(20 nodes) Photoreceptor disc membrane network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDE6B	Phosphodiesterase. (839 aa)
	OPN4	Opsin 4. (489 aa)
	SPTBN5	Spectrin beta, non-erythrocytic 5. (3697 aa)
	GUCA1B	Guanylate cyclase activator 1B. (205 aa)
	PDE6A	Phosphodiesterase. (860 aa)
	GUCA1A	Guanylate cyclase activator 1A. (202 aa)
	OPN1LW	Opsin 1, long wave sensitive. (364 aa)
	GRK7	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa)
	GRK1	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (535 aa)
	GUCY2F	Guanylate cyclase. (1108 aa)
	ABCA4	ATP binding cassette subfamily A member 4. (2273 aa)
	GNAT1	G protein subunit alpha i2. (350 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	PDE6G	Phosphodiesterase 6G. (87 aa)
	RHO	Rhodopsin. (348 aa)
	OPN1MW3	G_PROTEIN_RECEP_F1_2 domain-containing protein. (363 aa)
	OPN1SW	Opsin 1, short wave sensitive. (349 aa)
	GUCY2D	Guanylate cyclase. (1145 aa)
	GUCA1C	Guanylate cyclase activator 1C. (210 aa)
	ENSMMUP00000077940	Uncharacterized protein. (113 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA4	GNAT1	ENSMMUP00000018214	ENSMMUP00000026481	ATP binding cassette subfamily A member 4.	G protein subunit alpha i2.	0.414
ABCA4	GUCY2D	ENSMMUP00000018214	ENSMMUP00000073530	ATP binding cassette subfamily A member 4.	Guanylate cyclase.	0.611
ABCA4	PDE6A	ENSMMUP00000018214	ENSMMUP00000006320	ATP binding cassette subfamily A member 4.	Phosphodiesterase.	0.542
ABCA4	PDE6B	ENSMMUP00000018214	ENSMMUP00000004374	ATP binding cassette subfamily A member 4.	Phosphodiesterase.	0.621
ABCA4	RHO	ENSMMUP00000018214	ENSMMUP00000063008	ATP binding cassette subfamily A member 4.	Rhodopsin.	0.731
ENSMMUP00000077940	GRK1	ENSMMUP00000077940	ENSMMUP00000009743	Uncharacterized protein.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.458
ENSMMUP00000077940	GRK7	ENSMMUP00000077940	ENSMMUP00000009694	Uncharacterized protein.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.500
ENSMMUP00000077940	GUCA1A	ENSMMUP00000077940	ENSMMUP00000007415	Uncharacterized protein.	Guanylate cyclase activator 1A.	0.616
ENSMMUP00000077940	GUCY2D	ENSMMUP00000077940	ENSMMUP00000073530	Uncharacterized protein.	Guanylate cyclase.	0.518
ENSMMUP00000077940	PDE6A	ENSMMUP00000077940	ENSMMUP00000006320	Uncharacterized protein.	Phosphodiesterase.	0.498
GNAT1	ABCA4	ENSMMUP00000026481	ENSMMUP00000018214	G protein subunit alpha i2.	ATP binding cassette subfamily A member 4.	0.414
GNAT1	GNGT1	ENSMMUP00000026481	ENSMMUP00000048892	G protein subunit alpha i2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.967
GNAT1	GRK1	ENSMMUP00000026481	ENSMMUP00000009743	G protein subunit alpha i2.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.609
GNAT1	GRK7	ENSMMUP00000026481	ENSMMUP00000009694	G protein subunit alpha i2.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.494
GNAT1	GUCA1A	ENSMMUP00000026481	ENSMMUP00000007415	G protein subunit alpha i2.	Guanylate cyclase activator 1A.	0.501
GNAT1	GUCA1C	ENSMMUP00000026481	ENSMMUP00000076844	G protein subunit alpha i2.	Guanylate cyclase activator 1C.	0.607
GNAT1	GUCY2D	ENSMMUP00000026481	ENSMMUP00000073530	G protein subunit alpha i2.	Guanylate cyclase.	0.647
GNAT1	GUCY2F	ENSMMUP00000026481	ENSMMUP00000017341	G protein subunit alpha i2.	Guanylate cyclase.	0.477
GNAT1	OPN1LW	ENSMMUP00000026481	ENSMMUP00000008106	G protein subunit alpha i2.	Opsin 1, long wave sensitive.	0.690
GNAT1	OPN1MW3	ENSMMUP00000026481	ENSMMUP00000069039	G protein subunit alpha i2.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.533