS domain containing repressor 1. (757 aa)
HLFHepatic leukemia factor. (295 aa)
NFYBCBFD_NFYB_HMF domain-containing protein. (208 aa)
CREMcAMP responsive element modulator. (295 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3 isoform a. (2202 aa)
GTF2A1Transcription initiation factor IIA subunit 1 isoform 1. (376 aa)
TAF7LTATA-box binding protein associated factor 7 like. (505 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1512 aa)
TCF7L1Transcription factor 7 like 1. (589 aa)
TRIM28Tripartite motif containing 28. (834 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (347 aa)
HMGA1High mobility group AT-hook 1. (450 aa)
GATA4GATA binding protein 4. (443 aa)
SFPQSplicing factor, proline-and glutamine-rich. (707 aa)
CHD4Chromodomain helicase DNA binding protein 4. (1912 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ASCL5Achaete-scute family bHLH transcription factor 5. (206 aa)
BCL9B-cell CLL/lymphoma 9 protein. (1426 aa)
CREBZFCREB/ATF bZIP transcription factor. (356 aa)
CEBPZCCAAT enhancer binding protein zeta. (1053 aa)
TAF4BTATA-box binding protein associated factor 4b. (862 aa)
NCOA2Nuclear receptor coactivator. (1468 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (147 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
TAF2TATA-box binding protein associated factor 2. (1251 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (471 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
MXI1Max-interacting protein 1 isoform b. (295 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (500 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (135 aa)
CEBPDCCAAT/enhancer-binding protein. (269 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
RARARetinoic acid receptor alpha isoform 1. (462 aa)
TAF8TATA-box binding protein associated factor 8. (367 aa)
E2F2E2F transcription factor 2. (437 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MYF6Myogenic factor 6. (242 aa)
TAF5TATA-box binding protein associated factor 5. (800 aa)
PBX1Pre-B-cell leukemia transcription factor 1 isoform 1. (430 aa)
TFDP2Uncharacterized protein. (490 aa)
BACH1Uncharacterized protein. (763 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa)
RFXANKRegulatory factor X associated ankyrin containing protein. (314 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
RFXAPRegulatory factor X-associated protein. (272 aa)
NPAS2Neuronal PAS domain-containing protein 2. (824 aa)
BACH2BTB domain and CNC homolog 2. (947 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (877 aa)
TAF5LTAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L. (589 aa)
LDB1LIM domain-binding protein 1 isoform 1. (411 aa)
ING2Inhibitor of growth protein. (280 aa)
TAF4TATA-box binding protein associated factor 4. (1083 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
POU2F1POU domain protein. (766 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
LOC702124Uncharacterized protein. (950 aa)
TFDP1Transcription factor. (410 aa)
XBP1X-box binding protein 1. (376 aa)
LOC695847Uncharacterized protein. (183 aa)
VDRVitamin D receptor. (477 aa)
PYGO2Pygopus family PHD finger 2. (405 aa)
TADA3Transcriptional adaptor 3. (462 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (238 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (322 aa)
TAF1Transcription initiation factor TFIID subunit. (1895 aa)
STAT4Signal transducer and activator of transcription. (742 aa)
HLTFHelicase like transcription factor. (1010 aa)
MAXMYC associated factor X. (160 aa)
TCF12Transcription factor 12 isoform a. (706 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B isoform a. (332 aa)
RXRBRetinoid X receptor beta. (537 aa)
BATFBasic leucine zipper ATF-like transcription factor. (137 aa)
NFE2L3Nuclear factor, erythroid 2 like 3. (693 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
YAP1Yes associated protein 1. (508 aa)
THRAThyroid hormone receptor alpha. (486 aa)
ADNPActivity dependent neuroprotector homeobox. (1123 aa)
FOXH1Forkhead box H1. (352 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (244 aa)
HIPK2Homeodomain interacting protein kinase 2. (1212 aa)
ASCL3Achaete-scute family bHLH transcription factor 3. (181 aa)
GTF2E1General transcription factor IIE subunit 1. (450 aa)
ASCL2Achaete-scute family bHLH transcription factor 2. (193 aa)
STAT2Signal transducer and activator of transcription. (851 aa)
ARNTUncharacterized protein. (786 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (320 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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