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| | F6YRS3_MACMU | Ku domain-containing protein. (326 aa) |
| | SLC46A2 | Solute carrier family 46 member 2. (475 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1133 aa) |
| | IL23R | Interleukin 23 receptor. (629 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa) |
| | PCID2 | PCI domain containing 2. (453 aa) |
| | GIMAP5 | AIG1-type G domain-containing protein. (338 aa) |
| | TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa) |
| | ARID1B | AT-rich interaction domain 1B. (2428 aa) |
| | CLPTM1 | CLPTM1 regulator of GABA type A receptor forward trafficking. (674 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa) |
| | FOXP1 | Fork-head domain-containing protein. (695 aa) |
| | UBASH3B | Ubiquitin-associated and SH3 domain-containing protein B. (649 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (153 aa) |
| | STAT5B | Signal transducer and activator of transcription. (787 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (137 aa) |
| | SMARCE1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1. (411 aa) |
| | MAFB | MAF bZIP transcription factor B. (329 aa) |
| | FBN1 | Fibrillin-1. (2871 aa) |
| | DUSP10 | Dual specificity protein phosphatase 10 isoform a; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | HMGB3 | Uncharacterized protein. (201 aa) |
| | PPARGC1B | PPARG coactivator 1 beta. (1023 aa) |
| | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit. (322 aa) |
| | SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (603 aa) |
| | APCS | Pentaxin. (223 aa) |
| | FBXO7 | F-box only protein 7 isoform 1. (522 aa) |
| | NF1 | Neurofibromin 1. (2867 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | ZBTB16 | Uncharacterized protein. (673 aa) |
| | XBP1 | X-box binding protein 1. (376 aa) |
| | IL17A | Interleukin 17A. (155 aa) |
| | ACTL6B | Actin like 6B; Belongs to the actin family. (449 aa) |
| | INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa) |
| | SOX13 | SRY-box 13. (621 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | EVI2B | Ecotropic viral integration site 2B. (451 aa) |
| | FOXP3 | Forkhead box P3. (539 aa) |
| | SHB | SH2 domain containing adaptor protein B. (509 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (335 aa) |
| | PGLYRP1 | Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa) |
| | TRIM2 | Transmembrane 131 like. (1724 aa) |
| | PRELID1 | PRELI domain-containing protein 1, mitochondrial. (219 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform a. (294 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1132 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) |
| | INPP5D | Inositol polyphosphate-5-phosphatase D. (1208 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (626 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (601 aa) |
| | GPR137 | G protein-coupled receptor 137. (472 aa) |
| | DCSTAMP | Dendrocyte expressed seven transmembrane protein. (470 aa) |
| | HAX1 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa) |
| | IFNL1 | Interferon lambda 1. (202 aa) |
| | TNFAIP6 | Tumor necrosis factor-inducible gene 6 protein. (277 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (215 aa) |
| | TOX | Thymocyte selection associated high mobility group box. (526 aa) |
| | JAK3 | Janus kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (602 aa) |
| | SLAMF8 | SLAM family member 8. (285 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1238 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | IL4I1 | Amine oxidase. (589 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (789 aa) |
| | LRRC17 | Leucine rich repeat containing 17. (441 aa) |
| | RARA | Retinoic acid receptor alpha isoform 1. (462 aa) |
| | ARID1A | AT-rich interaction domain 1A. (2287 aa) |
| | HCLS1 | SH3 domain-containing protein. (551 aa) |
| | CR1 | Complement C3b/C4b receptor 1 (Knops blood group). (2041 aa) |
| | MMP14 | Matrix metalloproteinase-14 preproprotein. (582 aa) |
| | MALT1 | MALT1 paracaspase. (824 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (747 aa) |
| | GPR137B | G protein-coupled receptor 137B. (384 aa) |
| | NRARP | Notch-regulated ankyrin repeat-containing protein. (114 aa) |
| | NINJ1 | Ninjurin-1. (152 aa) |
| | SOX4 | Transcription factor SOX. (467 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (471 aa) |
| | HSF1 | Heat shock transcription factor 1. (507 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa) |
| | METTL3 | N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa) |
| | IL15RA | Interleukin 15 receptor subunit alpha. (272 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1586 aa) |
| | PHF10 | PHD finger protein 10. (563 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa) |
| | AP3D1 | AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1215 aa) |
| | CTLA4 | Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM. (223 aa) |
| | ARID2 | AT-rich interaction domain 2. (1836 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (595 aa) |
| | LILRB3 | Ig-like domain-containing protein. (614 aa) |
| | CD101 | CD101 molecule. (1021 aa) |
| | EGK_20852 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa) |
| | PBRM1 | Polybromo 1. (1655 aa) |
| | TESC | Tescalcin isoform 1. (214 aa) |
| | IL2RG | Cytokine receptor common subunit gamma. (369 aa) |
| | ESRRA | Estrogen related receptor alpha. (506 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) |
