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OGDH OGDH NDUFS7 NDUFS7 RAC2 RAC2 CAT CAT ENSMMUP00000058612 ENSMMUP00000058612 ENSMMUP00000059313 ENSMMUP00000059313 RRM2 RRM2 LOC701223 LOC701223 SDHD-2 SDHD-2 NDUFS6 NDUFS6 ENSMMUP00000065848 ENSMMUP00000065848 LOC701966 LOC701966 NDUFA2 NDUFA2 LOC702309 LOC702309 NDUFB11 NDUFB11 ENSMMUP00000073706 ENSMMUP00000073706 CYBB CYBB NDUFV2 NDUFV2 ND6 ND6 LOC700087 LOC700087 ENSMMUP00000076360 ENSMMUP00000076360 BCKDHB BCKDHB UQCRQ UQCRQ ENSMMUP00000076876 ENSMMUP00000076876 ENSMMUP00000077370 ENSMMUP00000077370 GMPR GMPR GCSH GCSH NDUFA8 NDUFA8 NDUFS2 NDUFS2 PDK2 PDK2 ENSMMUP00000067920 ENSMMUP00000067920 MRPS36-2 MRPS36-2 ENSMMUP00000069310 ENSMMUP00000069310 ENSMMUP00000069602 ENSMMUP00000069602 NDUFB7 NDUFB7 NDUFA12 NDUFA12 MRPS36 MRPS36 DBT DBT CYBA CYBA NDUFC2 NDUFC2 CYB5B CYB5B IDH3B IDH3B GPD1L GPD1L PDHB PDHB RRM1 RRM1 NDUFS1 NDUFS1 DLD DLD NCF2 NCF2 NDUFA1 NDUFA1 LOC114669847 LOC114669847 GLDC GLDC SDHC SDHC PDK1 PDK1 BCS1L BCS1L LDHC LDHC FOXRED1 FOXRED1 F7EJW4_MACMU F7EJW4_MACMU NDUFB8 NDUFB8 UQCRC2 UQCRC2 BCKDHA BCKDHA ETFB ETFB ND1 ND1 H9H4D5_MACMU H9H4D5_MACMU NDUFS8 NDUFS8 LOC705178 LOC705178 NDUFB1 NDUFB1 RAC1 RAC1 NDUFA4 NDUFA4 NOXA1 NOXA1 NDUFV1 NDUFV1 DLAT DLAT PDHA1 PDHA1 BCKDK BCKDK CBR4 CBR4 WDR93 WDR93 NDUFB2 NDUFB2 SDHD SDHD UQCRC1 UQCRC1 NDUFA6 NDUFA6 GMPR2 GMPR2 IDH3A IDH3A ETFA ETFA RAC3 RAC3 LOC693506 LOC693506 F7CRT4_MACMU F7CRT4_MACMU NDUFB5 NDUFB5 NOX3 NOX3 DUOX2 DUOX2 NOXO1 NOXO1 NCF1 NCF1 CYC1 CYC1 PDHX PDHX NDUFS4 NDUFS4 NDUFS3 NDUFS3 DLST DLST NOX1 NOX1 HSD17B8 HSD17B8 SDHB SDHB NDUFB4 NDUFB4 NDUFV3 NDUFV3 OGDHL OGDHL EMC7 EMC7 CYB5R3 CYB5R3 ENSMMUP00000060037 ENSMMUP00000060037 GPD2 GPD2 P4HB P4HB GPD1 GPD1 LOC704978 LOC704978 ENSMMUP00000061307 ENSMMUP00000061307 NDUFA10 NDUFA10 NCF4 NCF4 NDUFA11 NDUFA11 NDUFA5 NDUFA5 DUOX1 DUOX1 NDUFB3 NDUFB3 NDUFB10 NDUFB10 LOC723069 LOC723069 NDUFB9 NDUFB9 LOC721639 LOC721639 IDH3G IDH3G ENSMMUP00000053635 ENSMMUP00000053635 SDHA SDHA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OGDHOxoglutarate dehydrogenase. (1038 aa)
NDUFS7Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (234 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (533 aa)
ENSMMUP00000058612NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
ENSMMUP00000059313NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (189 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (417 aa)
LOC701223Uncharacterized protein. (140 aa)
SDHD-2Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (85 aa)
NDUFS6zf-CHCC domain-containing protein. (139 aa)
ENSMMUP00000065848NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (157 aa)
LOC701966Uncharacterized protein. (150 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
LOC702309Uncharacterized protein. (150 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (219 aa)
ENSMMUP00000073706NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (118 aa)
CYBBCytochrome b-245 beta chain. (617 aa)
NDUFV2Uncharacterized protein. (253 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (221 aa)
LOC700087Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
ENSMMUP00000076360annotation not available (160 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (392 aa)
UQCRQCytochrome b-c1 complex subunit 8. (82 aa)
ENSMMUP000000768762Fe-2S ferredoxin-type domain-containing protein. (143 aa)
ENSMMUP00000077370Uncharacterized protein. (199 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
GCSHGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (197 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
NDUFS2Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (502 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
ENSMMUP00000067920Protein-serine/threonine kinase. (418 aa)
MRPS36-2Uncharacterized protein. (103 aa)
ENSMMUP00000069310Uncharacterized protein. (106 aa)
ENSMMUP00000069602NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (213 aa)
NDUFB7NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. (137 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
MRPS36Uncharacterized protein. (146 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (527 aa)
CYBAUncharacterized protein. (210 aa)
NDUFC2Uncharacterized protein. (148 aa)
CYB5BCytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (170 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (428 aa)
