16 items (Macaca mulatta) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Your Input:
	CBARP	CACN subunit beta associated regulatory protein. (752 aa)
	DRD3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	GNB5	G protein subunit beta 5. (395 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (525 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (511 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
	CACNA1F	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1970 aa)
	DRD4	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (418 aa)
	CRHR1	Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...] (444 aa)
	GPR35	G protein-coupled receptor 35; Belongs to the G-protein coupled receptor 1 family. (309 aa)
	RRAD	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
	REM1	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (306 aa)
	GEM	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
	PPP3R1	Uncharacterized protein. (171 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (547 aa)
	FMR1	Fragile X mental retardation 1 protein isoform ISO1. (632 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNA1F	GNB5	ENSMMUP00000011304	ENSMMUP00000022869	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	G protein subunit beta 5.	0.750
CRHR1	DRD2	ENSMMUP00000055825	ENSMMUP00000018833	Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...]	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.401
CRHR1	DRD4	ENSMMUP00000055825	ENSMMUP00000003580	Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...]	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.416
CRHR1	GNB5	ENSMMUP00000055825	ENSMMUP00000022869	Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...]	G protein subunit beta 5.	0.548
DRD2	CRHR1	ENSMMUP00000018833	ENSMMUP00000055825	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...]	0.401
DRD2	DRD4	ENSMMUP00000018833	ENSMMUP00000003580	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.738
DRD2	GNB5	ENSMMUP00000018833	ENSMMUP00000022869	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 5.	0.953
DRD3	DRD4	ENSMMUP00000030208	ENSMMUP00000003580	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.715
DRD3	GNB5	ENSMMUP00000030208	ENSMMUP00000022869	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 5.	0.945
DRD4	CRHR1	ENSMMUP00000003580	ENSMMUP00000055825	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...]	0.416
DRD4	DRD2	ENSMMUP00000003580	ENSMMUP00000018833	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.738
DRD4	DRD3	ENSMMUP00000003580	ENSMMUP00000030208	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.715
DRD4	GNB5	ENSMMUP00000003580	ENSMMUP00000022869	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 5.	0.455
GNB5	CACNA1F	ENSMMUP00000022869	ENSMMUP00000011304	G protein subunit beta 5.	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	0.750
GNB5	CRHR1	ENSMMUP00000022869	ENSMMUP00000055825	G protein subunit beta 5.	Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...]	0.548
GNB5	DRD2	ENSMMUP00000022869	ENSMMUP00000018833	G protein subunit beta 5.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.953
GNB5	DRD3	ENSMMUP00000022869	ENSMMUP00000030208	G protein subunit beta 5.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.945
GNB5	DRD4	ENSMMUP00000022869	ENSMMUP00000003580	G protein subunit beta 5.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.455
PPP3CA	PPP3CB	ENSMMUP00000060131	ENSMMUP00000020633	Serine/threonine-protein phosphatase.	Serine/threonine-protein phosphatase.	0.870
PPP3CA	PPP3R1	ENSMMUP00000060131	ENSMMUP00000060854	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.994