| | TRAF6 | TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa) |
| | RAG2 | Recombination activating 2. (532 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (826 aa) |
| | AGER | Uncharacterized protein. (403 aa) |
| | KLF10 | Transforming growth factor-beta-inducible early growth response protein 1. (480 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | SLC9B2 | Solute carrier family 9 member B2. (537 aa) |
| | IL15 | Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity); Belongs to the IL-15/IL-21 family. (162 aa) |
| | PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (759 aa) |
| | NFKBID | NFKB inhibitor delta. (464 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa) |
| | PPP2R3C | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (453 aa) |
| | RASSF2 | Ras association domain-containing protein 2. (326 aa) |
| | C1QC | Complement C1q subcomponent subunit C. (245 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa) |
| | PRDM1 | PR/SET domain 1. (820 aa) |
| | ZAP70 | Tyrosine-protein kinase. (619 aa) |
| | NXPE3 | ANK_REP_REGION domain-containing protein. (930 aa) |
| | LOC114673087 | C-C motif chemokine. (67 aa) |
| | TRIB1 | Tribbles pseudokinase 1. (372 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | FOXN1 | Forkhead box N1. (648 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (823 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | PGLYRP2 | Peptidoglycan recognition protein 2. (576 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (314 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (291 aa) |
| | SPINK5 | Serine peptidase inhibitor, Kazal type 5. (1087 aa) |
| | TCF7 | Transcription factor 7. (571 aa) |
| | SH3RF1 | SH3 domain containing ring finger 1. (888 aa) |
| | IKZF3 | Zinc finger protein Aiolos isoform 1. (509 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1126 aa) |
| | POU4F1 | POU domain protein. (423 aa) |
| | LOXL3 | Lysyl oxidase like 3. (753 aa) |
| | LOC704750 | Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | ADA | Adenosine deaminase. (390 aa) |
| | ROR2 | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (942 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (636 aa) |
| | GATA2 | GATA binding protein 2. (480 aa) |
| | IL23A | Interleukin-23 subunit alpha. (189 aa) |
| | IAPP | Islet amyloid polypeptide. (89 aa) |
| | PRDM16 | PR/SET domain 16. (1276 aa) |
| | BTK | Tyrosine-protein kinase. (659 aa) |
| | ZC3H8 | Zinc finger CCCH-type containing 8. (295 aa) |
| | NLRP12 | NLR family pyrin domain containing 12. (1061 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (839 aa) |
| | AXL | AXL receptor tyrosine kinase. (894 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (414 aa) |
| | FBXW7 | F-box/WD repeat-containing protein 7 isoform 1. (707 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (763 aa) |
| | ENSMMUP00000044881 | A_deaminase domain-containing protein. (74 aa) |
| | RHOA | Ras homolog family member A. (209 aa) |
| | IL7R | Interleukin 7 receptor. (459 aa) |
| | IRF1 | Interferon regulatory factor. (325 aa) |
| | SOS2 | Uncharacterized protein. (1332 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2 isoform 1 preproprotein. (2471 aa) |
| | FANCA | FA complementation group A. (1462 aa) |
| | TFE3 | Transcription factor E3. (575 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (344 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (761 aa) |
| | RB1 | Retinoblastoma-associated protein. (928 aa) |
| | SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (470 aa) |
| | TMEM64 | Transmembrane protein 64. (389 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (344 aa) |
| | TNFSF4 | Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (183 aa) |
| | FES | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | ENSMMUP00000051444 | Uncharacterized protein. (214 aa) |
| | CD86 | CD86 molecule. (417 aa) |
| | LYN | Tyrosine-protein kinase. (577 aa) |
| | LIF | LIF interleukin 6 family cytokine. (206 aa) |
| | IL7 | Uncharacterized protein. (184 aa) |
| | ACIN1 | Apoptotic chromatin condensation inducer 1. (1340 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | NLRP3 | NACHT, LRR and PYD domains-containing protein 3; As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, initiates the formation of the inflammasome polymeric complex, made of NLRP3, PYCARD and CASP1 (or possibly CASP4/CASP11). Recruitment of proCASP1 to the inflammasome promotes its activation and CASP1-catalyzed IL1B and IL18 maturation and secretion in the extracellular milieu. Activation of NLRP3 inflammasome is also required for HMGB1 secretion (By similarity). The ac [...] (1035 aa) |
| | FCRL3 | Fc receptor like 3. (752 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1111 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (274 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (771 aa) |
| | LOC100426537 | C-C motif chemokine. (67 aa) |
| | MITF | Microphthalmia-associated transcription factor isoform 1. (520 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | TESPA1 | KRAP_IP3R_bind domain-containing protein. (521 aa) |
| | GLI2 | GLI family zinc finger 2. (1569 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | IL20 | Interleukin 20. (176 aa) |
| | RC3H2 | RING finger and CCCH-type zinc finger domain-containing protein 2 isoform 1. (1191 aa) |