GPD1LGlycerol-3-phosphate dehydrogenase [NAD(+)]. (351 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (377 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa)
DLDDihydrolipoyl dehydrogenase. (510 aa)
NCF2Neutrophil cytosolic factor 2. (526 aa)
NDUFA1NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1. (70 aa)
LOC114669847Uncharacterized protein. (106 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1020 aa)
SDHCUncharacterized protein. (176 aa)
PDK1Protein-serine/threonine kinase. (436 aa)
BCS1LMitochondrial chaperone BCS1; Belongs to the AAA ATPase family. (419 aa)
LDHCL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (343 aa)
FOXRED1FAD-dependent oxidoreductase domain-containing protein 1. (486 aa)
F7EJW4_MACMUUncharacterized protein. (106 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
UQCRC2Uncharacterized protein; Belongs to the peptidase M16 family. (519 aa)
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (479 aa)
ETFBElectron transfer flavoprotein subunit beta. (317 aa)
ND1Uncharacterized protein. (85 aa)
H9H4D5_MACMUNADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (159 aa)
NDUFS8NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial. (210 aa)
LOC705178Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (264 aa)
NDUFB1Uncharacterized protein. (103 aa)
RAC1Uncharacterized protein. (212 aa)
NDUFA4Cytochrome c oxidase subunit NDUFA4; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport [...] (81 aa)
NOXA1NADPH oxidase activator 1. (479 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (467 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (428 aa)
BCKDKProtein-serine/threonine kinase. (412 aa)
CBR4Carbonyl reductase family member 4. (237 aa)
WDR93WD repeat domain 93. (711 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (105 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (507 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (366 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (401 aa)
ETFAElectron transfer flavoprotein subunit alpha. (346 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
LOC693506Uncharacterized protein. (106 aa)
F7CRT4_MACMUAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (503 aa)
NDUFB5NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 1. (189 aa)
NOX3NADPH oxidase 3. (568 aa)
DUOX2Dual oxidase 2. (1546 aa)
NOXO1NADPH oxidase organizer 1. (378 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
CYC1Cytochrome c1. (325 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (501 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (174 aa)
NDUFS3NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (264 aa)
DLSTLipoyl-binding domain-containing protein. (614 aa)
NOX1NADPH oxidase 1. (564 aa)
HSD17B8Estradiol 17-beta-dehydrogenase 8. (261 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
NDUFB4NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 isoform 2. (119 aa)
NDUFV3NADH:ubiquinone oxidoreductase subunit V3. (473 aa)
OGDHLTransket_pyr domain-containing protein. (1013 aa)
EMC7ER membrane protein complex subunit 7. (242 aa)
CYB5R3NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (345 aa)
ENSMMUP00000060037Uncharacterized protein. (381 aa)
GPD2Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (727 aa)
P4HBProtein disulfide-isomerase. (510 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
LOC7049782-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (267 aa)
ENSMMUP00000061307Uncharacterized protein. (233 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (387 aa)
NCF4Neutrophil cytosolic factor 4. (366 aa)
NDUFA11Uncharacterized protein. (155 aa)
NDUFA5NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (116 aa)
DUOX1Dual oxidase 1. (1554 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (97 aa)
NDUFB10NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10. (178 aa)
LOC723069Succ_DH_flav_C domain-containing protein. (262 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (179 aa)
LOC721639Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (350 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (400 aa)
ENSMMUP00000053635Uncharacterized protein. (264 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (705 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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