| | LOC708748 | CN hydrolase domain-containing protein. (460 aa) |
| | MDK | Midkine. (143 aa) |
| | FANCD2 | Uncharacterized protein. (1471 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (547 aa) |
| | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1244 aa) |
| | GPR68 | G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (365 aa) |
| | DROSHA | Drosha ribonuclease III. (1379 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa) |
| | IRF4 | Interferon regulatory factor 4 isoform 1. (451 aa) |
| | ENSMMUP00000062204 | Uncharacterized protein. (81 aa) |
| | LOC114669853 | Tyrosine-protein kinase. (1125 aa) |
| | CAMK4 | Calcium/calmodulin-dependent protein kinase type IV; Belongs to the protein kinase superfamily. (473 aa) |
| | CEACAM1 | Uncharacterized protein. (525 aa) |
| | TBX21 | T-box transcription factor 21. (539 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | CALCA | Calcitonin related polypeptide alpha. (140 aa) |
| | TMEM176B | Transmembrane protein 176B. (651 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (462 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | ANXA1 | Annexin. (367 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1437 aa) |
| | ZBTB46 | Zinc finger and BTB domain containing 46. (588 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa) |
| | PGLYRP3 | Peptidoglycan recognition protein 3. (341 aa) |
| | LOC100426567 | Uncharacterized protein. (638 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28. (220 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa) |
| | IL34 | Uncharacterized protein. (364 aa) |
| | CCL3 | C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose- dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) (By similarity). (92 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (415 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1345 aa) |
| | FGL2 | Fibrinogen like 2. (439 aa) |
| | GLI3 | GLI family zinc finger 3. (1580 aa) |
| | BAD | Bcl2 antagonist of cell death. (167 aa) |
| | ZFP36L2 | Zinc finger protein 36, C3H1 type-like 2. (492 aa) |
| | VSIR | V-set immunoregulatory receptor. (311 aa) |
| | IL4R | Interleukin 4 receptor. (825 aa) |
| | CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (293 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa) |
| | CCR2 | C-C chemokine receptor type 2; Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (By similarity). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (By similarity) Also acts as a receptor for the beta-defensin DEFB106A/DEFB106B (By similarity). Regulates the expression of T-cell inflammatory cytokines and T-cell differentiation, promoting the differentiation of T-cells into T-helper 17 cells (Th17) during inflammation (By similari [...] (360 aa) |
| | CBFB | Core-binding factor subunit beta isoform 1. (187 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (533 aa) |
| | FOXJ1 | Forkhead box J1. (421 aa) |
| | PLA2G3 | Phospholipase A2 group III. (509 aa) |
| | FOS | V-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa) |
| | CARTPT | CART prepropeptide. (122 aa) |
| | CCR1 | C-C chemokine receptor type 1; Receptor for a C-C type chemokine. Binds to MIP-1-alpha, RANTES, MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. (355 aa) |
| | CD83 | CD83 antigen isoform a. (205 aa) |
| | ZFPM1 | Zinc finger protein, FOG family member 1. (1024 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa) |
| | LAG3 | Lymphocyte activating 3. (533 aa) |
| | VNN1 | Vanin 1. (513 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1075 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (502 aa) |
| | CRTAM | Cytotoxic and regulatory T cell molecule. (401 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1081 aa) |
| | LOC705334 | Uncharacterized protein. (205 aa) |
| | PF4 | C-X-C motif chemokine. (101 aa) |
| | MAMU-DOA | Ig-like domain-containing protein; Belongs to the MHC class II family. (342 aa) |
| | CD80 | CD80 molecule. (288 aa) |
| | TCTA | Uncharacterized protein. (139 aa) |
| | EGR3 | Early growth response 3. (349 aa) |
| | RNF41 | E3 ubiquitin-protein ligase NRDP1 isoform 1. (317 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | NFAM1 | NFAT activating protein with ITAM motif 1. (271 aa) |
| | LILRB4 | Leukocyte immunoglobulin like receptor B4. (423 aa) |
| | NDFIP1 | Uncharacterized protein. (228 aa) |
| | INHBA | Inhibin subunit beta A. (426 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | ENSMMUP00000077416 | Uncharacterized protein. (113 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1134 aa) |
| | XRCC6 | X-ray repair cross-complementing protein 6. (609 aa) |
| | IL36B | Interleukin-1. (163 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | TMEM178A | Transmembrane protein 178 isoform 1. (297 aa) |
| | HLX | H2.0 like homeobox. (495 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (283 aa) |
| | GAS6 | Growth arrest specific 6. (684 aa) |
| | PRXL2A | Peroxiredoxin (PRX)-like 2 activated in M-CSF stimulated monocytes. (229 aa) |
| | RHOH | Rho-related GTP-binding protein RhoH. (191 aa) |
| | FSTL3 | Uncharacterized protein. (436 aa) |
| | IL27 | Interleukin 27 alpha. (254 aa) |
| | TNFSF18 | Tumor necrosis factor ligand 2A. (199 aa) |
| | TNFRSF11B | TNF receptor superfamily member 11b. (405 aa) |
| | BCL6 | Uncharacterized protein. (735 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
